P10.24.B SCREENING NON-ONCOLOGICAL DRUGS IN A PATIENT-DERIVED GLIOBLASTOMA MODEL IDENTIFIES PITAVASTATIN WITH POTENTIAL ANTITUMOR ACTIVITY von Zekanovic, S, Achaiber Sing, P, Basuki, A, Koolen, S L W, Ntafoulis, I, den Hollander, C W J, Chien, M P, Li, Y, Mustafa, D A M, Dirven, C M F, Leenstra, S, Lamfers, M L M

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P10.28.B INTERMODEL VARIATION OF BBB PERMEABILITY AFFECTS CNS DRUG DELIVERY IN PDX MODELS OF GBM von Ntafoulis, I, Koolen, S L W, den Hollander, C W J, Goedknegt, E, Haeck, J, Kers, T V, Dijkhuizen, S, van Dis, V, van den Bosch, T P P, Gao, Z, Mezzanotte, L, van Tellingen, O, Dirven, C M F, Leenstra, S, Lamfers, M L M

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Surveillance of premalignant gastric lesions: a multicentre prospective cohort study from low incidence regions von den Hollander, Wouter J, Holster, I Lisanne, den Hoed, Caroline M, Capelle, Lisette G, Tang, Tjon J, Anten, Marie-Paule, Prytz-Berset, Ingrid, Witteman, Ellen M, Ter Borg, Frank, Hartog, Gijsbert den, Bruno, Marco J, Peppelenbosch, Maikel Petrus, Lesterhuis, Wilco, Doukas, Michael, Kuipers, Ernst J, Spaander, Manon C W

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Non-syndromic retinitis pigmentosa von Verbakel, Sanne K., van Huet, Ramon A.C., Boon, Camiel J.F., den Hollander, Anneke I., Collin, Rob W.J., Klaver, Caroline C.W., Hoyng, Carel B., Roepman, Ronald, Klevering, B. Jeroen

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Effects of potent neutralizing antibodies from convalescent plasma in patients hospitalized for severe SARS-CoV-2 infection von Gharbharan, Arvind, Jordans, Carlijn C. E., GeurtsvanKessel, Corine, den Hollander, Jan G., Karim, Faiz, Mollema, Femke P. N., Stalenhoef – Schukken, Janneke E., Dofferhoff, Anthonius, Ludwig, Inge, Koster, Adrianus, Hassing, Robert-Jan, Bos, Jeannet C., van Pottelberge, Geert R., Vlasveld, Imro N., Ammerlaan, Heidi S. M., van Leeuwen – Segarceanu, Elena M., Miedema, Jelle, van der Eerden, Menno, Schrama, Thijs J., Papageorgiou, Grigorios, te Boekhorst, Peter, Swaneveld, Francis H., Mueller, Yvonne M., Schreurs, Marco W. J., van Kampen, Jeroen J. A., Rockx, Barry, Okba, Nisreen M. A., Katsikis, Peter D., Koopmans, Marion P. G., Haagmans, Bart L., Rokx, Casper, Rijnders, Bart J. A.

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PRPH2 mutation update: In silico assessment of 245 reported and 7 novel variants in patients with retinal disease von Peeters, Manon H. C. A, Khan, Mubeen, Rooijakkers, Anoek A. M. B, Mulders, Timo, Haer‐Wigman, Lonneke, Boon, Camiel J. F., Klaver, Caroline C. W., Born, L. Ingeborgh, Hoyng, Carel B., Cremers, Frans P. M., Hollander, Anneke I., Dhaenens, Claire‐Marie, Collin, Rob W. J.

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A new perspective on lipid research in age-related macular degeneration von van Leeuwen, Elisabeth M., Emri, Eszter, Merle, Benedicte M.J., Colijn, Johanna M., Kersten, Eveline, Cougnard-Gregoire, Audrey, Dammeier, Sascha, Meester-Smoor, Magda, Pool, Frances M., de Jong, Eiko K., Delcourt, Cécile, Rodrigez-Bocanegra, Eduardo, Biarnés, Marc, Luthert, Philip J., Ueffing, Marius, Klaver, Caroline C.W., Nogoceke, Everson, den Hollander, Anneke I., Lengyel, Imre

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Ethnicity is a strong predictor for Helicobacter pylori infection in young women in a multi-ethnic European city von den Hollander, Wouter J, Holster, I Lisanne, den Hoed, Caroline M, van Deurzen, Frances, van Vuuren, Anneke J, Jaddoe, Vincent W, Hofman, Albert, Perez Perez, Guillermo I, Blaser, Martin J, Moll, Henriëtte A, Kuipers, Ernst J

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Genetic Risk, Lifestyle, and Age-Related Macular Degeneration in Europe: The EYE-RISK Consortium von Colijn, Johanna M, Meester-Smoor, Magda, Verzijden, Timo, de Breuk, Anita, Silva, Rufino, Merle, Benedicte M J, Cougnard-Grégoire, Audrey, Hoyng, Carel B, Fauser, Sascha, Coolen, Anthonius, Creuzot-Garcher, Catherine, Hense, Hans-Werner, Ueffing, Marius, Delcourt, Cecile, den Hollander, Anneke I, Klaver, Caroline C W

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Helicobacter pylori infection: a predictor of vomiting severity in pregnancy and adverse birth outcome von Grooten, Iris J., MD, Den Hollander, Wouter J., MD, Roseboom, Tessa J., PhD, Kuipers, Ernst J., MD, PhD, Jaddoe, Vincent W., MD, PhD, Gaillard, Romy, PhD, Painter, Rebecca C., MD, PhD

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Homozygosity Mapping Reveals PDE6C Mutations in Patients with Early-Onset Cone Photoreceptor Disorders von Thiadens, Alberta A.H.J., den Hollander, Anneke I., Roosing, Susanne, Nabuurs, Sander B., Zekveld-Vroon, Renate C., Collin, Rob W.J., De Baere, Elfride, Koenekoop, Robert K., van Schooneveld, Mary J., Strom, Tim M., van Lith-Verhoeven, Janneke J.C., Lotery, Andrew J., van Moll-Ramirez, Norka, Leroy, Bart P., van den Born, L. Ingeborgh, Hoyng, Carel B., Cremers, Frans P.M., Klaver, Caroline C.W.

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Expression of Plet1 controls interstitial migration of murine small intestinal dendritic cells von Karrich, Julien J., Romera‐Hernández, Mónica, Papazian, Natalie, Veenbergen, Sharon, Cornelissen, Ferry, Aparicio‐Domingo, Patricia, Stenhouse, Frances H., Peddie, C. Diana, Hoogenboezem, Remco M., den Hollander, Chelsea W. J., Gaskell, Terri, Medley, Tanya, Boon, Louis, Blackburn, C. Clare, Withers, David R., Samsom, Janneke N., Cupedo, Tom

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A Nonsense Mutation in PDE6H Causes Autosomal-Recessive Incomplete Achromatopsia von Kohl, Susanne, Coppieters, Frauke, Meire, Françoise, Schaich, Simone, Roosing, Susanne, Brennenstuhl, Christina, Bolz, Sylvia, van Genderen, Maria M., Riemslag, Frans C.C., Lukowski, Robert, den Hollander, Anneke I., Cremers, Frans P.M., De Baere, Elfride, Hoyng, Carel B., Wissinger, Bernd

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Identification of a 2 Mb Human Ortholog of Drosophila eyes shut/spacemaker that Is Mutated in Patients with Retinitis Pigmentosa von Collin, Rob W.J., Littink, Karin W., Klevering, B. Jeroen, van den Born, L. Ingeborgh, Koenekoop, Robert K., Zonneveld, Marijke N., Blokland, Ellen A.W., Strom, Tim M., Hoyng, Carel B., den Hollander, Anneke I., Cremers, Frans P.M.

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Accuracy of upper endoscopies with random biopsies to identify patients with gastric premalignant lesions who can safely be exempt from surveillance von Mommersteeg, Michiel C., Nieuwenburg, Stella A. V., den Hollander, Wouter J., Holster, Lisanne, den Hoed, Caroline M., Capelle, Lisette G., Tang, Tjon J., Anten, Marie- Paule, Prytz-Berset, Ingrid, Witteman, Ellen M., ter Borg, Frank, Burger, Jordy P. W., Doukas, Michail, Bruno, Marco J., Peppelenbosch, Maikel P., Fuhler, Gwenny M., Kuipers, Ernst J., Spaander, Manon C. W.

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Increased High-Density Lipoprotein Levels Associated with Age-Related Macular Degeneration: Evidence from the EYE-RISK and European Eye Epidemiology Consortia von Colijn, Johanna M, den Hollander, Anneke I, Demirkan, Ayse, Cougnard-Grégoire, Audrey, Verzijden, Timo, Kersten, Eveline, Meester-Smoor, Magda A, Merle, Benedicte M J, Papageorgiou, Grigorios, Ahmad, Shahzad, Mulder, Monique T, Costa, Miguel Angelo, Benlian, Pascale, Bertelsen, Geir, Bron, Alain M, Claes, Birte, Creuzot-Garcher, Catherine, Erke, Maja Gran, Fauser, Sascha, Foster, Paul J, Hammond, Christopher J, Hense, Hans-Werner, Hoyng, Carel B, Khawaja, Anthony P, Korobelnik, Jean-Francois, Piermarocchi, Stefano, Segato, Tatiana, Silva, Rufino, Souied, Eric H, Williams, Katie M, van Duijn, Cornelia M, Delcourt, Cécile, Klaver, Caroline C W

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Skin autofluorescence, a measure of cumulative metabolic stress and advanced glycation end products, predicts mortality in hemodialysis patients von MEERWALDT, Robbert, HARTOG, Jasper W. L, SMIT, Andries J, GRAAFF, Reindert, HUISMAN, Roel J, LINKS, Thera P, DEN HOLLANDER, Nynke C, THORPE, Susan R, BAYNES, John W, NAVIS, Gerjan, GANS, Rijk O. B

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Helicobacter pylori in children with asthmatic conditions at school age, and their mothers von Hollander, W. J., Sonnenschein‐van der Voort, A. M. M., Holster, I. L., Jongste, J. C., Jaddoe, V. W., Hofman, A., Perez‐Perez, G. I., Moll, H. A., Blaser, M. J., Duijts, L., Kuipers, E. J.

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Next-generation genetic testing for retinitis pigmentosa von Neveling, Kornelia, Collin, Rob W.J., Gilissen, Christian, van Huet, Ramon A.C., Visser, Linda, Kwint, Michael P., Gijsen, Sabine J., Zonneveld, Marijke N., Wieskamp, Nienke, de Ligt, Joep, Siemiatkowska, Anna M., Hoefsloot, Lies H., Buckley, Michael F., Kellner, Ulrich, Branham, Kari E., den Hollander, Anneke I., Hoischen, Alexander, Hoyng, Carel, Klevering, B. Jeroen, van den Born, L. Ingeborgh, Veltman, Joris A., Cremers, Frans P.M., Scheffer, Hans

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Mutations in C8orf37, Encoding a Ciliary Protein, are Associated with Autosomal-Recessive Retinal Dystrophies with Early Macular Involvement von Estrada-Cuzcano, Alejandro, Neveling, Kornelia, Kohl, Susanne, Banin, Eyal, Rotenstreich, Ygal, Sharon, Dror, Falik-Zaccai, Tzipora C., Hipp, Stephanie, Roepman, Ronald, Wissinger, Bernd, Letteboer, Stef J.F., Mans, Dorus A., Blokland, Ellen A.W., Kwint, Michael P., Gijsen, Sabine J., van Huet, Ramon A.C., Collin, Rob W.J., Scheffer, H., Veltman, Joris A., Zrenner, Eberhart, den Hollander, Anneke I., Klevering, B. Jeroen, Cremers, Frans P.M.

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