BRCA Mutation Frequency and Patterns of Treatment Response in BRCA Mutation–Positive Women With Ovarian Cancer: A Report From the Australian Ovarian Cancer Study Group von ALSOP, Kathryn, FEREDAY, Sian, FRIEDLANDER, Michael, FOX, Stephen, BOWTELL, David, MITCHELL, Gillian, MELDRUM, Cliff, DEFAZIO, Anna, EMMANUEL, Catherine, GEORGE, Joshy, DOBROVIC, Alexander, BIRRER, Michael J, WEBB, Penelope M, STEWART, Colin

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Multiple ABCB1 transcriptional fusions in drug resistant high-grade serous ovarian and breast cancer von Christie, Elizabeth L., Pattnaik, Swetansu, Beach, Jessica, Copeland, Anthony, Rashoo, Nineveh, Fereday, Sian, Hendley, Joy, Alsop, Kathryn, Brady, Samuel L., Lamb, Greg, Pandey, Ahwan, deFazio, Anna, Thorne, Heather, Bild, Andrea, Bowtell, David D. L.

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Driver mutations in TP53 are ubiquitous in high grade serous carcinoma of the ovary von Ahmed, Ahmed Ashour, Etemadmoghadam, Dariush, Temple, Jillian, Lynch, Andy G, Riad, Mohamed, Sharma, Raghwa, Stewart, Colin, Fereday, Sian, Caldas, Carlos, deFazio, Anna, Bowtell, David, Brenton, James D

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Novel Molecular Subtypes of Serous and Endometrioid Ovarian Cancer Linked to Clinical Outcome von TOTHILL, Richard W, TINKER, Anna V, TRAFICANTE, Nadia, FEREDAY, Sian, HUNG, Jillian A, CHIEW, Yoke-Eng, HAVIV, Izhak, GERTIG, Dorota, DEFAZIO, Anna, BOWTELL, David D. L, GEORGE, Joshy, BROWN, Robert, FOX, Stephen B, LADE, Stephen, JOHNSON, Daryl S, TRIVETT, Melanie K, ETEMADMOGHADAM, Dariush, LOCANDRO, Bianca

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Strategies to enable large-scale proteomics for reproducible research von Poulos, Rebecca C., Hains, Peter G., Shah, Rohan, Lucas, Natasha, Xavier, Dylan, Manda, Srikanth S., Anees, Asim, Koh, Jennifer M. S., Mahboob, Sadia, Wittman, Max, Williams, Steven G., Sykes, Erin K., Hecker, Michael, Dausmann, Michael, Wouters, Merridee A., Ashman, Keith, Yang, Jean, Wild, Peter J., deFazio, Anna, Balleine, Rosemary L., Tully, Brett, Aebersold, Ruedi, Speed, Terence P., Liu, Yansheng, Reddel, Roger R., Robinson, Phillip J., Zhong, Qing

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Acquired RAD51C Promoter Methylation Loss Causes PARP Inhibitor Resistance in High-Grade Serous Ovarian Carcinoma von Nesic, Ksenija, Kondrashova, Olga, Hurley, Rachel M., McGehee, Cordelia D., Vandenberg, Cassandra J., Ho, Gwo-Yaw, Lieschke, Elizabeth, Dall, Genevieve, Bound, Nirashaa, Shield-Artin, Kristy, Radke, Marc, Musafer, Ashan, Chai, Zi Qing, Ghamsari, Mohammad Reza Eftekhariyan, Harrell, Maria, Kee, Damien, Olesen, Inger, McNally, Orla, Traficante, Nadia, DeFazio, Anna, Bowtell, David D. L., Swisher, Elizabeth M., Weroha, S. John, Nones, Katia, Waddell, Nicola, Kaufmann, Scott H., Dobrovic, Alexander, Wakefield, Matthew J., Scott, Clare L.

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A Myc Activity Signature Predicts Poor Clinical Outcomes in Myc-Associated Cancers von Jung, MoonSun, Russell, Amanda J, Liu, Bing, George, Joshy, Liu, Pei Yan, Liu, Tao, DeFazio, Anna, Bowtell, David D L, Oberthuer, André, London, Wendy B, Fletcher, Jamie I, Haber, Michelle, Norris, Murray D, Henderson, Michelle J

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Response rates to second-line platinum-based therapy in ovarian cancer patients challenge the clinical definition of platinum resistance von Lindemann, Kristina, Gao, Bo, Mapagu, Cristina, Fereday, Sian, Emmanuel, Catherine, Alsop, Kathryn, Traficante, Nadia, Harnett, Paul R., Bowtell, David D.L., deFazio, Anna

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Health services costs for ovarian cancer in Australia: Estimates from the 45 and Up Study von Goldsbury, David E, Vassallo, Amy, Weber, Marianne F, Steinberg, Julia, Webb, Penelope M, DeFazio, Anna, Canfell, Karen

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Increased prevalence of obstructive sleep apnea in women diagnosed with endometrial or breast cancer von Madut, Ayey, Fuchsova, Veronika, Man, Hong, Askar, Shabeel, Trivedi, Ritu, Elder, Elisabeth, Clarke, Christine L., Wain, Gerard, Brand, Alison, DeFazio, Anna, Amis, Terence, Kairaitis, Kristina

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Integrated Genome-Wide DNA Copy Number and Expression Analysis Identifies Distinct Mechanisms of Primary Chemoresistance in Ovarian Carcinomas von ETEMADMOGHADAM, Dariush, DEFAZIO, Anna, LADE, Stephen, AKSLEN, Lars A, TINKER, Anna V, LOCANDRO, Bianca, ALSOP, Kathryn, CHIEW, Yoke-Eng, TRAFICANTE, Nadia, FEREDAY, Sian, JOHNSON, Daryl, FOX, Stephen, BEROUKHIM, Rameen, SELLERS, William, URASHIMA, Mitsuyoshi, SALVESEN, Helga B, MEYERSON, Matthew, BOWTELL, David, MERMEL, Craig, GEORGE, Joshy, GETZ, Gad, TOTHILL, Richard, OKAMOTO, Aikou, RAEDER, Maria B, HARNETT, Paul

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Profiles of Genomic Instability in High-Grade Serous Ovarian Cancer Predict Treatment Outcome von WANG, Zhigang C, JUUL BIRKBAK, Nicolai, LIU, Joyce, ETEMADMOGHADAM, Dariush, MIRON, Alexander, SALVESEN, Helga B, MITCHELL, Gillian, DEFAZIO, Anna, QUACKENBUSH, John, BERKOWITZ, Ross S, DIRK IGLEHART, J, BOWTELL, David D. L, CULHANE, Aedin C, MATULONIS, Ursula A, DRAPKIN, Ronny, FATIMA, Aquila, RUIYANG TIAN, SCHWEDE, Matthew, ALSOP, Kathryn, DANIELS, Kathryn E, HUIYING PIAO

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The RING finger domain E3 ubiquitin ligases BRCA1 and the RNF20/RNF40 complex in global loss of the chromatin mark histone H2B monoubiquitination (H2Bub1) in cell line models and p... von Dickson, Kristie-Ann, Cole, Alexander J, Gill, Anthony J, Clarkson, Adele, Gard, Gregory B, Chou, Angela, Kennedy, Catherine J, Henderson, Beric R, Fereday, Sian, Traficante, Nadia, Alsop, Kathryn, Bowtell, David D, deFazio, Anna, Clifton-Bligh, Roderick, Marsh, Deborah J

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Self-reported awareness of genetic testing, the impact of family history, and access to clinical trials for people diagnosed with ovarian cancer in Australia von Roczo, Deborah, Alford, Vanessa, Trainer, Alison, DeFazio, Anna, Pearn, Amy, Delaney, Caitlin, Cotter, Megan, Hegarty, Sue

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Irregular Sleep/Wake Patterns Are Associated With Reduced Quality of Life in Post-treatment Cancer Patients: A Study Across Three Cancer Cohorts von Trivedi, Ritu, Man, Hong, Madut, Ayey, Mather, Marius, Elder, Elisabeth, Dhillon, Haryana M., Brand, Alison, Howle, Julie, Mann, Graham, DeFazio, Anna, Amis, Terence, Cain, Sean W., Phillips, Andrew J. K., Kairaitis, Kristina

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Screening for obstructive sleep apnoea in post‐treatment cancer patients von Subramanian, Harini, Fuchsova, Veronika, Elder, Elisabeth, Brand, Alison, Howle, Julie, DeFazio, Anna, Mann, Graham J., Amis, Terence, Kairaitis, Kristina

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Older age should not be a barrier to testing for somatic variants in homologous recombination DNA repair-related genes in patients with high-grade serous ovarian carcinoma von Pitiyarachchi, Omali, Lee, Yeh Chen, Sim, Hao-Wen, Srirangan, Sivatharsny, Mapagu, Cristina, Kirk, Judy, Harnett, Paul R., Balleine, Rosemary L., Bowtell, David D.L., Samimi, Goli, Brand, Alison H., Marsh, Deborah J., Beale, Philip, Anderson, Lyndal, Bouantoun, Natalie, Provan, Pamela, Ramus, Susan J., DeFazio, Anna, Friedlander, Michael

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ABCB1 (MDR 1) Polymorphisms and Progression-Free Survival among Women with Ovarian Cancer following Paclitaxel/Carboplatin Chemotherapy von Johnatty, Sharon E, Beesley, Jonathan, Paul, Jim, Fereday, Sian, Spurdle, Amanda B, Webb, Penelope M, Byth, Karen, Marsh, Sharon, McLeod, Howard, Harnett, Paul R, Brown, Robert, DeFazio, Anna, Chenevix-Trench, Georgia

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Mutation of ERBB2 Provides a Novel Alternative Mechanism for the Ubiquitous Activation of RAS-MAPK in Ovarian Serous Low Malignant Potential Tumors von Anglesio, Michael S, Arnold, Jeremy M, George, Joshy, Tinker, Anna V, Tothill, Richard, Waddell, Nic, Simms, Lisa, Locandro, Bianca, Fereday, Sian, Traficante, Nadia, Russell, Peter, Sharma, Raghwa, Birrer, Michael J, deFazio, Anna, Chenevix-Trench, Georgia, Bowtell, David D L

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Improved ovarian cancer EMT-CTC isolation by immunomagnetic targeting of epithelial EpCAM and mesenchymal N-cadherin von Po, Joseph W, Roohullah, Aflah, Lynch, David, DeFazio, Anna, Harrison, Michelle, Harnett, Paul R, Kennedy, Catherine, de Souza, Paul, Becker, Therese M

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