Tumor Necrosis Factor α As a New Target for Renal Cell Carcinoma: Two Sequential Phase II Trials of Infliximab at Standard and High Dose von Harrison, Michelle L, Obermueller, Eva, Maisey, Nick R, Hoare, Susan, Edmonds, Kim, Li, Ningfeng F, Chao, David, Hall, Kate, Lee, Chooi, Timotheadou, Eleni, Charles, Kellie, Ahern, Roger, King, D Mike, Eisen, Tim, Corringham, Robert, DeWitte, Mark, Balkwill, Frances, Gore, Martin

Volltext

Therapeutic potential of cytokine and chemokine antagonists in cancer therapy von Yan, Li, Anderson, G. Mark, DeWitte, Mark, Nakada, Marian T.

Volltext

Cantuzumab Mertansine, a Maytansinoid Immunoconjugate Directed to the CanAg Antigen: A Phase I, Pharmacokinetic, and Biologic Correlative Study von TOLCHER, Anthony W, OCHOA, Leonel, JONAK, Zdenka L, JOHNSON, Randall, DEWITTE, Mark, MARTINO, Helen, AUDETTE, Charlene, MAES, Kate, CHARI, Ravi V. J, LAMBERT, John M, ROWINSKY, Eric K, HAMMOND, Lisa A, PATNAIK, Amita, EDWARDS, Tam, TAKIMOTO, Chris, SMITH, Lon, DE BONO, Johann, SCHWARTZ, Garry, MAYS, Theresa

Volltext

A Phase I Study of Cantuzumab Mertansine Administered as a Single Intravenous Infusion Once Weekly in Patients with Advanced Solid Tumors von HELFT, Paul R, SCHILSKY, Richard L, RUSSO, Mark, LAMBERT, John M, HOWARD, Maria, RATAIN, Mark J, HOKE, Frank J, WILLIAMS, Daphne, KINDLER, Hedy L, SPRAGUE, Evie, DEWITTE, Mark, MARTINO, Helen K, ERICKSON, John, PANDITE, Lini

Volltext

Oral Topotecan as Single-Agent Second-Line Chemotherapy in Patients With Advanced Ovarian Cancer von CLARKE-PEARSON, D. L, VAN LE, L, DEWITTE, Mark H, FIELDS, S. Z, IVESON, T, WHITNEY, C. W, HANJANI, P, KRISTENSEN, G, MALFETANO, J. H, BECKMAN, R. A, ROSS, G. A, LANE, S. R

Volltext

Formation, Clearance, Deposition, Pathogenicity, and Identification of Biopharmaceutical-related Immune Complexes: Review and Case Studies von Rojko, Jennifer L., Evans, Mark G., Price, Shari A., Han, Bora, Waine, Gary, DeWitte, Mark, Haynes, Jill, Freimark, Bruce, Martin, Pauline, Raymond, James T., Evering, Winston, Rebelatto, Marlon C., Schenck, Emanuel, Horvath, Christopher

Volltext

Tumor necrosis factor-α in the pathogenesis and treatment of cancer von Anderson, G Mark, Nakada, Marian T, DeWitte, Mark

Volltext

Minimal Residual Disease (MRD) As Exploratory Endpoint in a Phase 1 Study of the Anti-CD123 Mab CSL362 Given As Post-Remission Therapy in Adult Acute Myeloid Leukemia (AML) von Smith, B. Douglas, Roberts, Andrew W., Roboz, Gail J., DeWitte, Mark, Ferguson, Anna, Garrett, Linda, Curcio, Tania, Orlowski, Kaysey F., Dasen, Sue, Bensen-Kennedy, Debra M., Walter, Roland B.

Volltext

Pharmacodynamic Activity and Preclinical Safety of CSL362, a Novel Humanised, Affinity Matured Monoclonal Antibody Against Human Interleukin 3 Receptor von Herzog, Eva, Busfield, Samantha, Biondo, Mark, Vairo, Gino, DeWitte, Mark, Pragst, Ingo, Dickneite, Gerhard, Nash, Andrew, Zollner, Sabine

Volltext

Fatigue in patients with advanced cancer: a pilot study of an intervention with infliximab von Tookman, A. J., Jones, C. L., DeWitte, Mark, Lodge, P. J.

Volltext

First-in Man, Phase 1 Study of CSL362 (Anti-IL3Rα / Anti-CD123 Monoclonal Antibody) in Patients with CD123+ Acute Myeloid Leukemia (AML) in CR at High Risk for Early Relapse von Smith, B. Douglas, Roboz, Gail J., Walter, Roland B., Altman, Jessica K., Ferguson, Anna, Curcio, Tania J., Orlowski, Kaysey F., Garrett, Linda, Busfield, Samantha J, Barnden, Megan, Sedgmen, Brad, Ghosh, Souravi, Hosback, Sarah, Davis, Roslyn, Dyson, Allison, Dasen, Sue, DeWitte, Mark, Bensen-Kennedy, Debra M., Roberts, Andrew W.

Volltext

Analysis of creep in a welded ‘P91’ pressure vessel von Eggeler, Gunther, Ramteke, Ashok, Coleman, Mike, Chew, Brian, Peter, Gerhard, Burblies, Andreas, Hald, John, Jefferey, Clive, Rantala, Jahani, deWitte, Mark, Mohrmann, Ralf

Volltext

CSL362: A Monoclonal Antibody to Human Interleukin-3 Receptor (CD123), Optimized for NK Cell-Mediated Cytotoxicity of AML Stem Cells von Busfield, Samantha J., Biondo, Mark, Wong, Mae, Ramshaw, Hayley S., Lee, Erwin M, Martin, Kirstee, Ghosh, Souravi, Braley, Hal, Tomasetig, Vesna, Panousis, Con, Vairo, Gino, Roberts, Andrew W., He, Simon Z., Sprigg, Naomi, Thomas, Daniel, DeWitte, Mark, Lock, Richard B., Lopez, Angel F., Nash, Andrew

Volltext

Preliminary Results of CNTO 328, an Anti-Interleukin (IL)-6 Monoclonal Antibody (mAb), in Combination with Bortezomib in the Treatment of Relapsed or Refractory Multiple Myeloma von Manges, Robert F., Sutherland, Heather J., Jagannath, Sundar, Orlowski, Robert Z., La Police, David, DeWitte, Mark, Lang, Zhihui, Corringham, Robert E., Rossi, Jean Francois

Volltext

A Phase 1 and Correlative Biological Study of CSL360 (anti-CD123 mAb) in AML von Roberts, Andrew W., He, Simon, Bradstock, Kenneth F, Hertzberg, Mark S, Durrant, Simon T S, Ritchie, David, Lewis, Ian D., Marlton, Paula, McLachlan, Andrew J, Yeadon, Trina M, Busfield, Samantha J, Barnden, Megan J, Davis, Roslyn, Hosback, Sarah, Mirosa, Danijela, Biondo, Mark, Bamford, Simone, DeWitte, Mark, Basser, Russell

Volltext

Tumor necrosis factor a as a new target for renal cell carcinoma : Two sequential phase II trials of infliximab at standard and high dose von HARRISON, Michelle L, OBERMUELLER, Eva, CHARLES, Kellie, AHERN, Roger, KING, D. Mike, EISEN, Tim, CORRINGHAM, Robert, DEWITTE, Mark, BALKWILL, Frances, GORE, Martin, MAISEY, Nick R, HOARE, Susan, EDMONDS, Kim, LI, Ningfeng F, CHAO, David, HALL, Kate, LEE, Chooi, TIMOTHEADOU, Eleni

Volltext

Aneurysm Study of Pipeline in an Observational Registry (ASPIRe) von Kallmes, David F., Brinjikji, Waleed, Boccardi, Edoardo, Ciceri, Elisa, Diaz, Orlando, Tawk, Rabih, Woo, Henry, Jabbour, Pascal, Albuquerque, Felipe, Chapot, Rene, Bonafe, Alain, Dashti, Shervin R., Delgado Almandoz, Josser E., Given II, Curtis, Kelly, Michael E., Cross III, DeWitte T., Duckwiler, Gary, Razack, Nasser, Powers, Ciaran J., Fischer, Sebastian, Lopes, Demetrius, Harrigan, Mark R., Huddle, Daniel, Turner IV, Raymond, Zaidat, Osama O., Defreyne, Luc, Mendes Pereira, Vitor, Cekirge, Saruhan, Fiorella, David, Hanel, Ricardo A., Lylyk, Pedro, McDougall, Cameron, Siddiqui, Adnan, Szikora, Istvan, Levy, Elad

Volltext

Estimating the reproducibility of psychological science von Aarts, Alexander A., Nilsonne, Gustav, Zuni, Kellylynn

Volltext

Patisiran Treatment in Patients with Transthyretin Cardiac Amyloidosis von Maurer, Mathew S., Kale, Parag, Fontana, Marianna, Berk, John L., Grogan, Martha, Gustafsson, Finn, Hung, Rebecca R., Gottlieb, Robert L., Damy, Thibaud, González-Duarte, Alejandra, Sarswat, Nitasha, Sekijima, Yoshiki, Tahara, Nobuhiro, Taylor, Mark S., Kubanek, Milos, Donal, Erwan, Palecek, Tomas, Tsujita, Kenichi, Tang, W.H. Wilson, Yu, Wen-Chung, Obici, Laura, Simões, Marcus, Fernandes, Fábio, Poulsen, Steen Hvitfeldt, Diemberger, Igor, Perfetto, Federico, Solomon, Scott D., Di Carli, Marcelo, Badri, Prajakta, White, Matthew T., Chen, Jihong, Yureneva, Elena, Sweetser, Marianne T., Jay, Patrick Y., Garg, Pushkal P., Vest, John, Gillmore, Julian D.

Volltext

Observations of the impact of a major Saharan dust storm on the atmospheric radiation balance von Slingo, A., Ackerman, T. P., Allan, R. P., Kassianov, E. I., McFarlane, S. A., Robinson, G. J., Barnard, J. C., Miller, M. A., Harries, J. E., Russell, J. E., Dewitte, S.

Volltext