Inhibition of farnesyltransferase induces regression of mammary and salivary carcinomas in ras transgenic mice von Kohl, Nancy E, Omer, Charles A, Conner, Michael W, Anthony, Neville J, Davide, Joseph P, Desolms, S. Jane, Giuliani, Elizabeth A, Gomez, Robert P, Graham, Samuel L, Hamilton, Kelly, Handt, Laurence K, Hartman, George D, Koblan, Kenneth S, Kral, Astrid M, Miller, Patricia J, Mosser, Scott D, O'Neill, Timothy J, Rands, Elaine, Schaber, Michael D, Gibbs, Jackson B, Oliff, Allen

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Dual Protein Farnesyltransferase−Geranylgeranyltransferase-I Inhibitors as Potential Cancer Chemotherapeutic Agents von deSolms, S. Jane, Ciccarone, Terrence M, MacTough, Suzanne C, Shaw, Anthony W, Buser, Carolyn A, Ellis-Hutchings, Michelle, Fernandes, Christine, Hamilton, Kelly A, Huber, Hans E, Kohl, Nancy E, Lobell, Robert B, Robinson, Ronald G, Tsou, Nancy N, Walsh, Eileen S, Graham, Samuel L, Beese, Lorena S, Taylor, Jeffrey S

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P450 interaction with farnesyl-protein transferase inhibitors metabolic stability, inhibitory potency, and P450 binding spectra in human liver microsomes von CHIBA, Masato, CUYUE TANG, NEWAY, William E, WILLIAMS, Theresa M, DESOLMS, S. Jane, DINSMORE, Christopher J, WAI, John S, LIN, Jiunn H

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Evaluation of farnesyl:Protein transferase and geranylgeranyl:Protein transferase inhibitor combinations in preclinical models von LOBELL, Robert B, OMER, Charles A, KRAL, Astrid M, DONGMING LIU, LUMMA, William C, MACHOTKA, Samuel V, RANDS, Elaine, WILLIAMS, Theresa M, GRAHAM, Samuel L, HARTMAN, George D, OLIFF, Allen I, HEIMBROOK, David C, ABRAMS, Marc T, KOHL, Nancy E, BHIMNATHWALA, Hema G, BRUCKER, Mary Jo, BUSER, Carolyn A, DAVIDE, Joseph P, DESOLMS, S. Jane, DINSMORE, Christopher J, ELLIS-HUTCHINGS, Michelle S

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Asymmetric synthesis of α,α-diaryl and α-aryl-α-heteroaryl alkylamines by organometallic additions to N-tert- butanesulfinyl ketimines von Shaw, Anthony W, deSolms, S.Jane

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Selective Inhibition of ras-Dependent Transformation by a Farnesyltransferase Inhibitor von Kohl, Nancy E., Mosser, Scott D., deSolms, S. Jane, Giuliani, Elizabeth A., Pompliano, David L., Graham, Samuel L., Smith, Robert L., Scolnick, Edward M., Oliff, Allen, Gibbs, Jackson B.

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The total synthesis of D- and L-myo-inositol 1,4,5-trisphosphate von Vacca, Joseph P, DeSolms, S. Jane, Huff, Joel R

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Protein Farnesyltransferase Inhibitors Block the Growth of ras-Dependent Tumors in Nude Mice von Kohl, Nancy E., Wilson, Francine R., Mosser, Scott D., Giuliani, Elizabeth, deSolms, S. Jane, Conner, Michael W., Anthony, Neville J., Holtz, Wilbur J., Gomez, Robert P., Lee, Ta-Jyh, Smith, Robert L., Graham, Samuel L., Hartman, George D., Gibbs, Jackson B., Oliff, Allen

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Farnesyltransferase inhibition causes morphological reversion of ras-transformed cells by a complex mechanism that involves regulation of the actin cytoskeleton von Prendergast, G C, Davide, J P, deSolms, S J, Giuliani, E A, Graham, S L, Gibbs, J B, Oliff, A, Kohl, N E

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A priori prediction of activity for HIV-1 protease inhibitors employing energy minimization in the active site von Holloway, M. Katharine, Wai, Jenny M, Halgren, Thomas A, Fitzgerald, Paula M. D, Vacca, Joseph P, Dorsey, Bruce D, Levin, Rhonda B, Thompson, Wayne J, Chen, L. Jenny

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The total synthesis of myo-inositol phosphates via myo-inositol orthoformate von BILLINGTON, D. C, BAKER, R, KULAGOWSKI, J. J, MAWER, I. M, VACCA, J. P, DESOLMS, S. J, HUFF, J. R

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Synthesis of the taxane diterpenes: Construction of a bc ring intermediate for taxane synthesis von Swindell, Charles S., Jane deSolms, S.

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Mutational analysis of conserved residues of the beta-subunit of human farnesyl:protein transferase von Kral, A M, Diehl, R E, deSolms, S J, Williams, T M, Kohl, N E, Omer, C A

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(Acylaryloxy)acetic acid diuretics. 2. (2-Alkyl-2-aryl-1-oxo-5-indanyloxy)acetic acids von DeSolms, S. Jane, Woltersdorf, Otto W, Cragoe, Edward J, Watson, L. Sherman, Fanelli, George M

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Potent, non-thiol inhibitors of farnesyltransferase von Breslin, Michael J., deSolms, S.Jane, Giuliani, Elizabeth A., Stokker, Gerald E., Graham, Samuel L., Pompliano, David L., Mosser, Scott D., Hamilton, Kelly A., Hutchinson, John H.

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Diaryl ether inhibitors of farnesyl-protein transferase von MacTough, Suzanne C., deSolms, S.Jane, Shaw, Anthony W., Abrams, Marc T., Ciccarone, Terrence M., Davide, Joseph P., Hamilton, Kelly A., Hutchinson, John H., Koblan, Kenneth S., Kohl, Nancy E., Lobell, Robert B., Robinson, Ronald G., Graham, Samuel L.

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(Acylaryloxy)acetic acid diuretics. 4. Indeno[5,4-b]furan-2-carboxylic acids von Woltersdorf, Otto W, deSolms, S. Jane, Cragoe, Edward J

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N-Arylalkyl Pseudopeptide Inhibitors of Farnesyltransferase von deSolms, S. Jane, Giuliani, Elizabeth A, Graham, Samuel L, Koblan, Kenneth S, Kohl, Nancy E, Mosser, Scott D, Oliff, Allen I, Pompliano, David L, Rands, Elaine, Scholz, Thomas H, Wiscount, Catherine M, Gibbs, Jackson B, Smith, Robert L

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NMR studies of novel inhibitors bound to farnesyl‐protein transferase von Koblan, Kenneth S., Mosser, Scott D., Omer, Charles A., Christopher Culberson, J., Jane Desolms, S., Giuliani, Elizabeth A., Pitzenberger, Steven M., Bogusky, Michael J.

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P450 interaction with farnesyl-protein transferase inhibitors metabolic stability, inhibitory potency, and P450 binding spectra in human liver microsomes 1 1Abbreviations: FTI, far... von Chiba, Masato, Tang, Cuyue, Neway, William E, Williams, Theresa M, Jane Desolms, S, Dinsmore, Christopher J, Wai, John S, Lin, Jiunn H

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