Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors von Gomez Perdiguero, Elisa, Klapproth, Kay, Schulz, Christian, Busch, Katrin, Azzoni, Emanuele, Crozet, Lucile, Garner, Hannah, Trouillet, Celine, de Bruijn, Marella F., Geissmann, Frederic, Rodewald, Hans-Reimer

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Combinatorial Transcriptional Control In Blood Stem/Progenitor Cells: Genome-wide Analysis of Ten Major Transcriptional Regulators von Wilson, Nicola K., Foster, Samuel D., Wang, Xiaonan, Knezevic, Kathy, Schütte, Judith, Kaimakis, Polynikis, Chilarska, Paulina M., Kinston, Sarah, Ouwehand, Willem H., Dzierzak, Elaine, Pimanda, John E., de Bruijn, Marella F.T.R., Göttgens, Berthold

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Microhomologies are prevalent at Cas9-induced larger deletions von Owens, Dominic D G, Caulder, Adam, Frontera, Vincent, Harman, Joe R, Allan, Alasdair J, Bucakci, Akin, Greder, Lucas, Codner, Gemma F, Hublitz, Philip, McHugh, Peter J, Teboul, Lydia, de Bruijn, Marella F T R

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RUNX1 Is a Key Target in t(4;11) Leukemias that Contributes to Gene Activation through an AF4-MLL Complex Interaction von Wilkinson, Adam C., Ballabio, Erica, Geng, Huimin, North, Phillip, Tapia, Marta, Kerry, Jon, Biswas, Debabrata, Roeder, Robert G., Allis, C. David, Melnick, Ari, de Bruijn, Marella F.T.R., Milne, Thomas A.

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The genome-wide impact of trisomy 21 on DNA methylation and its implications for hematopoiesis von Muskens, Ivo S., Li, Shaobo, Jackson, Thomas, Elliot, Natalina, Hansen, Helen M., Myint, Swe Swe, Pandey, Priyatama, Schraw, Jeremy M., Roy, Ritu, Anguiano, Joaquin, Goudevenou, Katerina, Siegmund, Kimberly D., Lupo, Philip J., de Bruijn, Marella F. T. R., Walsh, Kyle M., Vyas, Paresh, Ma, Xiaomei, Roy, Anindita, Roberts, Irene, Wiemels, Joseph L., de Smith, Adam J.

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GATA2 mitotic bookmarking is required for definitive haematopoiesis von Silvério-Alves, Rita, Kurochkin, Ilia, Rydström, Anna, Vazquez Echegaray, Camila, Haider, Jakob, Nicholls, Matthew, Rode, Christina, Thelaus, Louise, Lindgren, Aida Yifter, Ferreira, Alexandra Gabriela, Brandão, Rafael, Larsson, Jonas, de Bruijn, Marella F. T. R., Martin-Gonzalez, Javier, Pereira, Carlos-Filipe

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Characterization of transcriptional networks in blood stem and progenitor cells using high-throughput single-cell gene expression analysis von Moignard, Victoria, Macaulay, Iain C., Swiers, Gemma, Buettner, Florian, Schütte, Judith, Calero-Nieto, Fernando J., Kinston, Sarah, Joshi, Anagha, Hannah, Rebecca, Theis, Fabian J., Jacobsen, Sten Eirik, de Bruijn, Marella F., Göttgens, Berthold

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Dynamic Runx1 chromatin boundaries affect gene expression in hematopoietic development von Owens, Dominic D. G., Anselmi, Giorgio, Oudelaar, A. Marieke, Downes, Damien J., Cavallo, Alessandro, Harman, Joe R., Schwessinger, Ron, Bucakci, Akin, Greder, Lucas, de Ornellas, Sara, Jeziorska, Danuta, Telenius, Jelena, Hughes, Jim R., de Bruijn, Marella F. T. R.

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The T-box transcription factor Eomesodermin governs haemogenic competence of yolk sac mesodermal progenitors von Harland, Luke T. G., Simon, Claire S., Senft, Anna D., Costello, Ita, Greder, Lucas, Imaz-Rosshandler, Ivan, Göttgens, Berthold, Marioni, John C., Bikoff, Elizabeth K., Porcher, Catherine, de Bruijn, Marella F. T. R., Robertson, Elizabeth J.

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Kit ligand has a critical role in mouse yolk sac and aorta–gonad–mesonephros hematopoiesis von Azzoni, Emanuele, Frontera, Vincent, McGrath, Kathleen E, Harman, Joe, Carrelha, Joana, Nerlov, Claus, Palis, James, Jacobsen, Sten Eirik W, de Bruijn, Marella FTR

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Ezh2 is essential for the generation of functional yolk sac derived erythro-myeloid progenitors von Neo, Wen Hao, Meng, Yiran, Rodriguez-Meira, Alba, Fadlullah, Muhammad Z. H., Booth, Christopher A. G., Azzoni, Emanuele, Thongjuea, Supat, de Bruijn, Marella F. T. R., Jacobsen, Sten Eirik W., Mead, Adam J., Lacaud, Georges

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Early dynamic fate changes in haemogenic endothelium characterized at the single-cell level von Swiers, Gemma, Baumann, Claudia, O’Rourke, John, Giannoulatou, Eleni, Taylor, Stephen, Joshi, Anagha, Moignard, Victoria, Pina, Cristina, Bee, Thomas, Kokkaliaris, Konstantinos D., Yoshimoto, Momoko, Yoder, Mervin C., Frampton, Jon, Schroeder, Timm, Enver, Tariq, Göttgens, Berthold, de Bruijn, Marella F. T. R.

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The Origin of Tissue-Resident Macrophages: When an Erythro-myeloid Progenitor Is an Erythro-myeloid Progenitor von Gomez Perdiguero, Elisa, Klapproth, Kay, Schulz, Christian, Busch, Katrin, de Bruijn, Marella, Rodewald, Hans-Reimer, Geissmann, Frederic

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Core-binding factors in hematopoiesis and immune function von de Bruijn, Marella FTR, Speck, Nancy A

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Tracking early mammalian organogenesis - prediction and validation of differentiation trajectories at whole organism scale von Imaz-Rosshandler, Ivan, Rode, Christina, Guibentif, Carolina, Harland, Luke T G, Ton, Mai-Linh N, Dhapola, Parashar, Keitley, Daniel, Argelaguet, Ricard, Calero-Nieto, Fernando J, Nichols, Jennifer, Marioni, John C, de Bruijn, Marella F T R, Göttgens, Berthold

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Runx transcription factors in the development and function of the definitive hematopoietic system von de Bruijn, Marella, Dzierzak, Elaine

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Hematopoietic Reprogramming In Vitro Informs In Vivo Identification of Hemogenic Precursors to Definitive Hematopoietic Stem Cells von Pereira, Carlos-Filipe, Chang, Betty, Gomes, Andreia, Bernitz, Jeffrey, Papatsenko, Dmitri, Niu, Xiaohong, Swiers, Gemma, Azzoni, Emanuele, de Bruijn, Marella F.T.R., Schaniel, Christoph, Lemischka, Ihor R., Moore, Kateri A.

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A KMT2A-AFF1 gene regulatory network highlights the role of core transcription factors and reveals the regulatory logic of key downstream target genes von Harman, Joe R, Thorne, Ross, Jamilly, Max, Tapia, Marta, Crump, Nicholas T, Rice, Siobhan, Beveridge, Ryan, Morrissey, Edward, de Bruijn, Marella F T R, Roberts, Irene, Roy, Anindita, Fulga, Tudor A, Milne, Thomas A

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The onset of circulation triggers a metabolic switch required for endothelial to hematopoietic transition von Azzoni, Emanuele, Frontera, Vincent, Anselmi, Giorgio, Rode, Christina, James, Chela, Deltcheva, Elitza M., Demian, Atanasiu S., Brown, John, Barone, Cristiana, Patelli, Arianna, Harman, Joe R., Nicholls, Matthew, Conway, Simon J., Morrissey, Edward, Jacobsen, Sten Eirik W., Sparrow, Duncan B., Harris, Adrian L., Enver, Tariq, de Bruijn, Marella F.T.R.

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SCL transcriptional network and BMP signaling pathway interact to regulate RUNX1 activity von Pimanda, John E, Donaldson, Ian J, de Bruijn, Marella F.T.R, Kinston, Sarah, Knezevic, Kathy, Huckle, Liz, Piltz, Sandie, Landry, Josette-Renée, Green, Anthony R, Tannahill, David, Göttgens, Berthold

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