Ligand-Based Design of Allosteric Retinoic Acid Receptor-Related Orphan Receptor γt (RORγt) Inverse Agonists von Meijer, Femke A, Doveston, Richard G, de Vries, Rens M.J.M, Vos, Gaël M, Vos, Alex A.A, Leysen, Seppe, Scheepstra, Marcel, Ottmann, Christian, Milroy, Lech-Gustav, Brunsveld, Luc

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Structure–Activity Relationship Studies of Trisubstituted Isoxazoles as Selective Allosteric Ligands for the Retinoic-Acid-Receptor-Related Orphan Receptor γt von Meijer, Femke A, Saris, Annet O.W.M, Doveston, Richard G, Oerlemans, Guido J.M, de Vries, Rens M.J.M, Somsen, Bente A, Unger, Anke, Klebl, Bert, Ottmann, Christian, Cossar, Peter J, Brunsveld, Luc

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Cooperativity between the orthosteric and allosteric ligand binding sites of RORγt von de Vries, Rens M. J. M., Meijer, Femke A., Doveston, Richard G., Leijten-van de Gevel, Iris A., Brunsveld, Luc

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Characterization and small-molecule stabilization of the multisite tandem binding between 14-3-3 and the R domain of CFTR von Stevers, Loes M., Lam, Chan V., Leysen, Seppe F. R., Meijer, Femke A., van Scheppingen, Daphne S., de Vries, Rens M. J. M., Carlile, Graeme W., Milroy, Lech G., Thomas, David Y., Brunsveld, Luc, Ottmann, Christian

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Allosteric small molecule modulators of nuclear receptors von Meijer, Femke A., Leijten-van de Gevel, Iris A., de Vries, Rens M.J.M., Brunsveld, Luc

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Structural interface between LRRK2 and 14-3-3 protein von Stevers, Loes M, de Vries, Rens M J M, Doveston, Richard G, Milroy, Lech-Gustav, Brunsveld, Luc, Ottmann, Christian

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Elucidation of an Allosteric Mode of Action for a Thienopyrazole RORγt Inverse Agonist von Vries, Rens M. J. M., Doveston, Richard G., Meijer, Femke A., Brunsveld, Luc

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Indazole MRL-871 interacts with PPARγ via a binding mode that induces partial agonism von Leijten-van de Gevel, Iris A., van Herk, Kim H.N., de Vries, Rens M.J.M., Ottenheym, Nicolaas J., Ottmann, Christian, Brunsveld, Luc

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Ligand Dependent Switch from RXR Homo- to RXR-NURR1 Heterodimerization von Scheepstra, Marcel, Andrei, Sebastian A, de Vries, Rens M. J. M, Meijer, Femke A, Ma, Jian-Nong, Burstein, Ethan S, Olsson, Roger, Ottmann, Christian, Milroy, Lech-Gustav, Brunsveld, Luc

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