Targeting of epigenetic regulators in neuroblastoma von Jubierre, Luz, Jiménez, Carlos, Rovira, Eric, Soriano, Aroa, Sábado, Constantino, Gros, Luis, Llort, Anna, Hladun, Raquel, Roma, Josep, Toledo, Josep Sánchez de, Gallego, Soledad, Segura, Miguel F.

Volltext

Notch Pathway Inhibition Significantly Reduces Rhabdomyosarcoma Invasiveness and Mobility In Vitro von ROMA, Josep, MASIA, Anna, REVENTOS, Jaume, SANCHEZ DE TOLEDO, Josep, GALLEGO, Soledad

Volltext

Functional high-throughput screening reveals miR-323a-5p and miR-342-5p as new tumor-suppressive microRNA for neuroblastoma von Soriano, Aroa, Masanas, Marc, Boloix, Ariadna, Masiá, Núria, París-Coderch, Laia, Piskareva, Olga, Jiménez, Carlos, Henrich, Kai-Oliver, Roma, Josep, Westermann, Frank, Stallings, Raymond L., Sábado, Constantino, de Toledo, Josep Sánchez, Santamaria, Anna, Gallego, Soledad, Segura, Miguel F.

Volltext

Structural disruption of BAF chromatin remodeller impairs neuroblastoma metastasis by reverting an invasiveness epigenomic program von Jiménez, Carlos, Antonelli, Roberta, Nadal-Ribelles, Mariona, Devis-Jauregui, Laura, Latorre, Pablo, Solé, Carme, Masanas, Marc, Molero-Valenzuela, Adrià, Soriano, Aroa, Sánchez de Toledo, Josep, Llobet-Navas, David, Roma, Josep, Posas, Francesc, de Nadal, Eulàlia, Gallego, Soledad, Moreno, Lucas, Segura, Miguel F

Volltext

Long Non-coding RNA PVT1 as a Prognostic and Therapeutic Target in Pediatric Cancer von Boloix, Ariadna, Masanas, Marc, Jiménez, Carlos, Antonelli, Roberta, Soriano, Aroa, Roma, Josep, Sánchez de Toledo, Josep, Gallego, Soledad, Segura, Miguel F.

Volltext

Neuronal Differentiation-Related Epigenetic Regulator ZRF1 Has Independent Prognostic Value in Neuroblastoma but Is Functionally Dispensable In Vitro von Jimenez, Carlos, Antonelli, Roberta, Masanas, Marc, Soriano, Aroa, Devis-Jauregui, Laura, Camacho, Jessica, Magdaleno, Ainara, Guillen, Gabriela, Hladun, Raquel, Jubierre, Luz, Roma, Josep, Llobet-Navas, David, Sanchez de Toledo, Josep, Moreno, Lucas, Gallego, Soledad, Segura, Miguel F.

Volltext

Engineering pH‐Sensitive Stable Nanovesicles for Delivery of MicroRNA Therapeutics von Boloix, Ariadna, Feiner‐Gracia, Natalia, Köber, Mariana, Repetto, Javier, Pascarella, Rosa, Soriano, Aroa, Masanas, Marc, Segovia, Nathaly, Vargas‐Nadal, Guillem, Merlo‐Mas, Josep, Danino, Dganit, Abutbul‐Ionita, Inbal, Foradada, Laia, Roma, Josep, Córdoba, Alba, Sala, Santi, Toledo, Josep Sánchez, Gallego, Soledad, Veciana, Jaume, Albertazzi, Lorenzo, Segura, Miguel F., Ventosa, Nora

Volltext

The oral KIF11 inhibitor 4SC‐205 exhibits antitumor activity and potentiates standard and targeted therapies in primary and metastatic neuroblastoma models von Masanas, Marc, Masiá, Nuria, Suárez‐Cabrera, Leticia, Olivan, Mireia, Soriano, Aroa, Majem, Blanca, Devis‐Jauregui, Laura, Burgos‐Panadero, Rebeca, Jiménez, Carlos, Rodriguez‐Sodupe, Pau, Boloix, Ariadna, Toledano, Ignasi, Guillén, Gabriela, Navarro, Alexandra, Llobet‐Navas, David, Villanueva, Alberto, Sánchez de Toledo, Josep, Roma, Josep, Noguera, Rosa, Moreno, Lucas, Krauss, Rolf, Gallego, Soledad, Santamaria, Anna, Segura, Miguel F.

Volltext

Integrin alpha9 emerges as a key therapeutic target to reduce metastasis in rhabdomyosarcoma and neuroblastoma von Navarro, Natalia, Molist, Carla, Sansa-Girona, Júlia, Zarzosa, Patricia, Gallo-Oller, Gabriel, Pons, Guillem, Magdaleno, Ainara, Guillén, Gabriela, Hladun, Raquel, Garrido, Marta, Segura, Miguel F., Hontecillas-Prieto, Lourdes, de Álava, Enrique, Ponsati, Berta, Fernández-Carneado, Jimena, Almazán-Moga, Ana, Vallès-Miret, Mariona, Farrera-Sinfreu, Josep, de Toledo, Josep Sánchez, Moreno, Lucas, Gallego, Soledad, Roma, Josep

Volltext

Targeting the Hedgehog Pathway in Rhabdomyosarcoma von Zarzosa, Patricia, Garcia-Gilabert, Lia, Hladun, Raquel, Guillén, Gabriela, Gallo-Oller, Gabriel, Pons, Guillem, Sansa-Girona, Julia, Segura, Miguel F, Sánchez de Toledo, Josep, Moreno, Lucas, Gallego, Soledad, Roma, Josep

Volltext

Analysis of Cancer Genomic Amplifications Identifies Druggable Collateral Dependencies within the Amplicon von Pons, Guillem, Gallo-Oller, Gabriel, Navarro, Natalia, Zarzosa, Patricia, Sansa-Girona, Júlia, García-Gilabert, Lia, Magdaleno, Ainara, Segura, Miguel F, Sánchez de Toledo, Josep, Gallego, Soledad, Moreno, Lucas, Roma, Josep

Volltext

The antitumour drug ABTL0812 impairs neuroblastoma growth through endoplasmic reticulum stress-mediated autophagy and apoptosis von París-Coderch, Laia, Soriano, Aroa, Jiménez, Carlos, Erazo, Tatiana, Muñoz-Guardiola, Pau, Masanas, Marc, Antonelli, Roberta, Boloix, Ariadna, Alfón, José, Pérez-Montoyo, Héctor, Yeste-Velasco, Marc, Domènech, Carles, Roma, Josep, Sánchez de Toledo, Josep, Moreno, Lucas, Lizcano, José M., Gallego, Soledad, Segura, Miguel F.

Volltext

CN133, a Novel Brain-Penetrating Histone Deacetylase Inhibitor, Hampers Tumor Growth in Patient-Derived Pediatric Posterior Fossa Ependymoma Models von Antonelli, Roberta, Jimenez, Carlos, Riley, Misha, Servidei, Tiziana, Riccardi, Riccardo, Soriano, Aroa, Roma, Josep, Martinez-Saez, Elena, Martini, Maurizio, Ruggiero, Antonio, Moreno, Lucas, Sanchez de Toledo, Josep, Gallego, Soledad, Bove, Jordi, Hooker, Jacob M., Segura, Miguel F.

Volltext

Optimization of rhabdomyosarcoma disseminated disease assessment by flow cytometry von Almazán‐Moga, Ana, Roma, Josep, Molist, Carla, Vidal, Isaac, Jubierre, Luz, Soriano, Aroa, Segura, Miguel Francisco, Llort, Anna, Sánchez de Toledo, Josep, Gallego, Soledad

Volltext

Notch, Wnt, and Hedgehog Pathways in Rhabdomyosarcoma: From Single Pathways to an Integrated Network von Roma, Josep, Almazán-Moga, Anna, Sánchez de Toledo, Josep, Gallego, Soledad

Volltext

EPEN-07. Brain-tumor communication reveals potential new therapeutic targets for pediatric ependymoma von Antonelli, Roberta, Jiménez, Carlos, Servidei, Tiziana, Riccardi, Riccardo, Martínez-Saez, Elena, de Toledo, Josep Sánchez, Roma, Josep, Gallego, Soledad, Llort, Anna, Moreno, Lucas, Segura, Miguel

Volltext

Engineering pH-Sensitive Stable Nanovesicles for Delivery of MicroRNA Therapeutics von Boloix, Ariadna, Feiner Gracia, Natalia, Kober, Marina, Repetto, Javier, Pascarella, Rosa, Soriano, Aroa, Masanas, Marc, Segovia, Nathaly, Vargas Nadal, Guillem, Merlo Mas, Josep, Danino, Dganit, Abutbul-Ionita, Inbal, Foradada, Laia, Roma, Josep, Cordoba, Alba, Sala, Santi, Sánchez de Toledo, Josep, Gallego Melcón, Soledad, Veciana, Jaume, Albertazzi, Lorenzo, Segura, Miguel F, Ventosa, Nora

Volltext

Characterisation of novel splicing variants of the tyrosine hydroxylase C-terminal domain in human neuroblastic tumours von Roma, Josep, Saus, Ester, Cuadros, Marc, Reventós, Jaume, Sánchez de Toledo, Josep, Gallego, Soledad

Volltext

Structural disruption of BAF chromatin remodeller impairs neuroblastoma metastasis by reverting an invasiveness epigenomic program von Jiménez, Carlos, Antonelli, Roberta, Nadal Ribelles, Mariona, Devis Jauregui, Laura, Latorre, Pablo, Solé, Carme, Masanas, Marc, Molero Valenzuela, Adrià, Soriano, Aroa, Sánchez De Toledo, Josep, Llobet Navas, David, Roma, Josep, Posas, Francesc, De Nadal, Eulàlia, Gallego, Soledad, Moreno, Lucas, Segura, Miguel F

Volltext

Structural disruption of BAF chromatin remodeller impairs neuroblastoma metastasis by reverting an invasiveness epigenomic program von Jiménez, Carlos, Antonelli, Roberta, Nadal Ribelles, Mariona, 1984, Devis-Jauregui, Laura, Latorre Doménech, Pablo, 1993, Solé, Carme, Masanas, Marc, Molero-Valenzuela, Adrià, Soriano, Aroa, Sánchez de Toledo, Josep, Llobet-Navas, David, Roma, Josep, Posas Garriga, Francesc, Nadal Clanchet, Eulàlia de, Gallego, Soledad, Moreno, Lucas, Segura, Miguel F

Volltext