Targeting Ergosterol Biosynthesis in Leishmania donovani: Essentiality of Sterol 14alpha-demethylase von McCall, Laura-Isobel, Aroussi, Amale El, Choi, Jun Yong, Vieira, Debora F, De Muylder, Geraldine, Johnston, Jonathan B, Chen, Steven, Kellar, Danielle, Siqueira-Neto, Jair L, Roush, William R, Podust, Larissa M, McKerrow, James H

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Discovery of New Zika Protease and Polymerase Inhibitors through the Open Science Collaboration Project OpenZika von Mottin, Melina, de Paula Sousa, Bruna Katiele, de Moraes Roso Mesquita, Nathalya Cristina, de Oliveira, Ketllyn Irene Zagato, Noske, Gabriela Dias, Sartori, Geraldo Rodrigues, de Oliveira Albuquerque, Aline, Urbina, Fabio, Puhl, Ana C., Moreira-Filho, José Teófilo, Souza, Guilherme E., Guido, Rafael V. C., Muratov, Eugene, Neves, Bruno Junior, Martins da Silva, João Hermínio, Clark, Alex E., Siqueira-Neto, Jair L., Perryman, Alexander L., Oliva, Glaucius, Ekins, Sean, Andrade, Carolina Horta

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The Leishmania amazonensis TRF (TTAGGG repeat-binding factor) homologue binds and co-localizes with telomeres von da Silva, Marcelo S, Perez, Arina M, da Silveira, Rita de Cássia V, de Moraes, Camila E, Siqueira-Neto, Jair L, Freitas, Jr, Lucio de H, Cano, Maria Isabel N

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LaTBP1: A Leishmania amazonensis DNA-binding protein that associates in vivo with telomeres and GT-rich DNA using a Myb-like domain von Lira, Cristina B.B., de Siqueira Neto, Jair L., Khater, Letícia, Cagliari, Thiago C., Peroni, Luis A., dos Reis, José R.R., Ramos, Carlos H.I., Cano, Maria I.N.

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putative telomerase reverse transcriptase component of Leishmania amazonensis: gene cloning and characterization von Giardini, Miriam A, Lira, Cristina B. B, Conte, Fábio F, Camillo, Luciana R, de Siqueira Neto, Jair L, Ramos, Carlos H. I, Cano, Maria Isabel N

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Automated nuclear analysis of Leishmania major telomeric clusters reveals changes in their organization during the parasite's life cycle von Dossin, Fernando de M, Dufour, Alexandre, Dusch, Elodie, Siqueira-Neto, Jair L, Moraes, Carolina B, Yang, Gyong Seon, Cano, Maria Isabel, Genovesio, Auguste, Freitas-Junior, Lucio H

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The Leishmania amazonensis TRF von da Silva, Marcelo S, Perez, Arina M, da Silveira, Rita de Cássia V, de Moraes, Camila E, Siqueira-Neto, Jair L, Freitas, Lucio de H., Junior, Cano, Maria Isabel N

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Cysteine proteases in protozoan parasites von Siqueira-Neto, Jair L, Debnath, Anjan, McCall, Laura-Isobel, Bernatchez, Jean A, Ndao, Momar, Reed, Sharon L, Rosenthal, Philip J

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Spatial metabolomics identifies localized chemical changes in heart tissue during chronic cardiac Chagas Disease von Dean, Danya A, Gautham, Gautham, Siqueira-Neto, Jair L, McKerrow, James H, Dorrestein, Pieter C, McCall, Laura-Isobel

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Drugs for the Treatment of Zika Virus Infection von Bernatchez, Jean A, Tran, Lana T, Li, Jerry, Luan, Yepeng, Siqueira-Neto, Jair L, Li, Rongshi

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Experimental Chagas disease-induced perturbations of the fecal microbiome and metabolome von McCall, Laura-Isobel, Tripathi, Anupriya, Vargas, Fernando, Knight, Rob, Dorrestein, Pieter C, Siqueira-Neto, Jair L

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Machine Learning Models and Pathway Genome Data Base for Trypanosoma cruzi Drug Discovery von Ekins, Sean, de Siqueira-Neto, Jair Lage, McCall, Laura-Isobel, Sarker, Malabika, Yadav, Maneesh, Ponder, Elizabeth L, Kallel, E Adam, Kellar, Danielle, Chen, Steven, Arkin, Michelle, Bunin, Barry A, McKerrow, James H, Talcott, Carolyn

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Coumarin-based derivatives targeting Trypanosoma cruzi cruzain and Trypanosoma brucei cathepsin L-like proteases von Nunes, Jéssica Alves, Silva, Fabrícia Nunes da, Silva, Elany Barbosa da, Costa, Clara Andrezza Crisóstomo Bezerra, Freitas, Johnnatan Duarte de, Mendonça-Junior, Francisco Jaime Bezerra, Giardini, Miriam Aparecida, Siqueira-Neto, Jair Lage de, McKerrow, James H., Rodrigues Teixeira, Thaiz, Odeesho, Louis William, Caffrey, Conor R., Cardoso, Sílvia Helena, Silva-Júnior, Edeildo Ferreira da

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Antimalarial drug discovery: progress and approaches von Siqueira-Neto, Jair L., Wicht, Kathryn J., Chibale, Kelly, Burrows, Jeremy N., Fidock, David A., Winzeler, Elizabeth A.

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Location, Location, Location: Five Facts about Tissue Tropism and Pathogenesis von McCall, Laura-Isobel, Siqueira-Neto, Jair L, McKerrow, James H

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Molecular dissection of Chagas induced cardiomyopathy reveals central disease associated and druggable signaling pathways von Wozniak, Jacob M, Silva, Tatiana Araújo, Thomas, Diane, Siqueira-Neto, Jair L, McKerrow, James H, Gonzalez, David J, Calvet, Claudia M

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An image-based high-content screening assay for compounds targeting intracellular Leishmania donovani amastigotes in human macrophages von Siqueira-Neto, Jair L, Moon, Seunghyun, Jang, Jiyeon, Yang, Gyongseon, Lee, Changbok, Moon, Hong Kee, Chatelain, Eric, Genovesio, Auguste, Cechetto, Jonathan, Freitas-Junior, Lucio H

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Palstimolide A: A Complex Polyhydroxy Macrolide with Antiparasitic Activity von Keller, Lena, Siqueira-Neto, Jair L, Souza, Julia M, Eribez, Korina, LaMonte, Gregory M, Smith, Jennifer E, Gerwick, William H

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Antileishmanial high-throughput drug screening reveals drug candidates with new scaffolds von Siqueira-Neto, Jair L, Song, Ok-Ryul, Oh, Hyunrim, Sohn, Jeong-Hun, Yang, Gyongseon, Nam, Jiyoun, Jang, Jiyeon, Cechetto, Jonathan, Lee, Chang Bok, Moon, Seunghyun, Genovesio, Auguste, Chatelain, Eric, Christophe, Thierry, Freitas-Junior, Lucio H

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Genome-scale metabolic models highlight stage-specific differences in essential metabolic pathways in Trypanosoma cruzi von Shiratsubaki, Isabel S, Fang, Xin, Souza, Rodolpho O O, Palsson, Bernhard O, Silber, Ariel M, Siqueira-Neto, Jair L

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