Lgr5+ Stem Cells Are Indispensable for Radiation-Induced Intestinal Regeneration von Metcalfe, Ciara, Kljavin, Noelyn M., Ybarra, Ryan, de Sauvage, Frederic J.

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Parasitic helminths induce fetal-like reversion in the intestinal stem cell niche von Nusse, Ysbrand M., Savage, Adam K., Marangoni, Pauline, Rosendahl-Huber, Axel K. M., Landman, Tyler A., de Sauvage, Frederic J., Locksley, Richard M., Klein, Ophir D.

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Genomic Analysis of Smoothened Inhibitor Resistance in Basal Cell Carcinoma von Sharpe, Hayley J., Pau, Gregoire, Dijkgraaf, Gerrit J., Basset-Seguin, Nicole, Modrusan, Zora, Januario, Thomas, Tsui, Vickie, Durham, Alison B., Dlugosz, Andrzej A., Haverty, Peter M., Bourgon, Richard, Tang, Jean Y., Sarin, Kavita Y., Dirix, Luc, Fisher, David C., Rudin, Charles M., Sofen, Howard, Migden, Michael R., Yauch, Robert L., de Sauvage, Frederic J.

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Lgr5+ telocytes are a signaling source at the intestinal villus tip von Bahar Halpern, Keren, Massalha, Hassan, Zwick, Rachel K., Moor, Andreas E., Castillo-Azofeifa, David, Rozenberg, Milena, Farack, Lydia, Egozi, Adi, Miller, Dan R., Averbukh, Inna, Harnik, Yotam, Weinberg-Corem, Noa, de Sauvage, Frederic J., Amit, Ido, Klein, Ophir D., Shoshkes-Carmel, Michal, Itzkovitz, Shalev

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Opposing Activities of Notch and Wnt Signaling Regulate Intestinal Stem Cells and Gut Homeostasis von Tian, Hua, Biehs, Brian, Chiu, Cecilia, Siebel, Christian W., Wu, Yan, Costa, Mike, de Sauvage, Frederic J., Klein, Ophir D.

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IL-27 Regulates IL-12 Responsiveness of naïve CD4+T Cells through Stat1-Dependent and -Independent Mechanisms von Lucas, Sophie, Ghilardi, Nico, Li, Ji, de Sauvage, Frédéric J.

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Cellular Plasticity in Intestinal Homeostasis and Disease von de Sousa e Melo, Felipe, de Sauvage, Frederic J.

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A distinct role for Lgr5+ stem cells in primary and metastatic colon cancer von de Sousa e Melo, Felipe, Kurtova, Antonina V., Harnoss, Jonathan M., Kljavin, Noelyn, Hoeck, Joerg D., Hung, Jeffrey, Anderson, Jeffrey Eastham, Storm, Elaine E., Modrusan, Zora, Koeppen, Hartmut, Dijkgraaf, Gerrit J. P., Piskol, Robert, de Sauvage, Frederic J.

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Tissue regeneration: Reserve or reverse? von Shivdasani, Ramesh A, Clevers, Hans, de Sauvage, Frederic J

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Hedgehog Fights Back: Mechanisms of Acquired Resistance against Smoothened Antagonists von METCALFE, Ciara, DE SAUVAGE, Frederic J

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Mechanisms of Hedgehog pathway activation in cancer and implications for therapy von Scales, Suzie J, de Sauvage, Frederic J

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Distinct Mesenchymal Cell Populations Generate the Essential Intestinal BMP Signaling Gradient von McCarthy, Neil, Manieri, Elisa, Storm, Elaine E., Saadatpour, Assieh, Luoma, Adrienne M., Kapoor, Varun N., Madha, Shariq, Gaynor, Liam T., Cox, Christian, Keerthivasan, Shilpa, Wucherpfennig, Kai, Yuan, Guo-Cheng, de Sauvage, Frederic J., Turley, Shannon J., Shivdasani, Ramesh A.

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The great escape: tumour cell plasticity in resistance to targeted therapy von Boumahdi, Soufiane, de Sauvage, Frederic J.

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Comprehensive genomic analysis of malignant pleural mesothelioma identifies recurrent mutations, gene fusions and splicing alterations von Bueno, Raphael, Stawiski, Eric W, Goldstein, Leonard D, Durinck, Steffen, De Rienzo, Assunta, Modrusan, Zora, Gnad, Florian, Nguyen, Thong T, Jaiswal, Bijay S, Chirieac, Lucian R, Sciaranghella, Daniele, Dao, Nhien, Gustafson, Corinne E, Munir, Kiara J, Hackney, Jason A, Chaudhuri, Amitabha, Gupta, Ravi, Guillory, Joseph, Toy, Karen, Ha, Connie, Chen, Ying-Jiun, Stinson, Jeremy, Chaudhuri, Subhra, Zhang, Na, Wu, Thomas D, Sugarbaker, David J, de Sauvage, Frederic J, Richards, William G, Seshagiri, Somasekar

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Development of Th1-type immune responses requires the type I cytokine receptor TCCR von QI CHEN, GHILARDL, Nico, HUA WANG, BAKER, Thad, XIE, Ming-Hong, GURNEY, Austin, GREWAL, Iqbal S, DE SAUVAGE, Fredertc J

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Genomic analysis identifies new drivers and progression pathways in skin basal cell carcinoma von Bonilla, Ximena, Parmentier, Laurent, King, Bryan, Bezrukov, Fedor, Kaya, Gürkan, Zoete, Vincent, Seplyarskiy, Vladimir B, Sharpe, Hayley J, McKee, Thomas, Letourneau, Audrey, Ribaux, Pascale G, Popadin, Konstantin, Basset-Seguin, Nicole, Chaabene, Rouaa Ben, Santoni, Federico A, Andrianova, Maria A, Guipponi, Michel, Garieri, Marco, Verdan, Carole, Grosdemange, Kerstin, Sumara, Olga, Eilers, Martin, Aifantis, Iannis, Michielin, Olivier, de Sauvage, Frederic J, Antonarakis, Stylianos E, Nikolaev, Sergey I

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Recurrent R-spondin fusions in colon cancer von Seshagiri, Somasekar, Stawiski, Eric W., Durinck, Steffen, Modrusan, Zora, Storm, Elaine E., Conboy, Caitlin B., Chaudhuri, Subhra, Guan, Yinghui, Janakiraman, Vasantharajan, Jaiswal, Bijay S., Guillory, Joseph, Ha, Connie, Dijkgraaf, Gerrit J. P., Stinson, Jeremy, Gnad, Florian, Huntley, Melanie A., Degenhardt, Jeremiah D., Haverty, Peter M., Bourgon, Richard, Wang, Weiru, Koeppen, Hartmut, Gentleman, Robert, Starr, Timothy K., Zhang, Zemin, Largaespada, David A., Wu, Thomas D., de Sauvage, Frederic J.

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Atoh1+ secretory progenitors possess renewal capacity independent of Lgr5+ cells during colonic regeneration von Castillo‐Azofeifa, David, Fazio, Elena N, Nattiv, Roy, Good, Hayley J, Wald, Tomas, Pest, Michael A, de Sauvage, Frederic J, Klein, Ophir D, Asfaha, Samuel

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Spectrum of diverse genomic alterations define non–clear cell renal carcinoma subtypes von Durinck, Steffen, Stawiski, Eric W, Pavía-Jiménez, Andrea, Modrusan, Zora, Kapur, Payal, Jaiswal, Bijay S, Zhang, Na, Toffessi-Tcheuyap, Vanina, Nguyen, Thong T, Pahuja, Kanika Bajaj, Chen, Ying-Jiun, Saleem, Sadia, Chaudhuri, Subhra, Heldens, Sherry, Jackson, Marlena, Peña-Llopis, Samuel, Guillory, Joseph, Toy, Karen, Ha, Connie, Harris, Corissa J, Holloman, Eboni, Hill, Haley M, Stinson, Jeremy, Rivers, Celina Sanchez, Janakiraman, Vasantharajan, Wang, Weiru, Kinch, Lisa N, Grishin, Nick V, Haverty, Peter M, Chow, Bernard, Gehring, Julian S, Reeder, Jens, Pau, Gregoire, Wu, Thomas D, Margulis, Vitaly, Lotan, Yair, Sagalowsky, Arthur, Pedrosa, Ivan, de Sauvage, Frederic J, Brugarolas, James, Seshagiri, Somasekar

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Efficacy of Hedgehog pathway inhibitors in Basal cell carcinoma von Basset-Seguin, Nicole, Sharpe, Hayley J, de Sauvage, Frederic J

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