SIRT1 and SIRT2 inhibition impairs pediatric soft tissue sarcoma growth von Ma, L, Maruwge, W, Strambi, A, D'Arcy, P, Pellegrini, P, Kis, L, de Milito, A, Lain, S, Brodin, B

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Effect of Proton Pump Inhibitor Pretreatment on Resistance of Solid Tumors to Cytotoxic Drugs von Luciani, Francesca, Spada, Massimo, De Milito, Angelo, Molinari, Agnese, Rivoltini, Licia, Montinaro, Annalisa, Marra, Manuela, Lugini, Luana, Logozzi, Mariantonia, Lozupone, Francesco, Federici, Cristina, Iessi, Elisabetta, Parmiani, Giorgio, Arancia, Giuseppe, Belardelli, Filippo, Fais, Stefano

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Proton pump inhibition induces autophagy as a survival mechanism following oxidative stress in human melanoma cells von Marino, M L, Fais, S, Djavaheri-Mergny, M, Villa, A, Meschini, S, Lozupone, F, Venturi, G, Della Mina, P, Pattingre, S, Rivoltini, L, Codogno, P, De Milito, A

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Therapeutic implications of tumor interstitial acidification von Kolosenko, Iryna, Avnet, Sofia, Baldini, Nicola, Viklund, Jenny, De Milito, Angelo

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Modulation of Microenvironment Acidity Reverses Anergy in Human and Murine Tumor-Infiltrating T Lymphocytes von CALCINOTTO, Arianna, FILIPAZZI, Paola, HUBER, Veronica, PARMIANI, Giorgio, GENEROSO, Luca, SANTINAMI, Mario, BORGHI, Martina, FAIS, Stefano, BELLONE, Matteo, RIVOLTINI, Licia, GRIONI, Matteo, LERO, Manuela, DE MILITO, Angelo, RICUPITO, Alessia, COVA, Agata, CANESE, Rossella, JACHETTI, Elena, ROSSETTI, Monica

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Proton channels and exchangers in cancer von Spugnini, Enrico Pierluigi, Sonveaux, Pierre, Stock, Christian, Perez-Sayans, Mario, De Milito, Angelo, Avnet, Sofia, Garcìa, Abel Garcìa, Harguindey, Salvador, Fais, Stefano

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The Role of Autophagy in the Maintenance of Stemness and Differentiation of Mesenchymal Stem Cells von Sbrana, Francesca Vittoria, Cortini, Margherita, Avnet, Sofia, Perut, Francesca, Columbaro, Marta, De Milito, Angelo, Baldini, Nicola

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Inhibition of Vps34 reprograms cold into hot inflamed tumors and improves anti-PD-1/PD-L1 immunotherapy von Noman, Muhammad Zaeem, Parpal, Santiago, Van Moer, Kris, Xiao, Malina, Yu, Yasmin, Viklund, Jenny, De Milito, Angelo, Hasmim, Meriem, Andersson, Martin, Amaravadi, Ravi K., Martinsson, Jessica, Berchem, Guy, Janji, Bassam

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Lighting up the fire in cold tumors to improve cancer immunotherapy by blocking the activity of the autophagy-related protein PIK3C3/VPS34 von Janji, Bassam, Hasmim, Meriem, Parpal, Santiago, De Milito, Angelo, Berchem, Guy, Noman, Muhammad Zaeem

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Soluble CD27 induces IgG production through activation of antigen-primed B cells von Dang, L. V. P., Nilsson, A., Ingelman-Sundberg, H., Cagigi, A., Gelinck, L. B. S., Titanji, K., De Milito, A., Grutzmeier, S., Hedlund, J., Kroon, F. P., Chiodi, F.

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Induction of mitochondrial dysfunction as a strategy for targeting tumour cells in metabolically compromised microenvironments von Zhang, Xiaonan, Fryknäs, Mårten, Hernlund, Emma, Fayad, Walid, De Milito, Angelo, Olofsson, Maria Hägg, Gogvadze, Vladimir, Dang, Long, Påhlman, Sven, Schughart, Leoni A. Kunz, Rickardson, Linda, D′Arcy, Padraig, Gullbo, Joachim, Nygren, Peter, Larsson, Rolf, Linder, Stig

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Cisplatin resistance can be curtailed by blunting Bnip3-mediated mitochondrial autophagy von Vianello, Caterina, Cocetta, Veronica, Catanzaro, Daniela, Dorn, Gerald W, De Milito, Angelo, Rizzolio, Flavio, Canzonieri, Vincenzo, Cecchin, Erika, Roncato, Rossana, Toffoli, Giuseppe, Quagliariello, Vincenzo, Di Mauro, Annabella, Losito, Simona, Maurea, Nicola, Scaffa, Cono, Sales, Gabriele, Scorrano, Luca, Giacomello, Marta, Montopoli, Monica

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Targeting Mitochondrial Function to Treat Quiescent Tumor Cells in Solid Tumors von Zhang, Xiaonan, de Milito, Angelo, Olofsson, Maria Hägg, Gullbo, Joachim, D'Arcy, Padraig, Linder, Stig

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Proton pump inhibitors induce apoptosis of human B-cell tumors through a caspase-independent mechanism involving reactive oxygen species von De Milito, Angelo, Iessi, Elisabetta, Logozzi, Mariantonia, Lozupone, Francesco, Spada, Massimo, Marino, Maria Lucia, Federici, Cristina, Perdicchio, Maurizio, Matarrese, Paola, Lugini, Luana, Nilsson, Anna, Fais, Stefano

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Spheroid‐based 3D cell cultures identify salinomycin as a promising drug for the treatment of chondrosarcoma von Perut, Francesca, Sbrana, Francesca V., Avnet, Sofia, De Milito, Angelo, Baldini, Nicola

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The role of FAS to ezrin association in FAS-mediated apoptosis von Fais, S, De Milito, A, Lozupone, F

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The acidity of the tumor microenvironment is a mechanism of immune escape that can be overcome by proton pump inhibitors von Bellone, Matteo, Calcinotto, Arianna, Filipazzi, Paola, De Milito, Angelo, Fais, Stefano, Rivoltini, Licia

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P-glycoprotein binds to ezrin at amino acid residues 149-242 in the FERM domain and plays a key role in the multidrug resistance of human osteosarcoma von Brambilla, Daria, Zamboni, Silvia, Federici, Cristina, Lugini, Luana, Lozupone, Francesco, Milito, Angelo De, Cecchetti, Serena, Cianfriglia, Maurizio, Fais, Stefano

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Loss of memory B cells impairs maintenance of long-term serologic memory during HIV-1 infection von Titanji, Kehmia, De Milito, Angelo, Cagigi, Alberto, Thorstensson, Rigmor, Grützmeier, Sven, Atlas, Ann, Hejdeman, Bo, Kroon, Frank P., Lopalco, Lucia, Nilsson, Anna, Chiodi, Francesca

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STAT3 is activated in multicellular spheroids of colon carcinoma cells and mediates expression of IRF9 and interferon stimulated genes von Edsbäcker, Elin, Serviss, Jason T., Kolosenko, Iryna, Palm-Apergi, Caroline, De Milito, Angelo, Tamm, Katja Pokrovskaja

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