412P Phase I study of intraperitoneal irinotecan in combination with standard systemic chemotherapy in patients with extensive peritoneal metastases of colorectal origin: The INTER... von Van Eerden, R.A.G., De Boer, N.L., van Kooten, J.P., Bakkers, C., Dietz, M.V., Creemers, G-J.M., Buijs, S.M., Bax, R., de Man, F.M., Lurvink, R.J., Diepeveen, M., Brandt-Kerkhof, A.R.M., van Meerten, E., Koolen, S.L., de Hingh, I.H.J.T., Verhoef, K., Mathijssen, R.H., Burger, P.W.A.

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Efficacy and toxicity of weekly carboplatin and paclitaxel as induction or palliative treatment in advanced esophageal cancer patients von de Man, F.M., Van Eerden, R.A.G., Oomen-de Hoop, E., Veraart, J.N., van Doorn, N., van Doorn, L., van der Gaast, A., Mathijssen, R.H.J.

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782P - Efficacy and toxicity of weekly carboplatin and paclitaxel as induction or palliative treatment in advanced esophageal cancer patients von de Man, F.M., Van Eerden, R.A.G., Oomen-de Hoop, E., Veraart, J.N., van Doorn, N., van Doorn, L., van der Gaast, A., Mathijssen, R.H.J.

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1913P - Effects of dietary restriction in cancer patients receiving irinotecan von Van Eerden, R.A.G., de Man, F.M., van Doorn, G.M., Oomen-de Hoop, E., Koolen, S.L., Olieman, J.F., de Bruijn, P., Veraart, J.N., van Halteren, H.K., Sandberg, Y., Moelker, A., IJzermans, J.N.M., Lolkema, M.P., van Gelder, T., Dollé, M.E.T., de Bruin, R.W.F., Mathijssen, R.H.J.

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Effects of dietary restriction in cancer patients receiving irinotecan von Van Eerden, R.A.G., de Man, F.M., van Doorn, G.M., Oomen-de Hoop, E., Koolen, S.L., Olieman, J.F., de Bruijn, P., Veraart, J.N., van Halteren, H.K., Sandberg, Y., Moelker, A., IJzermans, J.N.M., Lolkema, M.P., van Gelder, T., Dollé, M.E.T., de Bruin, R.W.F., Mathijssen, R.H.J.

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Prospective analysis in GIST patients on the role of alpha-1 acid glycoprotein (AGP) in imatinib exposure von Bins, S., Eechoute, K., Kloth, J.S.L., de Man, F.M., Oosten, A., de Bruijn, P., Sleijfer, S., Mathijssen, R.

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Influence of the proton pump inhibitor esomeprazole on the bioavailability of regorafenib von de Man, F M, Hussaarts, K G A M, de With, M, Oomen-De Hoop, E, van Halteren, H K, van der Burg-De Graauw, N C H P, Eskens, F A L M, van Gelder, T, van Leeuwen, R W F, Mathijssen, R H J

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DPYD genotype-guided dose individualization of fluoropyrimidine therapy: A prospective safety and cost-analysis on DPYD variants DPYD2A, c.2846A>T, c.1679T>G and c.1236G>A von Henricks, L M, Lunenburg, C A T C, de Man, F M, Meulendijks, D, Frederix, G W J, Kienhuis, E, Creemers, G-J M, Baars, A, Dezentjé, V O, Rosing, H, Beijnen, J H, van Werkhoven, E, van Kuilenburg, A B P, van Schaik, R H N, Mathijssen, R H J, Swen, J J, Gelderblom, H, Cats, A, Guchelaar, H-J, Schellens, J H M

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Discovering novel germline genetic variants linked to severe fluoropyrimidine-related toxicity in- and outside DPYD von Knikman, J.E., Zhai, Q.L., Lunenburg, C.A.T.C., Henricks, L.M., Boehringer, S., Lee, M. van der, Man, F.M. de, Offer, S.M., Shrestha, S., Creemers, G.J., Baars, A., Dezentje, V.O., Imholz, A.L.T., Jeurissen, F.J.F., Portielje, J.E.A., Jansen, R.L.H., Hamberg, P., Droogendijk, H.J., Koopman, M., Nieboer, P., Poel, M.H.W. van de, Mandigers, C.M.P.W., Schaik, R.H.N. van, Gelderblom, H., Mathijssen, R.H.J., Schellens, J.H.M., Cats, A., Guchelaar, H.J., Swen, J.J.

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Survival of patients with cancer with DPYD variant alleles and dose-individualized fluoropyrimidine therapy: a matched-pair analysis von Knikman, J.E., Wilting, T.A., Lopez-Yurda, M., Henricks, L.M., Lunenburg, C.A.T.C., Man, F.M. de, Meulendijks, D., Nieboer, P., Droogendijk, H.J., Creemers, G.J., Mandigers, C.M.P.W., Imholz, A.L.T., Mathijssen, R.H.J., Portielje, J.E.A., Valkenburg-van Iersel, L., Vulink, A., Poel, M.H.W. van der, Baars, A., Swen, J.J., Gelderblom, H., Schellens, J.H.M., Beijnen, J.H., Guchelaar, H.J., Cats, A.

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Dihydropyrimidine dehydrogenase phenotyping using pretreatment uracil: a note of caution based on a large prospective clinical study von With, M. de, Knikman, J., Man, F.M. de, Lunenburg, C.A.T.C., Henricks, L.M., Kuilenburg, A.B.P. van, Maring, J.G., Staveren, M.C. van, Vries, N. de, Rosing, H., Beijnen, J.H., Pluim, D., Modak, A., Imholz, A.L.T., Schaik, R.H.N. van, Schellens, J.H.M., Gelderblom, H., Cats, A., Guchelaar, H.J., Mathijssen, R.H.J., Swen, J.J., Meulendijks, D.

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UGT1A1 genotype-guided dosing of irinotecan: a prospective safety and cost analysis in poor metaboliser patients von Hulshof, E.C., With, M. de, Man, F.M. de, Creemers, G.J., Deiman, B.A.L.M., Swen, J.J., Houterman, S., Koolen, S.L.W., Bins, S., Thijs, A.M.J., Laven, M.M.J., Hovels, A.M., Luelmo, S.A.C., Houtsma, D., Shulman, K., McLeod, H.L., Schaik, R.H.N. van, Guchelaar, H.J., Mathijssen, R.H.J., Gelderblom, H., Deenen, M.J.

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A cost analysis of upfront DPYD genotype-guided dose individualisation in fluoropyrimidine-based anticancer therapy von Henricks, L.M., Lunenburg, C.A.T.C., Man, F.M. de, Meulendijks, D., Frederix, G.W.J., Kienhuis, E., Creemers, G.J., Baars, A., Dezentjé, V.O., Imholz, A.L.T., Jeurissen, F.J.F., Portielje, J.E.A., Jansen, R.L.H., Hamberg, P., Tije, A.J. ten, Droogendijk, H.J., Koopman, M., Nieboer, P., Poel, M.H.W. van de, Mandigers, C.M.P.W., Rosing, H., Beijnen, J.H., Werkhoven, E. van, Kuilenburg, A.B.P. van, Schaik, R.H.N. van, Mathijssen, R.H.J., Swen, J.J., Gelderblom, H., Cats, A., Guchelaar, H.J., Schellens, J.H.M.

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Quantitative assessment of infection risk from exposure to waterborne pathogens in urban floodwater von de Man, H., van den Berg, H.H.J.L., Leenen, E.J.T.M., Schijven, J.F., Schets, F.M., van der Vliet, J.C., van Knapen, F., de Roda Husman, A.M.

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Transarterial Chemoembolization With Drug-Eluting Beads Versus Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma: Outcomes From a Multicenter, Randomized, Phase 2 Tr... von Méndez Romero, Alejandra, van der Holt, Bronno, Willemssen, Francois E J A, de Man, Rob A, Heijmen, Ben J M, Habraken, Steven, Westerveld, Henrike, van Delden, Otto M, Klümpen, Heinz-Josef, Tjwa, Eric T T L, Braam, Pètra M, Jenniskens, Sjoerd F M, Vanwolleghem, Thomas, Weytjens, Reinhilde, d'Archambeau, Olivier, de Vos-Geelen, Judith, Buijsen, Jeroen, van der Leij, Christiaan, den Toom, Wilhelm, Sprengers, Dave, IJzermans, Jan N M, Moelker, Adriaan

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Management of hepatocellular adenoma during pregnancy von Noels, Johanna E, van Aalten, Susanna M, van der Windt, Dirk J, Kok, Niels F.M, de Man, Rob A, Terkivatan, Turkan, IJzermans, Jan N.M

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Evolution of CT findings after anticoagulant treatment for acute pulmonary embolism in patients with and without an ultimate diagnosis of chronic thromboembolic pulmonary hypertens... von Braams, Natalia J., Boon, Gudula J. A. M., de Man, Frances S., van Es, Josien, den Exter, Paul L., Kroft, Lucia J. M., Beenen, Ludo F. M., Huisman, Menno, Nossent, Esther J., Boonstra, Anco, Noordegraaf, Anton Vonk, Ruigrok, Dieuwertje, Klok, Frederikus A., Bogaard, Harm Jan, Meijboom, Lilian J.

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Clinical Expression of Leber Hereditary Optic Neuropathy Is Affected by the Mitochondrial DNA–Haplogroup Background von Hudson, Gavin, Carelli, Valerio, Spruijt, Liesbeth, Gerards, Mike, Mowbray, Catherine, Achilli, Alessandro, Pyle, Angela, Elson, Joanna, Howell, Neil, La Morgia, Chiara, Valentino, Maria Lucia, Huoponen, Kirsi, Savontaus, Marja-Liisa, Nikoskelainen, Eeva, Sadun, Alfredo A., Salomao, Solange R., Belfort, Rubens, Griffiths, Philip, Man, Patrick Yu Wai, de Coo, Rene F.M., Horvath, Rita, Zeviani, Massimo, Smeets, Hubert J.T., Torroni, Antonio, Chinnery, Patrick F.

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Embedding routine health care data in clinical trials: with great power comes great responsibility von Handoko, M. Louis, de Man, Frances S., Brugts, Jasper J., van der Meer, Peter, Rhodius-Meester, Hanneke F. M., Schaap, Jeroen, van de Kamp, H. J. Rik, Houterman, Saskia, van Veghel, Dennis, Uijl, Alicia, Asselbergs, Folkert W.

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Toxicity and efficacy of flat-dosed versus body-surface area (BSA)-dosed capecitabine von Man, F.M., Veerman, G.D., Oomen-De Hoop, E., Meerten, E., van Gelder, T., Mathijssen, R.H.J.

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