The digestive tract as the origin of systemic inflammation von de Jong, Petrus R, González-Navajas, José M, Jansen, Nicolaas J G

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ERK5 signalling rescues intestinal epithelial turnover and tumour cell proliferation upon ERK1/2 abrogation von de Jong, Petrus R., Taniguchi, Koji, Harris, Alexandra R., Bertin, Samuel, Takahashi, Naoki, Duong, Jen, Campos, Alejandro D., Powis, Garth, Corr, Maripat, Karin, Michael, Raz, Eyal

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YAP–IL-6ST autoregulatory loop activated on APC loss controls colonic tumorigenesis von Taniguchi, Koji, Moroishi, Toshiro, de Jong, Petrus R., Krawczyk, Michal, Grebbin, Britta Moyo, Luo, Huiyan, Xu, Rui-hua, Golob-Schwarzl, Nicole, Schweiger, Caroline, Wang, Kepeng, Di Caro, Giuseppe, Feng, Ying, Fearon, Eric R., Raz, Eyal, Kenner, Lukas, Farin, Henner F., Guan, Kun-Liang, Haybaeck, Johannes, Datz, Christian, Zhang, Kang, Karin, Michael

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Neuronal TRPV1 activation regulates alveolar bone resorption by suppressing osteoclastogenesis via CGRP von Takahashi, Naoki, Matsuda, Yumi, Sato, Keisuke, de Jong, Petrus R., Bertin, Samuel, Tabeta, Koichi, Yamazaki, Kazuhisa

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STAT3 regulates monocyte TNF-alpha production in systemic inflammation caused by cardiac surgery with cardiopulmonary bypass von de Jong, Petrus R, Schadenberg, Alvin W L, van den Broek, Theo, Beekman, Jeffrey M, van Wijk, Femke, Coffer, Paul J, Prakken, Berent J, Jansen, Nicolaas J G

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A gp130–Src–YAP module links inflammation to epithelial regeneration von Taniguchi, Koji, Wu, Li-Wha, Grivennikov, Sergei I., de Jong, Petrus R., Lian, Ian, Yu, Fa-Xing, Wang, Kepeng, Ho, Samuel B., Boland, Brigid S., Chang, John T., Sandborn, William J., Hardiman, Gary, Raz, Eyal, Maehara, Yoshihiko, Yoshimura, Akihiko, Zucman-Rossi, Jessica, Guan, Kun-Liang, Karin, Michael

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The TRPA1 ion channel is expressed in CD4+ T cells and restrains T-cell-mediated colitis through inhibition of TRPV1 von Bertin, Samuel, Aoki-Nonaka, Yukari, Lee, Jihyung, de Jong, Petrus R, Kim, Peter, Han, Tiffany, Yu, Timothy, To, Keith, Takahashi, Naoki, Boland, Brigid S, Chang, John T, Ho, Samuel B, Herdman, Scott, Corr, Maripat, Franco, Alessandra, Sharma, Sonia, Dong, Hui, Akopian, Armen N, Raz, Eyal

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Differential homeostatic dynamics of human regulatory T-cell subsets following neonatal thymectomy von Schadenberg, Alvin W.L., MD, van den Broek, Theo, MD, Siemelink, Marten A., MD, Algra, Selma O., MD, de Jong, Petrus R., MD, Jansen, Nicolaas J.G., MD, PhD, Prakken, Berent J., MD, PhD, van Wijk, Femke, PhD

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Cyclin E1/CDK2 activation defines a key vulnerability to WEE1 kinase inhibition in gynecological cancers von Kim, Daehwan, Chung, Heekyung, Liu, Wen, Jeong, Kangjin, Ozmen, Tugba Y., Ozmen, Furkan, Rames, Matthew J., Kim, Sangyub, Guo, Xiao, Jameson, Nathan, de Jong, Petrus R., Yea, Steven, Harford, Laurie, Li, Jiali, Mathews, Cara A., Doroshow, Deborah B., Charles, Vincent J., Kim, Doris, Fischer, Kimberlee, Samatar, Ahmed A., Jubb, Adrian, Bunker, Kevin D., Blackwell, Kimberly, Simpkins, Fiona, Meric-Bernstam, Funda, Mills, Gordon B., Harismendy, Olivier, Ma, Jianhui, Lackner, Mark R.

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Definition of a Novel Feed-Forward Mechanism for Glycolysis-HIF1α Signaling in Hypoxic Tumors Highlights Aldolase A as a Therapeutic Target von Grandjean, Geoffrey, de Jong, Petrus R, James, Brian, Koh, Mei Yee, Lemos, Robert, Kingston, John, Aleshin, Alexander, Bankston, Laurie A, Miller, Claudia P, Cho, Eun Jeong, Edupuganti, Ramakrishna, Devkota, Ashwini, Stancu, Gabriel, Liddington, Robert C, Dalby, Kevin, Powis, Garth

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Absence of HIF1A Leads to Glycogen Accumulation and an Inflammatory Response That Enables Pancreatic Tumor Growth von Maruggi, Marco, Layng, Fabiana Izidro, Lemos, Jr, Robert, Garcia, Guillermina, James, Brian P, Sevilla, Monica, Soldevilla, Ferran, Baaten, Bas J, de Jong, Petrus R, Koh, Mei Yee, Powis, Garth

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STAT3: An Anti-Invasive Factor in Colorectal Cancer? von de Jong, Petrus Rudolf, Mo, Ji-Hun, Harris, Alexandra R, Lee, Jongdae, Raz, Eyal

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Ion channel TRPV1-dependent activation of PTP1B suppresses EGFR-associated intestinal tumorigenesis von de Jong, Petrus R, Takahashi, Naoki, Harris, Alexandra R, Lee, Jihyung, Bertin, Samuel, Jeffries, James, Jung, Michael, Duong, Jen, Triano, Amy I, Lee, Jongdae, Niv, Yaron, Herdman, David S, Taniguchi, Koji, Kim, Chang-Whan, Dong, Hui, Eckmann, Lars, Stanford, Stephanie M, Bottini, Nunzio, Corr, Maripat, Raz, Eyal

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MicroRNA-211 Modulates the DUSP6-ERK5 Signaling Axis to Promote BRAFV600E-Driven Melanoma Growth In Vivo and BRAF/MEK Inhibitor Resistance von Lee, Bongyong, Sahoo, Anupama, Sawada, Junko, Marchica, John, Sahoo, Sanjay, Layng, Fabiana I.A.L., Finlay, Darren, Mazar, Joseph, Joshi, Piyush, Komatsu, Masanobu, Vuori, Kristiina, de Jong, Petrus R., Ray, Animesh, Perera, Ranjan J.

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Tu1745 The TRPM8 Ion Channel Is Expressed in Colonic Mucosal Peptidergic Nerve Fibres, Which Increase During Inflammation and Associate With Dendritic Cells von Peiris, Madusha, de Jong, Petrus R, Raz, Eyal, Blackshaw, Ashley

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Hsp70 and Cardiac Surgery: Molecular Chaperone and Inflammatory Regulator with Compartmentalized Effects von de Jong, Petrus R., Schadenberg, Alvin W. L., Jansen, Nicolaas J. G., Prakken, Berent J.

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TRPV1: Turning up the heat on intestinal tumorigenesis von de Jong, Petrus R, Bertin, Samuel, Raz, Eyal

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The ion channel TRPV1 regulates the activation and proinflammatory properties of CD4+ T cells von Bertin, Samuel, Aoki-Nonaka, Yukari, de Jong, Petrus Rudolf, Nohara, Lilian L, Xu, Hongjian, Stanwood, Shawna R, Srikanth, Sonal, Lee, Jihyung, To, Keith, Abramson, Lior, Yu, Timothy, Han, Tiffany, Touma, Ranim, Li, Xiangli, González-Navajas, José M, Herdman, Scott, Corr, Maripat, Fu, Guo, Dong, Hui, Gwack, Yousang, Franco, Alessandra, Jefferies, Wilfred A, Raz, Eyal

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Mezigdomide (CC-92480), a Novel Cereblon E3 Ligase Modulator, Induces Vulnerability of Multiple Myeloma Cells to T-Cell-Mediated Killing von Gaffney, Bonny, Shi, Yu, de Jong, Petrus, Sanchez, Manuel, Fontanillo, Celia, Lopez-Girona, Antonia, Boss, Isaac W., Kurtova, Antonina, Carrancio, Soraya, Wong, Lilly, Pierce, Daniel W.

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Intrinsic Alteration of Differentiation and Glycolysis in T Lymphocytes Immediately After TCR Activation Through PSGL-1 Signaling von Hope, Jennifer L, Otero, Dennis, de Jong, Petrus, Ma, Jiadai, Henriquez, Monique, Powis, Garth, Bradley, Linda

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