Results of a randomized trial in children with Acute Myeloid Leukaemia: Medical Research Council AML12 trial von Gibson, Brenda E. S., Webb, David K. H., Howman, Andrew J., De Graaf, Siebold S. N., Harrison, Christine J., Wheatley, Keith

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Clinical relevance of Wilms tumor 1 gene mutations in childhood acute myeloid leukemia von Hollink, Iris H.I.M., van den Heuvel-Eibrink, Marry M., Zimmermann, Martin, Balgobind, Brian V., Arentsen-Peters, Susan T.C.J.M., Alders, Marielle, Willasch, Andre, Kaspers, Gertjan J.L., Trka, Jan, Baruchel, Andre, de Graaf, Siebold S.N., Creutzig, Ursula, Pieters, Rob, Reinhardt, Dirk, Zwaan, C. Michel

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Cytogenetics of Childhood Acute Myeloid Leukemia: United Kingdom Medical Research Council Treatment Trials AML 10 and 12 von HARRISON, Christine J, HILLS, Robert K, GIBSON, Brenda E. S, MOORMAN, Anthony V, GRIMWADE, David J, HANN, Ian, WEBB, David K. H, WHEATLEY, Keith, DE GRAAF, Siebold S. N, VAN DEN BERG, Eva, BURNETT, Alan K

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Low frequency of MLL -partial tandem duplications in paediatric acute myeloid leukaemia using MLPA as a novel DNA screenings technique von Balgobind, Brian V, Hollink, Iris H.I.M, Reinhardt, Dirk, van Wering, Elisabeth R, de Graaf, Siebold S.N, Baruchel, Andre, Stary, Jan, Beverloo, H. Berna, de Greef, Georgine E, Pieters, Rob, Zwaan, C. Michel, van den Heuvel-Eibrink, Marry M

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Vincristine pharmacokinetics is related to clinical outcome in children with standard risk acute lymphoblastic leukemia von Lönnerholm, Gudmar, Frost, Britt‐Marie, Abrahamsson, Jonas, Behrendtz, Mikael, Castor, Anders, Forestier, Erik, Heyman, Mats, Uges, Donald R. A., de Graaf, Siebold S. N.

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Prognostic Significance of Blasts in the Cerebrospinal Fluid Without Pleiocytosis or a Traumatic Lumbar Puncture in Children With Acute Lymphoblastic Leukemia: Experience of the Du... von TE LOO, D. Maroeska W. M, KAMPS, Willem A, VAN DER DOES-VAN DEN BERG, Anna, VAN WERING, Elisabeth R, DE GRAAF, Siebold S. N

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Cerebrospinal fluid concentrations of vincristine after bolus intravenous dosing: A surrogate marker of brain penetration von KELLIE, Stewart J, BARBARIC, Draga, KOOPMANS, Pauline, EARL, John, CARR, Deborah J, DE GRAAF, Siebold S. N

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Increasing the dosage of vincristine: A clinical and pharmacokinetic study of continuous-infusion vincristine in children with central nervous system tumors von KELLIE, Stewart J, KOOPMANS, Pauline, EARL, John, NATH, Christa, ROEBUCK, Derek, UGES, Donald R. A, DE GRAAF, Siebold S. N

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Treatment for myeloid leukaemia of Down syndrome: population‐based experience in the UK and results from the Medical Research Council AML 10 and AML 12 trials von Rao, Anupama, Hills, Robert K., Stiller, Charles, Gibson, Brenda E., Graaf, Siebold S.N., Hann, Ian M., O'Marcaigh, Aengus, Wheatley, Keith, Webb, David K.H.

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Vincristine pharmacokinetics in children with down syndrome von Lönnerholm, Gudmar, Frost, Britt-Marie, Söderhäll, Stefan, de Graaf, Siebold S.N.

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An automated method for the bioanalysis of vincristine suitable for therapeutic drug monitoring and Pharmacokinetic studies in young children von KOOPMANS, Pauline, GIDDING, Corrie E. M, DE GRAAF, Siebold S. N, UGES, Donald R. A

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Increasing the dosage of vincristine von Kellie, Stewart J., Koopmans, Pauline, Earl, John, Nath, Christa, Roebuck, Derek, Uges, Donald R. A., de Graaf, Siebold S. N.

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Synergy of Topotecan in Combination with Vincristine for Treatment of Pediatric Solid Tumor Xenografts von THOMPSON, J, GEORGE, E. O, POQUETTE, C. A, CHESHIRE, P. J, RICHMOND, L. B, DE GRAAF, S. S. N, MA, M, STEWART, C. F, HOUGHTON, P. J

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Pharmacokinetics of vincristine in children and adolescents with acute lymphocytic leukemia von Crom, William R., de Graaf, Siebold S.N., Synold, Timothy, Uges, Donald R.A., Bloemhof, Henk, Rivera, Gaston, Christensen, Michael L., Mahmoud, Hazem, Evans, William E.

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Cerebrospinal fluid concentrations of vincristine after bolus intravenous dosing von Kellie, Stewart J., Barbaric, Draga, Koopmans, Pauline, Earl, John, Carr, Deborah J., de Graaf, Siebold S. N.

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Transient cortical blindness following vincristine therapy von Schouten, Diana, de Graaf, Siebold S.N., Verrips, Aad

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Predictive value of clinical evaluation in the follow-up of children with a brain tumor von de Graaf, Nanko, Hew, Joffre M., Fock, Johanna M., Kamps, Willem A., de Graaf, Siebold S.N.

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The influence of recombinant human insulin-like growth factor-I (rhIGF-I) on cell growth and cytotoxicity of drugs in childhood rhabdomyosarcoma cell lines and xenograft models von GIDDING, C. E. M, GERMAIN, G. S, DILLING, M. B, BOER, T. G. J. M.-D, ASHMUN, R. A, DE GRAAF, S. S. N, VEVERKA, K. A, KAMPS, W. A, HOUGHTON, P. J

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Phase I clinical trial of orally administered 4-demethoxydaunorubicin (idarubicin) with pharmacokinetic and in vitro drug sensitivity testing in children with refractory leukemia von Pui, C H, de Graaf, S S, Dow, L W, Rodman, J H, Evans, W E, Alpert, B S, Murphy, S B

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Topical topics: pitfalls of "long-distance pharmacokinetics." Shipment of biologic samples to reference laboratories von Kellie, Stewart J, Uges, Donald R A, Koopmans, Pauline, Frost, Britt-Marie, De Graaf, Siebold S N

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