Cellular Imaging Predictions of Clinical Drug-Induced Liver Injury von Xu, Jinghai J., Henstock, Peter V., Dunn, Margaret C., Smith, Arthur R., Chabot, Jeffrey R., de Graaf, David

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Identification of Endoglin as a Functional Marker That Defines Long-Term Repopulating Hematopoietic Stem Cells von Chen, Chang-Zheng, Li, Min, de Graaf, David, Monti, Stefano, Göttgens, Berthold, Sanchez, Maria-Jose, Lander, Eric S., Golub, Todd R., Green, Anthony R., Lodish, Harvey F.

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A protein interaction atlas for the nuclear receptors: properties and quality of a hub-based dimerisation network von Amoutzias, Gregory D, Pichler, Elgar E, Mian, Nina, De Graaf, David, Imsiridou, Anastasia, Robinson-Rechavi, Marc, Bornberg-Bauer, Erich, Robertson, David L, Oliver, Stephen G

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A network-based approach to quantifying the impact of biologically active substances von Hoeng, Julia, Deehan, Renée, Pratt, Dexter, Martin, Florian, Sewer, Alain, Thomson, Ty M., Drubin, David A., Waters, Christina A., de Graaf, David, Peitsch, Manuel C.

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A decade of Systems Biology: where are we and where are we going to? von Peitsch, Manuel C., de Graaf, David

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Multiple effects of acetaminophen and p38 inhibitors: Towards pathway toxicology von Xu, Jinghai J., Hendriks, Bart S., Zhao, Jie, de Graaf, David

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Applying computational modeling to drug discovery and development von Kumar, Neil, Hendriks, Bart S., Janes, Kevin A., de Graaf, David, Lauffenburger, Douglas A.

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Systems diagnostics: anticipating the next generation of diagnostic tests based on mechanistic insight into disease von Fryburg, David A., Song, Diane H., Laifenfeld, Daphna, de Graaf, David

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Verification of systems biology research in the age of collaborative competition von Meyer, Pablo, Alexopoulos, Leonidas G, Bonk, Thomas, Califano, Andrea, Cho, Carolyn R, de la Fuente, Alberto, de Graaf, David, Hartemink, Alexander J, Hoeng, Julia, Ivanov, Nikolai V, Koeppl, Heinz, Linding, Rune, Marbach, Daniel, Norel, Raquel, Peitsch, Manuel C, Rice, J Jeremy, Royyuru, Ajay, Schacherer, Frank, Sprengel, Joerg, Stolle, Katrin, Vitkup, Dennis, Stolovitzky, Gustavo

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Involvement of MDR1 P‐glycoprotein in multifactorial resistance to methotrexate von Norris, Murray D., Graaf, David De, Haber, Michelle, Kavallaris, Maria, Madafiglio, Janice, Gilbert, Jayne, Kwan, Edward, Stewart, Bernard W., Mechetner, Eugene B., Gudkov, Andrei V., Roninson, Igor B.

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Blood-based identification of non-responders to anti-TNF therapy in rheumatoid arthritis von Thomson, Ty M, Lescarbeau, Reynald M, Drubin, David A, Laifenfeld, Daphna, de Graaf, David, Fryburg, David A, Littman, Bruce, Deehan, Renée, Van Hooser, Aaron

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Involvement ofMDR1 P-glycoprotein in multifactorial resistance to methotrexate von Norris, Murray D., Graaf, David De, Haber, Michelle, Kavallaris, Maria, Madafiglio, Janice, Gilbert, Jayne, Kwan, Edward, Stewart, Bernard W., Mechetner, Eugene B., Gudkov, Andrei V., Roninson, Igor B.

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568 Therapeutic Diagnostic: Identification of Molecular Mechanisms Underlying Ulcerative Colitis in Infliximab Non-Responders at Baseline von Macoritto, Michael, Thomson, Ty, Park, Jennifer S, Drubin, David, Deehan-Kenney, Renee, De Graaf, David, Laifenfeld, Daphna

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Abstract 703: Verification of a novel approach to identify disease mechanisms in breast cancer patient subsets and application of this approach to indicating and characterizing tam... von Drubin, David A., Thomson, Ty M., Park, Jennifer S., Macoritto, Michael, de Graaf, David, Kenney, Renee D.

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Elevated GM-CSF and IL-1β levels compromise the ability of p38 MAPK inhibitors to modulate TNFα levels in the human monocytic/macrophage U937 cell line von Espelin, Christopher W., Goldsipe, Arthur, Sorger, Peter K., Lauffenburger, Douglas A., de Graaf, David, Hendriks, Bart S.

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Verification of systems biology research in the age of collaborative competition: collaborative competitions in which communities of researchers compete to solve challenges may fac... von Meyer, Pablo, Alexopoulos, Leonidas G, Bonk, Thomas, Califano, Andrea, Cho, Carolyn R, de la Fuente, Alberto, de Graaf, David, Hartemink, Alexander J, Hoeng, Julia, Ivanov, Nikolai V, Koeppl, Heinz, Linding, Rune, Marbach, Daniel, Norel, Raquel, Peitsch, Manuel C, Rice, J. Jeremy, Royyuru, Ajay, Schacherer, Frank, Sprengel, Joerg, Stolle, Katrin, Vitkup, Dennis, Stolovitzky, Gustavo

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Elevated GM-CSF and IL-1β levels compromise the ability of p38 MAPK inhibitors to modulate TNFα levels in the human monocytic/macrophage U937 cell lineElectronic supplementary info... von Espelin, Christopher W, Goldsipe, Arthur, Sorger, Peter K, Lauffenburger, Douglas A, de Graaf, David, Hendriks, Bart S

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P-Glycoprotein Confers Methotrexate Resistance in 3T6 Cells with Deficient Carrier-Mediated Methotrexate Uptake von De Graaf, David, Sharma, Rakesh C., Mechetner, Eugene B., Schimke, Robert T., Roninson, Igor B.

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Elevated GM-CSF and IL-1beta levels compromise the ability of p38 MAPK inhibitors to modulate TNFalpha levels in the human monocytic/macrophage U937 cell line von Espelin, Christopher W, Goldsipe, Arthur, Sorger, Peter K, Lauffenburger, Douglas A, de Graaf, David, Hendriks, Bart S

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A protein interaction atlas for the nuclear receptors: properties and quality of a hub-based dimerisation network von Amoutzias, Grigoris, Pichler, Elgar E, Mian, Nina, De Graaf, David, Imsiridou, Anastasia, Robinson-Rechavi, Marc, Bornberg-Bauer, Erich, Robertson, David L, Oliver, Stephen G

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