Frequent incidence of BARD1-truncating mutations in germline DNA from triple-negative breast cancer patients von De Brakeleer, S., De Grève, J., Desmedt, C., Joris, S., Sotiriou, C., Piccart, M., Pauwels, I., Teugels, E.

Volltext

LBA2Investigation of non-V600 BRAF mutations commonly found in NSCLC for their sensitivity to Dabrafenib or Trametinib von Noeparast, A, Verschelden, G, Umelo, I, de Brakeleer, S, Decoste, L, Teugels, E, de Greve, J

Volltext

Investigation of non-V600 BRAF mutations commonly found in NSCLC for their sensitivity to Dabrafenib or Trametinib von Noeparast, A., Verschelden, G., Umelo, I., de Brakeleer, S., Decoste, L., Teugels, E., de Greve, J.

Volltext

Abstract PD7-04: Exome based germline mutation detection in a panel of 372 cancer associated genes in BRCA1/2-negative familial breast cancer patients von Shahi, RB, Caljon, B, De Brakeleer, S, Decoster, L, Fontaine, C, Vanacker, L, Vanhoeij, M, Pauwels, I, Bonduelle, M, Vandooren, S, Croes, D, Teugels, E, De Greve, J

Volltext

Biomarker analysis in a phase II study of sunitinib in patients with advanced melanoma von Decoster, L, Vande Broek, I, Neyns, B, Majois, F, Baurain, JF, Rottey, Sylvie, Rorive, A, Anckaert, E, De Mey, J, De Brakeleer, S, De Grève, J

Volltext

Identification of NPM1 as a potential high-penetrance gene in hereditary breast cancer von Ren, Z, Teugels, E, De Brakeleer, S, Sermijn, E, Bonduelle, M, Fontaine, C, De Greve, J

Volltext

Familial Cancer and ARLTS1 von De Brakeleer, Sylvia, Teugels, Erik, De Grève, Jacques, Frank, Bernd, Klaes, Rüdiger, Burwinkel, Barbara, Calin, George Adrian, Croce, Carlo M, Neuberg, Donna

Volltext

Loss of nuclear BRCA1 protein staining in normal tissue cells derived from BRCA1 and BRCA2 mutation carriers von De Brakeleer, S, Bogdani, M, De Greve, J, Decock, J, Sermijn, E, Bonduelle, M, Goelen, G, Teugels, E

Volltext

Non-V600 BRAF mutations recurrently found in lung cancer predict sensitivity to the combination of Trametinib and Dabrafenib von Noeparast, Amir, Teugels, Erik, Giron, Philippe, Verschelden, Gil, De Brakeleer, Sylvia, Decoster, Lore, De Grève, Jacques

Volltext

Identification of RAD17 as a candidate cancer predisposition gene in families with histories of pancreatic and breast cancers von Joris, Sofie, Giron, Philippe, Olsen, Catharina, Seneca, Sara, Gheldof, Alexander, Staessens, Shula, Shahi, Rajendra Bahadur, De Brakeleer, Sylvia, Teugels, Erik, De Grève, Jacques, Hes, Frederik J

Volltext

Identification of candidate cancer predisposing variants by performing whole-exome sequencing on index patients from BRCA1 and BRCA2-negative breast cancer families von Shahi, Rajendra Bahadur, De Brakeleer, Sylvia, Caljon, Ben, Pauwels, Ingrid, Bonduelle, Maryse, Joris, Sofie, Fontaine, Christel, Vanhoeij, Marian, Van Dooren, Sonia, Teugels, Erik, De Grève, Jacques

Volltext

The genomic landscape of nonsmall cell lung carcinoma in never smokers von Boeckx, Bram, Shahi, Rajendra B., Smeets, Dominiek, De Brakeleer, Sylvia, Decoster, Lore, Van Brussel, Thomas, Galdermans, Daniella, Vercauter, Piet, Decoster, Lynn, Alexander, Patrick, Berchem, Guy, Ocak, Sebahat, Vuylsteke, Peter, Deschepper, Koen, Lambrechts, Marc, Cappoen, Nadia, Teugels, Erik, Lambrechts, Diether, De Greve, Jacques

Volltext

Gigantic parasitic leiomyoma of 19 kg in a postmenopausal woman: A case report and review of the literature von De Brakeleer, Evy, Van Eeckhout, Eddy, Sahebali, Shaira, Cosyns, Stefan

Volltext

Gigantic parasitic leiomyoma of 19kg in a postmenopausal woman: A case report and review of the literature von De Brakeleer, Evy, Eddy Van Eeckhout, Sahebali, Shaira, Cosyns, Stefan

Volltext

Systematic Detection of Pathogenic Alu Element Insertions in NGS-Based Diagnostic Screens: The BRCA1/BRCA2 Example von De Brakeleer, Sylvia, De Grève, Jacques, Lissens, Willy, Teugels, Erik

Volltext

CRAF mutations in lung cancer can be oncogenic and predict sensitivity to combined type II RAF and MEK inhibition von Noeparast, Amir, Giron, Philippe, Noor, Alfiah, Bahadur Shahi, Rajendra, De Brakeleer, Sylvia, Eggermont, Carolien, Vandenplas, Hugo, Boeckx, Bram, Lambrechts, Diether, De Grève, Jacques, Teugels, Erik

Volltext

Type II RAF inhibitor causes superior ERK pathway suppression compared to type I RAF inhibitor in cells expressing different BRAF mutant types recurrently found in lung cancer von Noeparast, Amir, Giron, Philippe, De Brakeleer, Sylvia, Eggermont, Carolien, De Ridder, Ulrike, Teugels, Erik, De Grève, Jacques

Volltext

An alternative model for (breast) cancer predisposition von Teugels, Erik, De Brakeleer, Sylvia

Volltext

Abstract P1-10-05: Evaluation of germline whole exome sequencing of early breast cancer patients with triple negative breast cancer (TNBC) included in a prospective study of neoadj... von Fontaine, Christel, Renard, Vincent, Van den Bulck, Heidi, Vuylsteke, Peter, Glorieux, Philippe, Dopchie, Catherine, Decoster, Lore, Awada, Ahmad, Wildiers, Hans, De Brakeleer, Sylvie, Teugels, Erik, De Grève, Jacques

Volltext

Type II RAF inhibition predicts superior ERK suppression compared to type I RAF inhibition in different BRAF mutant types recurrently found in lung cancer von Giron, Philippe, Noeparast, Amir, De Brakeleer, Sylvia, De Ridder, Ulrike, Teugels, Erik, De Greve, Jacques

Volltext