SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1 von Rebsamen, Manuele, Pochini, Lorena, Stasyk, Taras, de Araújo, Mariana E. G., Galluccio, Michele, Kandasamy, Richard K., Snijder, Berend, Fauster, Astrid, Rudashevskaya, Elena L., Bruckner, Manuela, Scorzoni, Stefania, Filipek, Przemyslaw A., Huber, Kilian V. M., Bigenzahn, Johannes W., Heinz, Leonhard X., Kraft, Claudine, Bennett, Keiryn L., Indiveri, Cesare, Huber, Lukas A., Superti-Furga, Giulio

Volltext

Stability of the Endosomal Scaffold Protein LAMTOR3 Depends on Heterodimer Assembly and Proteasomal Degradation von de Araújo, Mariana E.G., Stasyk, Taras, Taub, Nicole, Ebner, Hannes L., Fürst, Beatrix, Filipek, Przemyslaw, Weys, Sabine R., Hess, Michael W., Lindner, Herbert, Kremser, Leopold, Huber, Lukas A.

Volltext

The late endosomal p14-MP1 (LAMTOR2/3) complex regulates focal adhesion dynamics during cell migration von Schiefermeier, Natalia, Scheffler, Julia M, de Araujo, Mariana E G, Stasyk, Taras, Yordanov, Teodor, Ebner, Hannes L, Offterdinger, Martin, Munck, Sebastian, Hess, Michael W, Wickström, Sara A, Lange, Anika, Wunderlich, Winfried, Fässler, Reinhard, Teis, David, Huber, Lukas A

Volltext

Lysosomal size matters von Araujo, Mariana E. G., Liebscher, Gudrun, Hess, Michael W., Huber, Lukas A.

Volltext

A substrate-specific mTORC1 pathway underlies Birt–Hogg–Dubé syndrome von Napolitano, Gennaro, Di Malta, Chiara, Esposito, Alessandra, de Araujo, Mariana E. G., Pece, Salvatore, Bertalot, Giovanni, Matarese, Maria, Benedetti, Valerio, Zampelli, Angela, Stasyk, Taras, Siciliano, Diletta, Venuta, Alessandro, Cesana, Marcella, Vilardo, Claudia, Nusco, Edoardo, Monfregola, Jlenia, Calcagnì, Alessia, Di Fiore, Pier Paolo, Huber, Lukas A., Ballabio, Andrea

Volltext

LAMTOR/Ragulator is a negative regulator of Arl8b- and BORC-dependent late endosomal positioning von Filipek, Przemyslaw A, de Araujo, Mariana E G, Vogel, Georg F, De Smet, Cedric H, Eberharter, Daniela, Rebsamen, Manuele, Rudashevskaya, Elena L, Kremser, Leopold, Yordanov, Teodor, Tschaikner, Philipp, Fürnrohr, Barbara G, Lechner, Stefan, Dunzendorfer-Matt, Theresia, Scheffzek, Klaus, Bennett, Keiryn L, Superti-Furga, Giulio, Lindner, Herbert H, Stasyk, Taras, Huber, Lukas A

Volltext

LAMTOR2-mediated modulation of NGF/MAPK activation kinetics during differentiation of PC12 cells von Thauerer, Bettina, Voegele, Paul, Hermann-Kleiter, Natascha, Thuille, Nikolaus, de Araujo, Mariana E G, Offterdinger, Martin, Baier, Gottfried, Huber, Lukas A, Baier-Bitterlich, Gabriele

Volltext

Structure of the lysosomal mTORC1–TFEB–Rag–Ragulator megacomplex von Cui, Zhicheng, Napolitano, Gennaro, de Araujo, Mariana E. G., Esposito, Alessandra, Monfregola, Jlenia, Huber, Lukas A., Ballabio, Andrea, Hurley, James H.

Volltext

Crystal structure of the human lysosomal mTORC1 scaffold complex and its impact on signaling von de Araujo, Mariana E. G., Naschberger, Andreas, Fürnrohr, Barbara G., Stasyk, Taras, Dunzendorfer-Matt, Theresia, Lechner, Stefan, Welti, Stefan, Kremser, Leopold, Shivalingaiah, Giridhar, Offterdinger, Martin, Lindner, Herbert H., Huber, Lukas A., Scheffzek, Klaus

Volltext

Establishing spatial control over TORC1 signaling von Schmidt, Oliver, de Araujo, Mariana E G

Volltext

RagD auto-activating mutations impair MiT/TFE activity in kidney tubulopathy and cardiomyopathy syndrome von Sambri, Irene, Ferniani, Marco, Campostrini, Giulia, Testa, Marialuisa, Meraviglia, Viviana, de Araujo, Mariana E. G., Dokládal, Ladislav, Vilardo, Claudia, Monfregola, Jlenia, Zampelli, Nicolina, Vecchio Blanco, Francesca Del, Torella, Annalaura, Ruosi, Carolina, Fecarotta, Simona, Parenti, Giancarlo, Staiano, Leopoldo, Bellin, Milena, Huber, Lukas A., De Virgilio, Claudio, Trepiccione, Francesco, Nigro, Vincenzo, Ballabio, Andrea

Volltext

Truncated variants of MAGEL2 are involved in the etiologies of the Schaaf-Yang and Prader-Willi syndromes von Heimdörfer, David, Vorleuter, Alexander, Eschlböck, Alexander, Spathopoulou, Angeliki, Suarez-Cubero, Marta, Farhan, Hesso, Reiterer, Veronika, Spanjaard, Melanie, Schaaf, Christian P., Huber, Lukas A., Kremser, Leopold, Sarg, Bettina, Edenhofer, Frank, Geley, Stephan, de Araujo, Mariana E.G., Huettenhofer, Alexander

Volltext

Combining high‐pressure freezing with pre‐embedding immunogold electron microscopy and tomography von Hess, Michael W., Vogel, Georg F., Yordanov, Teodor E., Witting, Barbara, Gutleben, Karin, Ebner, Hannes L., de Araujo, Mariana E. G., Filipek, Przemyslaw A., Huber, Lukas A.

Volltext

Overcoming limitations in the availability of swabs systems used for SARS-CoV-2 laboratory diagnostics von Nairz, Manfred, Bellmann-Weiler, Rosa, Ladstätter, Miriam, Schüllner, Falko, Zimmermann, Martina, Koller, Anna-Maria, Blunder, Silvia, Naschberger, Helene, Klotz, Werner, Herold, Manfred, Kerndler, Sylvia, Jeske, Martina, Haschka, David, Petzer, Verena, Schroll, Andrea, Sonnweber, Thomas, Tancevski, Ivan, Fritsche, Gernot, de Araujo, Mariana E. G., Stasyk, Taras, Huber, Lukas A., Griesmacher, Andrea, Theurl, Igor, Weiss, Günter

Volltext

Ultrastructural Morphometry Points to a New Role for LAMTOR2 in Regulating the Endo/Lysosomal System von Vogel, Georg F., Ebner, Hannes L., de Araujo, Mariana E. G., Schmiedinger, Thomas, Eiter, Oliver, Pircher, Haymo, Gutleben, Karin, Witting, Barbara, Teis, David, Huber, Lukas A., Hess, Michael W.

Volltext

Crystal Structure of the p14/MP1 Scaffolding Complex: How a Twin Couple Attaches Mitogen-Activated Protein Kinase Signaling to Late Endosomes von Kurzbauer, Robert, Teis, David, Mariana E. G. de Araujo, Maurer-Stroh, Sebastian, Eisenhaber, Frank, Bourenkov, Gleb P., Bartunik, Hans D., Hekman, Mirko, Rapp, Ulf R., Huber, Lukas A., Clausen, Tim, Huber, Robert

Volltext

The late endosomal p14-MP1 (LAMTOR2/3) complex regulates focal adhesion dynamics during cell migration von Schiefermeier, Natalia, Scheffler, Julia M, de Araujo, Mariana E.G, Stasyk, Taras, Yordanov, Teodor, Ebner, Hannes L, Offterdinger, Martin, Munck, Sebastian, Hess, Michael W, Wickström, Sara A, Lange, Anika, Wunderlich, Winfried, Fässler, Reinhard, Teis, David, Huber, Lukas A

Volltext