Epigenetic germline inheritance of diet-induced obesity and insulin resistance von Huypens, Peter, Sass, Steffen, Wu, Moya, Dyckhoff, Daniela, Tschöp, Matthias, Theis, Fabian, Marschall, Susan, de Angelis, Martin Hrabě, Beckers, Johannes

Volltext

Pathophysiology-based subphenotyping of individuals at elevated risk for type 2 diabetes von Wagner, Robert, Heni, Martin, Tabák, Adam G., Machann, Jürgen, Schick, Fritz, Randrianarisoa, Elko, Hrabě de Angelis, Martin, Birkenfeld, Andreas L., Stefan, Norbert, Peter, Andreas, Häring, Hans-Ulrich, Fritsche, Andreas

Volltext

Impaired resolution of inflammatory response in the lungs of JF1/Msf mice following carbon nanoparticle instillation von Ganguly, Koustav, Upadhyay, Swapna, Irmler, Martin, Takenaka, Shinji, Pukelsheim, Katrin, Beckers, Johannes, De Angelis, Martin Hrabé, Hamelmann, Eckard, Stoeger, Tobias, Schulz, Holger

Volltext

Identification of Serum Metabolites Associated With Risk of Type 2 Diabetes Using a Targeted Metabolomic Approach von FLOEGEL, Anna, STEFAN, Norbert, RODEN, Michael, PREHN, Cornelia, WANG-SATTLER, Rui, ILLIG, Thomas, SCHULZE, Matthias B, ADAMSKI, Jerzy, BOEING, Heiner, PISCHON, Tobias, ZHONGHAO YU, MÜHLENBRUCH, Kristin, DROGAN, Dagmar, JOOST, Hans-Georg, FRITSCHE, Andreas, HÄRING, Hans-Ulrich, HRABE DE ANGELIS, Martin, PETERS, Annette

Volltext

Acute dietary fat intake initiates alterations in energy metabolism and insulin resistance von Hernández, Elisa Álvarez, Kahl, Sabine, Seelig, Anett, Begovatz, Paul, Irmler, Martin, Kupriyanova, Yuliya, Nowotny, Bettina, Nowotny, Peter, Herder, Christian, Barosa, Cristina, Carvalho, Filipa, Rozman, Jan, Neschen, Susanne, Jones, John G, Beckers, Johannes, de Angelis, Martin Hrabě, Roden, Michael

Volltext

FMT-XCT: in vivo animal studies with hybrid fluorescence molecular tomography–X-ray computed tomography von Ale, Angelique, Ermolayev, Vladimir, Herzog, Eva, Cohrs, Christian, de Angelis, Martin Hrabé, Ntziachristos, Vasilis

Volltext

Animal models of obesity and diabetes mellitus von Kleinert, Maximilian, Clemmensen, Christoffer, Hofmann, Susanna M., Moore, Mary C., Renner, Simone, Woods, Stephen C., Huypens, Peter, Beckers, Johannes, de Angelis, Martin Hrabe, Schürmann, Annette, Bakhti, Mostafa, Klingenspor, Martin, Heiman, Mark, Cherrington, Alan D., Ristow, Michael, Lickert, Heiko, Wolf, Eckhard, Havel, Peter J., Müller, Timo D., Tschöp, Matthias H.

Volltext

Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum von Gieger, Christian, Geistlinger, Ludwig, Altmaier, Elisabeth, Hrabé de Angelis, Martin, Kronenberg, Florian, Meitinger, Thomas, Mewes, Hans-Werner, Wichmann, H-Erich, Weinberger, Klaus M, Adamski, Jerzy, Illig, Thomas, Suhre, Karsten

Volltext

Hyperexcitable interneurons trigger cortical spreading depression in an Scn1a migraine model von Auffenberg, Eva, Hedrich, Ulrike Bs, Barbieri, Raffaella, Miely, Daniela, Groschup, Bernhard, Wuttke, Thomas V, Vogel, Niklas, Lührs, Philipp, Zanardi, Ilaria, Bertelli, Sara, Spielmann, Nadine, Gailus-Durner, Valerie, Fuchs, Helmut, Hrabě de Angelis, Martin, Pusch, Michael, Dichgans, Martin, Lerche, Holger, Gavazzo, Paola, Plesnila, Nikolaus, Freilinger, Tobias

Volltext

Metabolic footprint of diabetes: a multiplatform metabolomics study in an epidemiological setting von Suhre, Karsten, Meisinger, Christa, Döring, Angela, Altmaier, Elisabeth, Belcredi, Petra, Gieger, Christian, Chang, David, Milburn, Michael V, Gall, Walter E, Weinberger, Klaus M, Mewes, Hans-Werner, Hrabé de Angelis, Martin, Wichmann, H-Erich, Kronenberg, Florian, Adamski, Jerzy, Illig, Thomas

Volltext

A patient-enriched MEIS1 coding variant causes a restless legs syndrome-like phenotype in mice von Leu, Chia-Luen, Lam, Daniel D, Salminen, Aaro V, Wefers, Benedikt, Becker, Lore, Garrett, Lillian, Rozman, Jan, Wurst, Wolfgang, Hrabě de Angelis, Martin, Hölter, Sabine M, Winkelmann, Juliane, Williams, Rhîannan H

Volltext

Post-stroke inhibition of induced NADPH oxidase type 4 prevents oxidative stress and neurodegeneration von Kleinschnitz, Christoph, Grund, Henrike, Wingler, Kirstin, Armitage, Melanie E, Jones, Emma, Mittal, Manish, Barit, David, Schwarz, Tobias, Geis, Christian, Kraft, Peter, Barthel, Konstanze, Schuhmann, Michael K, Herrmann, Alexander M, Meuth, Sven G, Stoll, Guido, Meurer, Sabine, Schrewe, Anja, Becker, Lore, Gailus-Durner, Valérie, Fuchs, Helmut, Klopstock, Thomas, de Angelis, Martin Hrabé, Jandeleit-Dahm, Karin, Shah, Ajay M, Weissmann, Norbert, Schmidt, Harald H H W

Volltext

Calcium-dependent blood-brain barrier breakdown by NOX5 limits postreperfusion benefit in stroke von Casas, Ana I, Kleikers, Pamela Wm, Geuss, Eva, Langhauser, Friederike, Adler, Thure, Busch, Dirk H, Gailus-Durner, Valerie, de Angelis, Martin Hrabê, Egea, Javier, Lopez, Manuela G, Kleinschnitz, Christoph, Schmidt, Harald Hhw

Volltext

A genome-wide perspective of genetic variation in human metabolism von Suhre, Karsten, Illig, Thomas, Gieger, Christian, Zhai, Guangju, Römisch-Margl, Werner, Wang-Sattler, Rui, Prehn, Cornelia, Altmaier, Elisabeth, Kastenmüller, Gabi, Kato, Bernet S, Mewes, Hans-Werner, Meitinger, Thomas, de Angelis, Martin Hrabé, Kronenberg, Florian, Soranzo, Nicole, Wichmann, H-Erich, Spector, Tim D, Adamski, Jerzy

Volltext

Rapamycin extends murine lifespan but has limited effects on aging von Neff, Frauke, Flores-Dominguez, Diana, Ryan, Devon P, Horsch, Marion, Schröder, Susanne, Adler, Thure, Afonso, Luciana Caminha, Aguilar-Pimentel, Juan Antonio, Becker, Lore, Garrett, Lillian, Hans, Wolfgang, Hettich, Moritz M, Holtmeier, Richard, Hölter, Sabine M, Moreth, Kristin, Prehn, Cornelia, Puk, Oliver, Rácz, Ildikó, Rathkolb, Birgit, Rozman, Jan, Naton, Beatrix, Ordemann, Rainer, Adamski, Jerzy, Beckers, Johannes, Bekeredjian, Raffi, Busch, Dirk H, Ehninger, Gerhard, Graw, Jochen, Höfler, Heinz, Klingenspor, Martin, Klopstock, Thomas, Ollert, Markus, Stypmann, Jörg, Wolf, Eckhard, Wurst, Wolfgang, Zimmer, Andreas, Fuchs, Helmut, Gailus-Durner, Valérie, Hrabe de Angelis, Martin, Ehninger, Dan

Volltext

Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium von Meehan, Terrence F, Conte, Nathalie, West, David B, Jacobsen, Julius O, Mason, Jeremy, Warren, Jonathan, Chen, Chao-Kung, Tudose, Ilinca, Relac, Mike, Matthews, Peter, Karp, Natasha, Santos, Luis, Fiegel, Tanja, Ring, Natalie, Westerberg, Henrik, Greenaway, Simon, Sneddon, Duncan, Morgan, Hugh, Codner, Gemma F, Stewart, Michelle E, Brown, James, Horner, Neil, Haendel, Melissa, Washington, Nicole, Mungall, Christopher J, Reynolds, Corey L, Gallegos, Juan, Gailus-Durner, Valerie, Sorg, Tania, Pavlovic, Guillaume, Bower, Lynette R, Moore, Mark, Morse, Iva, Gao, Xiang, Tocchini-Valentini, Glauco P, Obata, Yuichi, Cho, Soo Young, Seong, Je Kyung, Seavitt, John, Beaudet, Arthur L, Dickinson, Mary E, Herault, Yann, Wurst, Wolfgang, de Angelis, Martin Hrabe, Lloyd, K C Kent, Flenniken, Ann M, Nutter, Lauryl M J, Newbigging, Susan, McKerlie, Colin, Justice, Monica J, Murray, Stephen A, Svenson, Karen L, Braun, Robert E, White, Jacqueline K, Bradley, Allan, Flicek, Paul, Wells, Sara, Skarnes, William C, Adams, David J, Parkinson, Helen, Mallon, Ann-Marie, Brown, Steve D M, Smedley, Damian

Volltext

High-throughput discovery of novel developmental phenotypes von Dickinson, Mary E., Flenniken, Ann M., Ji, Xiao, Teboul, Lydia, Wong, Michael D., White, Jacqueline K., Meehan, Terrence F., Weninger, Wolfgang J., Westerberg, Henrik, Adissu, Hibret, Baker, Candice N., Bower, Lynette, Brown, James M., Caddle, L. Brianna, Chiani, Francesco, Clary, Dave, Cleak, James, Daly, Mark J., Denegre, James M., Doe, Brendan, Dolan, Mary E., Edie, Sarah M., Fuchs, Helmut, Gailus-Durner, Valerie, Galli, Antonella, Gambadoro, Alessia, Gallegos, Juan, Guo, Shiying, Horner, Neil R., Hsu, Chih-Wei, Johnson, Sara J., Kalaga, Sowmya, Keith, Lance C., Lanoue, Louise, Lawson, Thomas N., Lek, Monkol, Mark, Manuel, Marschall, Susan, Mason, Jeremy, McElwee, Melissa L., Newbigging, Susan, Nutter, Lauryl M. J., Peterson, Kevin A., Ramirez-Solis, Ramiro, Rowland, Douglas J., Ryder, Edward, Samocha, Kaitlin E., Seavitt, John R., Selloum, Mohammed, Szoke-Kovacs, Zsombor, Tamura, Masaru, Trainor, Amanda G., Tudose, Ilinca, Wakana, Shigeharu, Warren, Jonathan, Wendling, Olivia, West, David B., Wong, Leeyean, Yoshiki, Atsushi, Wurst, Wolfgang, MacArthur, Daniel G., Tocchini-Valentini, Glauco P., Gao, Xiang, Flicek, Paul, Bradley, Allan, Skarnes, William C., Justice, Monica J., Parkinson, Helen E., Moore, Mark, Wells, Sara, Braun, Robert E., Svenson, Karen L., de Angelis, Martin Hrabe, Herault, Yann, Mohun, Tim, Mallon, Ann-Marie, Henkelman, R. Mark, Brown, Steve D. M., Adams, David J., Lloyd, K. C. Kent, McKerlie, Colin, Beaudet, Arthur L., Bućan, Maja, Murray, Stephen A.

Volltext

TRPS1 maintains luminal progenitors in the mammary gland by repressing SRF/MRTF activity von Tollot-Wegner, Marie, Jessen, Marco, Kim, KyungMok, Sanz-Moreno, Adrián, Spielmann, Nadine, Gailus-Durner, Valerie, Fuchs, Helmut, Hrabe de Angelis, Martin, von Eyss, Björn

Volltext

Ribosomal mutations cause p53-mediated dark skin and pleiotropic effects von Li, Jun Z, Sabnis, Amit J, Tabor, Holly K, Barsh, Gregory S, McGowan, Kelly A, Fuchs, Helmut, Zhang, Weibin, Myers, Richard M, Park, Christopher Y, de Angelis, Martin Hrabé, Attardi, Laura D, Beaudry, Veronica

Volltext

Circulating Lysophosphatidylcholines Are Markers of a Metabolically Benign Nonalcoholic Fatty Liver von LEHMANN, Rainer, FRANKEN, Holger, KÖNIGSRAINER, Alfred, MACHANN, Jürgen, SCHICK, Fritz, DE ANGELIS, Martin Hrabé, SCHWAB, Matthias, STAIGER, Harald, SCHLEICHER, Erwin, GASTALDELLI, Amalia, FRITSCHE, Andreas, HÄRING, Hans-Ulrich, DAMMEIER, Sascha, STEFAN, Norbert, ROSENBAUM, Lars, KANTARTZIS, Konstantinos, PETER, Andreas, ZELL, Andreas, ADAM, Patrick, JIA LI, GUOWANG XU

Volltext