Synthesis, Pharmacological Profile and Docking Studies of New Sulfonamides Designed as Phosphodiesterase-4 Inhibitors von Nunes, Isabelle Karine da Costa, de Souza, Everton Tenório, Cardozo, Suzana Vanessa S, Carvalho, Vinicius de Frias, Romeiro, Nelilma Correia, Silva, Patrícia Machado Rodrigues E, Martins, Marco Aurélio, Barreiro, Eliezer J, Lima, Lídia Moreira

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Zebrafish (Danio rerio) water tank model for the investigation of drug metabolism: Progress, outlook, and challenges von Sardela, Vinicius Figueiredo, Anselmo, Carina de Souza, Nunes, Isabelle Karine da Costa, Carneiro, Gabriel Reis Alves, Santos, Gustavo Ramalho Cardoso, Carvalho, Aline Reis, Labanca, Bruna de Jesus, Silva Oliveira, Daniely, Ribeiro, William Dias, Araujo, Amanda Lessa Dutra, Padilha, Monica Costa, Lima, Cleverton Kleiton Freitas, Sousa, Valeria Pereira, Aquino Neto, Francisco Radler, Gualberto Pereira, Henrique Marcelo

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Synthesis, solubility, plasma stability, and pharmacological evaluation of novel sulfonylhydrazones designed as anti-diabetic agents von Zapata-Sudo, Gisele, da Costa Nunes, Isabelle Karine, Araujo, Josenildo Segundo Chaves, da Silva, Jaqueline Soares, Trachez, Margarete Manhães, da Silva, Tiago Fernandes, da Costa, Filipe P, Sudo, Roberto Takashi, Barreiro, Eliezer J, Lima, Lídia Moreira

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New phosphodiesterase-4 inhibitors present airways relaxant activity in a guinea pig acute asthma model von Martins, Italo Rossi Roseno, de Melo Medeiros, Millena, Vasconcelos, Luiz Henrique César, Silva, Maria da Conceição Correia, Queiroga, Fernando Ramos, Cavalcante-Silva, Luiz Henrique Agra, da Costa Nunes, Isabelle Karine, Lima, Lidia Moreira, da Silva, Patricia Mirella, Silva, Bagnólia Araújo da

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Discovery of sulfonyl hydrazone derivative as a new selective PDE4A and PDE4D inhibitor by lead-optimization approach on the prototype LASSBio-448: In vitro and in vivo preclinical... von Nunes, Isabelle Karine da Costa, de Souza, Everton Tenório, Martins, Italo Rossi Roseno, Barbosa, Gisele, Moraes Junior, Manoel Oliveira de, Medeiros, Millena de Melo, Silva, Sheyla Welma Duarte, Balliano, Tatiane Luciano, da Silva, Bagnólia Araújo, Silva, Patrícia Machado Rodrigues, Carvalho, Vinicius de Frias, Martins, Marco Aurélio, Lima, Lidia Moreira

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Is zebrafish (Danio rerio) water tank model applicable for the assessment of glucocorticoids metabolism? The budesonide assessment von de Araujo, Amanda Lessa Dutra, Nunes, Isabelle Karine da Costa, Sardela, Vinicius Figueiredo, Pereira, Henrique Marcelo Gualberto, Cabral, Lucio Mendes, Anselmo, Carina de Souza

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A simple quinoline salt derivative is active in vitro against Plasmodiumf alciparum asexual blood stages and inhibits the development of cerebral malaria in murine model von Bezerra Bellei, Jessica Correa, Glanzmann, Nícolas, Carpinter, Bárbara Albuquerque, Renhe, Daniela Chaves, Marques, Carolina Brandi, Azevedo, Marina Rocha, Barreto, Livia Maria, Rocha, Vinicius Novaes, Karine da Costa Nunes, Isabelle, Gualberto Pereira, Henrique Marcelo, Coimbra, Elaine Soares, Ferraz Coelho, Eduardo Antônio, David da Silva, Adilson, de Pilla Varotti, Fernando, Gorza Scopel, Kézia Katiani

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Extracellular Vesicles From Stored Red Blood Cells Convey Heme and Induce Spic Expression on Human Monocytes von Amorim, Carolinne Souza, Moraes, João Alfredo, Magdalena, Ingrid de Jesus, López, Sheila Gutiérrez, Carneiro, Ana Carolina Dudenhoeffer, Nunes, Isabelle Karine da Costa, Pizzatti, Luciana, Sardela, Vinícius Figueiredo, Aquino Neto, Francisco Radler, Mirotti, Luciana Cristina, Pereira, Henrique Marcelo Gualberto, Renovato-Martins, Mariana

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Metabolism of synthetic cathinones through the zebrafish water tank model: a promising tool for forensic toxicology laboratories von Prado, Estefany, Matos, Rebecca Rodrigues, de Lima Gomes, Geovana Maria, de Sá, Clarisse Baptista Lima, da Costa Nunes, Isabelle Karine, de Souza Anselmo, Carina, de Oliveira, Adriana Sousa, do Amaral Cohen, Luciana Silva, de Siqueira, Denilson Soares, de Oliveira, Marco Antônio Martins, Ambrosio, João Carlos Laboissiere, Costa, Gabriela Vanini, de Aquino Neto, Francisco Radler, Padilha, Monica Costa, Pereira, Henrique Marcelo Gualberto

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The Importance of Metabolism Study in the Early Stages of Drugs Development von Nunes, Isabelle Karine da Costa

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Benzenesulfonamide attenuates monocrotaline-induced pulmonary arterial hypertension in a rat model von Zapata-Sudo, Gisele, Pontes, Luana Braga, Silva, Jaqueline Soares da, Lima, Lídia Moreira, Nunes, Isabelle Karine da Costa, Barreiro, Eliezer Jesus, Sudo, Roberto Takashi

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Synthesis and biological activity of novel 4-aminoquinoline/1,2,3-triazole hybrids against Leishmania amazonensis von Glanzmann, Nícolas, Antinarelli, Luciana Maria Ribeiro, da Costa Nunes, Isabelle Karine, Pereira, Henrique Marcelo Gualberto, Coelho, Eduardo Antonio Ferraz, Coimbra, Elaine Soares, da Silva, Adilson David

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Development of a liquid chromatography Q Exactive high resolution mass spectrometry method by the Box-Behnken design for the investigation of sibutramine urinary metabolites von de Souza Anselmo, Carina, Matias, Bernardo Fonseca, Sardela, Vinicius Figueiredo, Ribeiro, Ana Ferreira, da Costa Nunes, Isabelle Karine, de Sousa, Valéria Pereira, Pereira, Henrique Marcelo Gualberto

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A simple quinoline salt derivative is active in vitro against Plasmodiumfalciparum asexual blood stages and inhibits the development of cerebral malaria in murine model von Bezerra Bellei, Jessica Correa, Glanzmann, Nícolas, Carpinter, Bárbara Albuquerque, Renhe, Daniela Chaves, Marques, Carolina Brandi, Azevedo, Marina Rocha, Barreto, Livia Maria, Rocha, Vinicius Novaes, Karine da Costa Nunes, Isabelle, Gualberto Pereira, Henrique Marcelo, Coimbra, Elaine Soares, Ferraz Coelho, Eduardo Antônio, David da Silva, Adilson, de Pilla Varotti, Fernando, Gorza Scopel, Kézia Katiani

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