Strand-Specific miR-28-5p and miR-28-3p Have Distinct Effects in Colorectal Cancer Cells von Almeida, Maria I, Nicoloso, Milena S, Zeng, Lizhi, Ivan, Cristina, Spizzo, Riccardo, Gafà, Roberta, Xiao, Lianchun, Zhang, Xinna, Vannini, Ivan, Fanini, Francesca, Fabbri, Muller, Lanza, Giovanni, Reis, Rui M, Zweidler–McKay, Patrick A, Calin, George A

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Mixed‐phenotype acute leukemia: A cohort and consensus research strategy from the Children’s Oncology Group Acute Leukemia of Ambiguous Lineage Task Force von Orgel, Etan, Alexander, Thomas B., Wood, Brent L., Kahwash, Samir B., Devidas, Meenakshi, Dai, Yunfeng, Alonzo, Todd A., Mullighan, Charles G., Inaba, Hiroto, Hunger, Stephen P., Raetz, Elizabeth A., Gamis, Alan S., Rabin, Karen R., Carroll, Andrew J., Heerema, Nyla A., Berman, Jason N., Woods, William G., Loh, Mignon L., Zweidler‐McKay, Patrick A., Horan, John T.

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MLL-Rearranged Acute Lymphoblastic Leukemias Activate BCL-2 through H3K79 Methylation and Are Sensitive to the BCL-2-Specific Antagonist ABT-199 von Benito, Juliana M., Godfrey, Laura, Kojima, Kensuke, Hogdal, Leah, Wunderlich, Mark, Geng, Huimin, Marzo, Isabel, Harutyunyan, Karine G., Golfman, Leonard, North, Phillip, Kerry, Jon, Ballabio, Erica, Chonghaile, Triona Ní, Gonzalo, Oscar, Qiu, Yihua, Jeremias, Irmela, Debose, LaKiesha, O’Brien, Eric, Ma, Helen, Zhou, Ping, Jacamo, Rodrigo, Park, Eugene, Coombes, Kevin R., Zhang, Nianxiang, Thomas, Deborah A., O’Brien, Susan, Kantarjian, Hagop M., Leverson, Joel D., Kornblau, Steven M., Andreeff, Michael, Müschen, Markus, Zweidler-McKay, Patrick A., Mulloy, James C., Letai, Anthony, Milne, Thomas A., Konopleva, Marina

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Pronounced hypoxia in models of murine and human leukemia: high efficacy of hypoxia-activated prodrug PR-104 von Benito, Juliana, Shi, Yuexi, Szymanska, Barbara, Carol, Hernan, Boehm, Ingrid, Lu, Hongbo, Konoplev, Sergej, Fang, Wendy, Zweidler-McKay, Patrick A, Campana, Dario, Borthakur, Gautam, Bueso-Ramos, Carlos, Shpall, Elizabeth, Thomas, Deborah A, Jordan, Craig T, Kantarjian, Hagop, Wilson, William R, Lock, Richard, Andreeff, Michael, Konopleva, Marina

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Epigenetic inactivation of Notch-Hes pathway in human B-cell acute lymphoblastic leukemia von Kuang, Shao-Qing, Fang, Zhihong, Zweidler-McKay, Patrick A, Yang, Hui, Wei, Yue, Gonzalez-Cervantes, Emilio A, Boumber, Yanis, Garcia-Manero, Guillermo

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Integrative genomic characterization of oral squamous cell carcinoma identifies frequent somatic drivers von Pickering, Curtis R, Zhang, Jiexin, Yoo, Suk Young, Bengtsson, Linnea, Moorthy, Shhyam, Neskey, David M, Zhao, Mei, Ortega Alves, Marcus V, Chang, Kyle, Drummond, Jennifer, Cortez, Elsa, Xie, Tong-Xin, Zhang, Di, Chung, Woonbok, Issa, Jean-Pierre J, Zweidler-McKay, Patrick A, Wu, Xifeng, El-Naggar, Adel K, Weinstein, John N, Wang, Jing, Muzny, Donna M, Gibbs, Richard A, Wheeler, David A, Myers, Jeffrey N, Frederick, Mitchell J

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CD123 expression patterns and selective targeting with a CD123-targeted antibody-drug conjugate (IMGN632) in acute lymphoblastic leukemia von Angelova, Evgeniya, Audette, Charlene, Kovtun, Yelena, Daver, Naval, Wang, Sa A, Pierce, Sherry, Konoplev, Sergej N, Khogeer, Haitham, Jorgensen, Jeffrey L, Konopleva, Marina, Zweidler-McKay, Patrick A, Medeiros, L Jeffrey, Kantarjian, Hagop M, Jabbour, Elias J, Khoury, Joseph D

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Enforced fucosylation of cord blood hematopoietic cells accelerates neutrophil and platelet engraftment after transplantation von Popat, Uday, Mehta, Rohtesh S., Rezvani, Katayoun, Fox, Patricia, Kondo, Kayo, Marin, David, McNiece, Ian, Oran, Betul, Hosing, Chitra, Olson, Amanda, Parmar, Simrit, Shah, Nina, Andreeff, Michael, Kebriaei, Partow, Kaur, Indreshpal, Yvon, Eric, de Lima, Marcos, Cooper, Laurence J.N., Tewari, Priti, Champlin, Richard E., Nieto, Yago, Andersson, Borje S., Alousi, Amin, Jones, Roy B., Qazilbash, Muzaffar H., Bashir, Qaiser, Ciurea, Stefan, Ahmed, Sairah, Anderlini, Paolo, Bosque, Doyle, Bollard, Catherine, Molldrem, Jeffrey J., Chen, Julianne, Rondon, Gabriela, Thomas, Michael, Miller, Leonard, Wolpe, Steve, Simmons, Paul, Robinson, Simon, Zweidler-McKay, Patrick A., Shpall, Elizabeth J.

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Notch activation inhibits AML growth and survival: a potential therapeutic approach von Kannan, Sankaranarayanan, Sutphin, Robert M, Hall, Mandy G, Golfman, Leonard S, Fang, Wendy, Nolo, Riitta M, Akers, Lauren J, Hammitt, Richard A, McMurray, John S, Kornblau, Steven M, Melnick, Ari M, Figueroa, Maria E, Zweidler-McKay, Patrick A

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Prognostic impact of minimal residual disease at the end of consolidation in NCI standard‐risk B‐lymphoblastic leukemia: A report from the Children's Oncology Group von Rau, Rachel E., Dai, Yunfeng, Devidas, Meenakshi, Rabin, Karen R., Zweidler‐McKay, Patrick, Angiolillo, Anne, Schore, Reuven J., Burke, Michael J., Salzer, Wanda L., Heerema, Nyla A., Carroll, Andrew J., Winick, Naomi J., Hunger, Stephen P., Raetz, Elizabeth A., Loh, Mignon L., Wood, Brent L., Borowitz, Michael J.

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Critical Role of Notch Signaling in Osteosarcoma Invasion and Metastasis von Zhang, Pingyu, Yang, Yanwen, Zweidler-McKay, Patrick A, Hughes, Dennis P M

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Absolute Lymphocyte Count Is a Novel Prognostic Indicator in ALL and AML : Implications for Risk Stratification and Future Studies von DE ANGULO, Guillermo, YUEN, Carrie, PALLA, Shana L, ANDERSON, Peter M, ZWEIDLER-MCKAY, Patrick A

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The selective Trk inhibitor AZ623 inhibits brain‐derived neurotrophic factor–mediated neuroblastoma cell proliferation and signaling and is synergistic with topotecan von Zage, Peter E., Graham, Timothy C., Zeng, Lizhi, Fang, Wendy, Pien, Christine, Thress, Ken, Omer, Charles, Brown, Jeffrey L., Zweidler ‐McKay, Patrick A.

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Replacing cyclophosphamide/cytarabine/mercaptopurine with cyclophosphamide/etoposide during consolidation/delayed intensification does not improve outcome for pediatric B-cell acut... von Burke, Michael J, Salzer, Wanda L, Devidas, Meenakshi, Dai, Yunfeng, Gore, Lia, Hilden, Joanne M, Larsen, Eric, Rabin, Karen R, Zweidler-McKay, Patrick A, Borowitz, Michael J, Wood, Brent, Heerema, Nyla A, Carroll, Andrew J, Winick, Naomi, Carroll, William L, Raetz, Elizabeth A, Loh, Mignon L, Hunger, Stephen P

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Children's Oncology Group AALL0434: A Phase III Randomized Clinical Trial Testing Nelarabine in Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia von Dunsmore, Kimberly P., Winter, Stuart S., Devidas, Meenakshi, Wood, Brent L., Esiashvili, Natia, Chen, Zhiguo, Eisenberg, Nancy, Briegel, Nikki, Hayashi, Robert J., Gastier-Foster, Julie M., Carroll, Andrew J., Heerema, Nyla A., Asselin, Barbara L., Rabin, Karen R., Zweidler-Mckay, Patrick A., Raetz, Elizabeth A., Loh, Mignon L., Schultz, Kirk R., Winick, Naomi J., Carroll, William L., Hunger, Stephen P.

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Notch pathway activation induces neuroblastoma tumor cell growth arrest von Zage, Peter E., Nolo, Riitta, Fang, Wendy, Stewart, John, Garcia-Manero, Guillermo, Zweidler-McKay, Patrick A.

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BCL6 Antagonizes NOTCH2 to Maintain Survival of Human Follicular Lymphoma Cells von Valls, Ester, Lobry, Camille, Geng, Huimin, Wang, Ling, Cardenas, Mariano, Rivas, Martín, Cerchietti, Leandro, Oh, Philmo, Yang, Shao Ning, Oswald, Erin, Graham, Camille W, Jiang, Yanwen, Hatzi, Katerina, Agirre, Xabier, Perkey, Eric, Li, Zhuoning, Tam, Wayne, Bhatt, Kamala, Leonard, John P, Zweidler-McKay, Patrick A, Maillard, Ivan, Elemento, Olivier, Ci, Weimin, Aifantis, Iannis, Melnick, Ari

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PB1888: TRIAL IN PROGRESS: PHASE 1B/2 STUDY OF PIVEKIMAB SUNIRINE (PVEK, IMGN632) IN COMBINATION WITH VENETOCLAX/AZACITIDINE OR MAGROLIMAB FOR PATIENTS WITH CD123‐POSITIVE ACUTE MY... von Daver, Naval, Montesinos, Pau, Aribi, Ahmed, Martinelli, Giovanni, Wang, Eunice, Altman, Jessica, Roboz, Gail, Burke, Patrick, Walter, Roland, Benga, Kebede, Sloss, Callum, Malcolm, Kara, Zweidler‐Mckay, Patrick, Sweet, Kendra

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CARMA1 controls Th2 cell-specific cytokine expression through regulating JunB and GATA3 transcription factors von Blonska, Marzenna, Joo, Donghyun, Zweidler-McKay, Patrick A, Zhao, Qingyu, Lin, Xin

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Improved Survival for Children and Young Adults With T-Lineage Acute Lymphoblastic Leukemia: Results From the Children's Oncology Group AALL0434 Methotrexate Randomization von Winter, Stuart S, Dunsmore, Kimberly P, Devidas, Meenakshi, Wood, Brent L, Esiashvili, Natia, Chen, Zhiguo, Eisenberg, Nancy, Briegel, Nikki, Hayashi, Robert J, Gastier-Foster, Julie M, Carroll, Andrew J, Heerema, Nyla A, Asselin, Barbara L, Gaynon, Paul S, Borowitz, Michael J, Loh, Mignon L, Rabin, Karen R, Raetz, Elizabeth A, Zweidler-Mckay, Patrick A, Winick, Naomi J, Carroll, William L, Hunger, Stephen P

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