Strand-Specific miR-28-5p and miR-28-3p Have Distinct Effects in Colorectal Cancer Cells von Almeida, Maria I, Nicoloso, Milena S, Zeng, Lizhi, Ivan, Cristina, Spizzo, Riccardo, Gafà, Roberta, Xiao, Lianchun, Zhang, Xinna, Vannini, Ivan, Fanini, Francesca, Fabbri, Muller, Lanza, Giovanni, Reis, Rui M, Zweidler–McKay, Patrick A, Calin, George A

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Mixed‐phenotype acute leukemia: A cohort and consensus research strategy from the Children’s Oncology Group Acute Leukemia of Ambiguous Lineage Task Force von Orgel, Etan, Alexander, Thomas B., Wood, Brent L., Kahwash, Samir B., Devidas, Meenakshi, Dai, Yunfeng, Alonzo, Todd A., Mullighan, Charles G., Inaba, Hiroto, Hunger, Stephen P., Raetz, Elizabeth A., Gamis, Alan S., Rabin, Karen R., Carroll, Andrew J., Heerema, Nyla A., Berman, Jason N., Woods, William G., Loh, Mignon L., Zweidler‐McKay, Patrick A., Horan, John T.

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MLL-Rearranged Acute Lymphoblastic Leukemias Activate BCL-2 through H3K79 Methylation and Are Sensitive to the BCL-2-Specific Antagonist ABT-199 von Benito, Juliana M., Godfrey, Laura, Kojima, Kensuke, Hogdal, Leah, Wunderlich, Mark, Geng, Huimin, Marzo, Isabel, Harutyunyan, Karine G., Golfman, Leonard, North, Phillip, Kerry, Jon, Ballabio, Erica, Chonghaile, Triona Ní, Gonzalo, Oscar, Qiu, Yihua, Jeremias, Irmela, Debose, LaKiesha, O’Brien, Eric, Ma, Helen, Zhou, Ping, Jacamo, Rodrigo, Park, Eugene, Coombes, Kevin R., Zhang, Nianxiang, Thomas, Deborah A., O’Brien, Susan, Kantarjian, Hagop M., Leverson, Joel D., Kornblau, Steven M., Andreeff, Michael, Müschen, Markus, Zweidler-McKay, Patrick A., Mulloy, James C., Letai, Anthony, Milne, Thomas A., Konopleva, Marina

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Integrative genomic characterization of oral squamous cell carcinoma identifies frequent somatic drivers von Pickering, Curtis R, Zhang, Jiexin, Yoo, Suk Young, Bengtsson, Linnea, Moorthy, Shhyam, Neskey, David M, Zhao, Mei, Ortega Alves, Marcus V, Chang, Kyle, Drummond, Jennifer, Cortez, Elsa, Xie, Tong-Xin, Zhang, Di, Chung, Woonbok, Issa, Jean-Pierre J, Zweidler-McKay, Patrick A, Wu, Xifeng, El-Naggar, Adel K, Weinstein, John N, Wang, Jing, Muzny, Donna M, Gibbs, Richard A, Wheeler, David A, Myers, Jeffrey N, Frederick, Mitchell J

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Pronounced hypoxia in models of murine and human leukemia: high efficacy of hypoxia-activated prodrug PR-104 von Benito, Juliana, Shi, Yuexi, Szymanska, Barbara, Carol, Hernan, Boehm, Ingrid, Lu, Hongbo, Konoplev, Sergej, Fang, Wendy, Zweidler-McKay, Patrick A, Campana, Dario, Borthakur, Gautam, Bueso-Ramos, Carlos, Shpall, Elizabeth, Thomas, Deborah A, Jordan, Craig T, Kantarjian, Hagop, Wilson, William R, Lock, Richard, Andreeff, Michael, Konopleva, Marina

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CD123 expression patterns and selective targeting with a CD123-targeted antibody-drug conjugate (IMGN632) in acute lymphoblastic leukemia von Angelova, Evgeniya, Audette, Charlene, Kovtun, Yelena, Daver, Naval, Wang, Sa A, Pierce, Sherry, Konoplev, Sergej N, Khogeer, Haitham, Jorgensen, Jeffrey L, Konopleva, Marina, Zweidler-McKay, Patrick A, Medeiros, L Jeffrey, Kantarjian, Hagop M, Jabbour, Elias J, Khoury, Joseph D

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Enforced fucosylation of cord blood hematopoietic cells accelerates neutrophil and platelet engraftment after transplantation von Popat, Uday, Mehta, Rohtesh S., Rezvani, Katayoun, Fox, Patricia, Kondo, Kayo, Marin, David, McNiece, Ian, Oran, Betul, Hosing, Chitra, Olson, Amanda, Parmar, Simrit, Shah, Nina, Andreeff, Michael, Kebriaei, Partow, Kaur, Indreshpal, Yvon, Eric, de Lima, Marcos, Cooper, Laurence J.N., Tewari, Priti, Champlin, Richard E., Nieto, Yago, Andersson, Borje S., Alousi, Amin, Jones, Roy B., Qazilbash, Muzaffar H., Bashir, Qaiser, Ciurea, Stefan, Ahmed, Sairah, Anderlini, Paolo, Bosque, Doyle, Bollard, Catherine, Molldrem, Jeffrey J., Chen, Julianne, Rondon, Gabriela, Thomas, Michael, Miller, Leonard, Wolpe, Steve, Simmons, Paul, Robinson, Simon, Zweidler-McKay, Patrick A., Shpall, Elizabeth J.

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Epigenetic inactivation of Notch-Hes pathway in human B-cell acute lymphoblastic leukemia von Kuang, Shao-Qing, Fang, Zhihong, Zweidler-McKay, Patrick A, Yang, Hui, Wei, Yue, Gonzalez-Cervantes, Emilio A, Boumber, Yanis, Garcia-Manero, Guillermo

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Notch activation inhibits AML growth and survival: a potential therapeutic approach von Kannan, Sankaranarayanan, Sutphin, Robert M, Hall, Mandy G, Golfman, Leonard S, Fang, Wendy, Nolo, Riitta M, Akers, Lauren J, Hammitt, Richard A, McMurray, John S, Kornblau, Steven M, Melnick, Ari M, Figueroa, Maria E, Zweidler-McKay, Patrick A

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Regulation of NOTCH signaling by reciprocal inhibition of HES1 and Deltex 1 and its role in osteosarcoma invasiveness von Zhang, P, Yang, Y, Nolo, R, Zweidler-McKay, P A, Hughes, D P M

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Critical Role of Notch Signaling in Osteosarcoma Invasion and Metastasis von Zhang, Pingyu, Yang, Yanwen, Zweidler-McKay, Patrick A, Hughes, Dennis P M

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Replacing cyclophosphamide/cytarabine/mercaptopurine with cyclophosphamide/etoposide during consolidation/delayed intensification does not improve outcome for pediatric B-cell acut... von Burke, Michael J, Salzer, Wanda L, Devidas, Meenakshi, Dai, Yunfeng, Gore, Lia, Hilden, Joanne M, Larsen, Eric, Rabin, Karen R, Zweidler-McKay, Patrick A, Borowitz, Michael J, Wood, Brent, Heerema, Nyla A, Carroll, Andrew J, Winick, Naomi, Carroll, William L, Raetz, Elizabeth A, Loh, Mignon L, Hunger, Stephen P

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Notch signaling is a potent inducer of growth arrest and apoptosis in a wide range of B-cell malignancies von Zweidler-McKay, Patrick A., He, Yiping, Xu, Lanwei, Rodriguez, Carlos G., Karnell, Fredrick G., Carpenter, Andrea C., Aster, Jon C., Allman, David, Pear, Warren S.

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The selective Trk inhibitor AZ623 inhibits brain‐derived neurotrophic factor–mediated neuroblastoma cell proliferation and signaling and is synergistic with topotecan von Zage, Peter E., Graham, Timothy C., Zeng, Lizhi, Fang, Wendy, Pien, Christine, Thress, Ken, Omer, Charles, Brown, Jeffrey L., Zweidler ‐McKay, Patrick A.

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BCL6 Antagonizes NOTCH2 to Maintain Survival of Human Follicular Lymphoma Cells von Valls, Ester, Lobry, Camille, Geng, Huimin, Wang, Ling, Cardenas, Mariano, Rivas, Martín, Cerchietti, Leandro, Oh, Philmo, Yang, Shao Ning, Oswald, Erin, Graham, Camille W, Jiang, Yanwen, Hatzi, Katerina, Agirre, Xabier, Perkey, Eric, Li, Zhuoning, Tam, Wayne, Bhatt, Kamala, Leonard, John P, Zweidler-McKay, Patrick A, Maillard, Ivan, Elemento, Olivier, Ci, Weimin, Aifantis, Iannis, Melnick, Ari

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CARMA1 controls Th2 cell-specific cytokine expression through regulating JunB and GATA3 transcription factors von Blonska, Marzenna, Joo, Donghyun, Zweidler-McKay, Patrick A, Zhao, Qingyu, Lin, Xin

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Notch/HES1-mediated PARP1 activation: a cell type–specific mechanism for tumor suppression von Kannan, Sankaranarayanan, Fang, Wendy, Song, Guangchun, Mullighan, Charles G., Hammitt, Richard, McMurray, John, Zweidler-McKay, Patrick A.

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Targeting the NRF2/HO-1 Antioxidant Pathway in FLT3-ITD-Positive AML Enhances Therapy Efficacy von Kannan, Sankaranarayan, Irwin, Mary E, Herbrich, Shelley M, Cheng, Tiewei, Patterson, LaNisha L, Aitken, Marisa J L, Bhalla, Kapil, You, M James, Konopleva, Marina, Zweidler-McKay, Patrick A, Chandra, Joya

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Notch pathway activation induces neuroblastoma tumor cell growth arrest von Zage, Peter E., Nolo, Riitta, Fang, Wendy, Stewart, John, Garcia-Manero, Guillermo, Zweidler-McKay, Patrick A.

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Signaling of ERBB receptor tyrosine kinases promotes neuroblastoma growth in vitro and in vivo von Richards, Kristen N., Zweidler‐McKay, Patrick A., Van Roy, Nadine, Speleman, Frank, Trevino, Jesus, Zage, Peter E., Hughes, Dennis P. M.

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