Uncoupling DNA damage from chromatin damage to detoxify doxorubicin von Qiao, Xiaohang, van der Zanden, Sabina Y., Wander, Dennis P. A., Borràs, Daniel M., Song, Ji-Ying, Li, Xiaoyang, van Duikeren, Suzanne, van Gils, Noortje, Rutten, Arjo, van Herwaarden, Tessa, van Tellingen, Olaf, Giacomelli, Elisa, Bellin, Milena, Orlova, Valeria, Tertoolen, Leon G. J., Gerhardt, Sophie, Akkermans, Jimmy J., Bakker, Jeroen M., Zuur, Charlotte L., Pang, Baoxu, Smits, Anke M., Mummery, Christine L., Smith, Linda, Arens, Ramon, Li, Junmin, Overkleeft, Hermen S., Neefjes, Jacques

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Clinical-genomic determinants of immune checkpoint blockade response in head and neck squamous cell carcinoma von Valero, Cristina, Golkaram, Mahdi, Vos, Joris L, Xu, Bin, Fitzgerald, Conall, Lee, Mark, Kaplan, Shannon, Han, Catherine Y, Pei, Xin, Sarkar, Reith, Boe, Lillian A, Pandey, Abhinav, Koh, Elizabeth S, Zuur, Charlotte L, Solit, David B, Pawlowski, Traci, Liu, Li, Ho, Alan L, Chowell, Diego, Riaz, Nadeem, Chan, Timothy A, Morris, Luc Gt

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Prognostic role of tumor infiltrating lymphocytes in EBV positive and EBV negative nasopharyngeal carcinoma von Ooft, Marc L, van Ipenburg, Jolique A, Braunius, Weibel W, Zuur, Charlotte I, Koljenović, Senada, Willems, Stefan M

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A pan-cancer analysis of the microbiome in metastatic cancer von Battaglia, Thomas W., Mimpen, Iris L., Traets, Joleen J.H., van Hoeck, Arne, Zeverijn, Laurien J., Geurts, Birgit S., de Wit, Gijs F., Noë, Michaël, Hofland, Ingrid, Vos, Joris L., Cornelissen, Sten, Alkemade, Maartje, Broeks, Annegien, Zuur, Charlotte L., Cuppen, Edwin, Wessels, Lodewyk, van de Haar, Joris, Voest, Emile

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Spatial relationships in the urothelial and head and neck tumor microenvironment predict response to combination immune checkpoint inhibitors von Gil-Jimenez, Alberto, van Dijk, Nick, Vos, Joris L., Lubeck, Yoni, van Montfoort, Maurits L., Peters, Dennis, Hooijberg, Erik, Broeks, Annegien, Zuur, Charlotte L., van Rhijn, Bas W. G., Vis, Daniel J., van der Heijden, Michiel S., Wessels, Lodewyk F. A.

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Diversifying the anthracycline class of anti-cancer drugs identifies aclarubicin for superior survival of acute myeloid leukemia patients von Qiao, Xiaohang, van der Zanden, Sabina Y, Li, Xiaoyang, Tan, Minkang, Zhang, Yunxiang, Song, Ji-Ying, van Gelder, Merle A, Hamoen, Feija L, Janssen, Lennert, Zuur, Charlotte L, Pang, Baoxu, van Tellingen, Olaf, Li, Junmin, Neefjes, Jacques

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Immuno-radiotherapy with cetuximab and avelumab for advanced stage head and neck squamous cell carcinoma: Results from a phase-I trial von Elbers, Joris B.W., Al-Mamgani, Abrahim, Tesseslaar, Margot E.T., van den Brekel, Michiel W.M., Lange, Charlotte A.H., van der Wal, Jacqueline E., Verheij, Marcel, Zuur, Charlotte L., de Boer, Jan Paul

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[18F]FDG-PET accurately identifies pathological response early upon neoadjuvant immune checkpoint blockade in head and neck squamous cell carcinoma von Vos, Joris L., Zuur, Charlotte L., Smit, Laura A., de Boer, Jan Paul, Al-Mamgani, Abrahim, van den Brekel, Michiel W. M., Haanen, John B. A. G., Vogel, Wouter V.

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Activated neutrophils exert myeloid-derived suppressor cell activity damaging T cells beyond repair von Aarts, Cathelijn E.M., Hiemstra, Ida H., Béguin, Eelke P., Hoogendijk, Arjan J., Bouchmal, Souhailla, van Houdt, Michel, Tool, Anton T.J., Mul, Erik, Jansen, Machiel H., Janssen, Hans, van Alphen, Floris P.J., de Boer, Jan-Paul, Zuur, Charlotte L., Meijer, Alexander B., van den Berg, Timo K., Kuijpers, Taco W.

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The role of genetic variants in the prediction of hearing loss due to cisplatin chemoradiotherapy von Duinkerken, Charlotte W., Chiodo, Sabrina, Hueniken, Katrina, Hauptmann, Michael, Jóźwiak, Katarzyna, Cheng, Dangxiao, Hope, Andrew, Liu, Geoffrey, Zuur, Charlotte L.

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Nivolumab plus ipilimumab in advanced salivary gland cancer: a phase 2 trial von Vos, Joris L., Burman, Bharat, Jain, Swati, Fitzgerald, Conall W. R., Sherman, Eric J., Dunn, Lara A., Fetten, James V., Michel, Loren S., Kriplani, Anuja, Ng, Kenneth K., Eng, Juliana, Tchekmedyian, Vatche, Haque, Sofia, Katabi, Nora, Kuo, Fengshen, Han, Catherine Y., Nadeem, Zaineb, Yang, Wei, Makarov, Vladimir, Srivastava, Raghvendra M., Ostrovnaya, Irina, Prasad, Manu, Zuur, Charlotte L., Riaz, Nadeem, Pfister, David G., Klebanoff, Christopher A., Chan, Timothy A., Ho, Alan L., Morris, Luc G. T.

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Characterization of the tumor immune microenvironment in human papillomavirus-positive and -negative head and neck squamous cell carcinomas von Succaria, Farah, Kvistborg, Pia, Stein, Julie E., Engle, Elizabeth L., McMiller, Tracee L., Rooper, Lisa M., Thompson, Elizabeth, Berger, Alan E., van den Brekel, Michiel, Zuur, Charlotte L., Haanen, John, Topalian, Suzanne L., Taube, Janis M.

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Surgical outcomes of lymph node dissections for stage III melanoma after neoadjuvant systemic therapy are not inferior to upfront surgery von Zijlker, Lisanne P., van der Burg, Stijn J.C., Blank, Christian U., Zuur, Charlotte L., Klop, W. Martin C., Wouters, Michel W.M.J., van Houdt, Winan J., van Akkooi, Alexander C.J.

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Salvage Surgery for Recurrence after Radiotherapy for Squamous Cell Carcinoma of the Head and Neck von Elbers, Joris B. W., Al-Mamgani, Abrahim, van den Brekel, Michiel W. M., Jóźwiak, Katarzyna, de Boer, J. P., Lohuis, Peter J. F. M., Willems, Stefan M., Verheij, Marcel, Zuur, Charlotte L.

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Dual immune checkpoint blockade induces analogous alterations in the dysfunctional CD8+ T cell and activated Treg compartment von van der Leun, Anne M, Traets, Joleen J H, Vos, Joris L, Elbers, Joris B W, Patiwael, Sanne, Qiao, Xiaohang, Machuca-Ostos, Mercedes, Thommen, Daniela S, Haanen, John B A G, Schumacher, Ton N M, Zuur, Charlotte L

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Reduction of GTV to high-risk CTV radiation margin in head and neck squamous cell carcinoma significantly reduced acute and late radiation-related toxicity with comparable outcomes von Al-Mamgani, Abrahim, Kessels, Rob, Navran, Arash, Hamming-Vrieze, Olga, Zuur, Charlotte L., Paul de Boer, Jan, Jonker, Marcel C.J., Janssen, Tomas, Sonke, Jan-Jakob, Marijnen, Corrie A.M.

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Representativeness of the Index Lymph Node for Total Nodal Basin in Pathologic Response Assessment After Neoadjuvant Checkpoint Inhibitor Therapy in Patients With Stage III Melanom... von Reijers, Irene L. M, Rawson, Robert V, Colebatch, Andrew J, Rozeman, Elisa A, Menzies, Alex M, van Akkooi, Alexander C. J, Shannon, Kerwin F, Wouters, Michel W, Saw, Robyn P. M, van Houdt, Winan J, Zuur, Charlotte L, Nieweg, Omgo E, Ch’ng, Sydney, Klop, W. Martin C, Spillane, Andrew J, Long, Georgina V, Scolyer, Richard A, van de Wiel, Bart A, Blank, Christian U

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Neoadjuvant immunotherapy with nivolumab and ipilimumab induces major pathological responses in patients with head and neck squamous cell carcinoma von Vos, Joris L., Elbers, Joris B. W., Krijgsman, Oscar, Traets, Joleen J. H., Qiao, Xiaohang, van der Leun, Anne M., Lubeck, Yoni, Seignette, Iris M., Smit, Laura A., Willems, Stefan M., van den Brekel, Michiel W. M., Dirven, Richard, Baris Karakullukcu, M., Karssemakers, Luc, Klop, W. Martin C., Lohuis, Peter J. F. M., Schreuder, Willem H., Smeele, Ludi E., van der Velden, Lilly-Ann, Bing Tan, I., Onderwater, Suzanne, Jasperse, Bas, Vogel, Wouter V., Al-Mamgani, Abrahim, Keijser, Astrid, van der Noort, Vincent, Broeks, Annegien, Hooijberg, Erik, Peeper, Daniel S., Schumacher, Ton N., Blank, Christian U., de Boer, Jan Paul, Haanen, John B. A. G., Zuur, Charlotte L.

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The association between skeletal muscle mass and sensorineural hearing loss upon cisplatin‐based chemoradiotherapy in patients with head and neck squamous cell carcinoma von Schaeffers, Anouk W. M. A., Burger, Anouk V. M., Duinkerken, Charlotte W., Sluis, Klaske E., Boer, Jan Paul, Molen, Lisette, Hoetink, Alex E., Al‐Mamgani, Abrahim, Jóźwiak, Katarzyna, Devriese, Lot A., Bree, Remco, Zuur, Charlotte L.

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T-VEC for stage IIIB-IVM1a melanoma achieves high rates of complete and durable responses and is associated with tumor load: a clinical prediction model von Stahlie, Emma H. A., Franke, Viola, Zuur, Charlotte L., Klop, Willem M. C., van der Hiel, Bernies, Van de Wiel, Bart A., Wouters, Michel W. J. M., Schrage, Yvonne M., van Houdt, Winan J., van Akkooi, Alexander C. J.

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