Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage von Komor, Alexis C., Kim, Yongjoo B., Packer, Michael S., Zuris, John A., Liu, David R.

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Efficient delivery of genome-editing proteins using bioreducible lipid nanoparticles von Wang, Ming, Zuris, John A., Meng, Fantao, Rees, Holly, Sun, Shuo, Deng, Pu, Han, Yong, Gao, Xue, Pouli, Dimitra, Wu, Qi, Georgakoudi, Irene, Liu, David R., Xu, Qiaobing

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Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo von Zuris, John A, Thompson, David B, Shu, Yilai, Guilinger, John P, Bessen, Jeffrey L, Hu, Johnny H, Maeder, Morgan L, Joung, J Keith, Chen, Zheng-Yi, Liu, David R

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Small molecule–triggered Cas9 protein with improved genome-editing specificity von Davis, Kevin M, Pattanayak, Vikram, Thompson, David B, Zuris, John A, Liu, David R

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AsCas12a ultra nuclease facilitates the rapid generation of therapeutic cell medicines von Zhang, Liyang, Zuris, John A., Viswanathan, Ramya, Edelstein, Jasmine N., Turk, Rolf, Thommandru, Bernice, Rube, H. Tomas, Glenn, Steve E., Collingwood, Michael A., Bode, Nicole M., Beaudoin, Sarah F., Lele, Swarali, Scott, Sean N., Wasko, Kevin M., Sexton, Steven, Borges, Christopher M., Schubert, Mollie S., Kurgan, Gavin L., McNeill, Matthew S., Fernandez, Cecilia A., Myer, Vic E., Morgan, Richard A., Behlke, Mark A., Vakulskas, Christopher A.

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Continuous directed evolution of DNA-binding proteins to improve TALEN specificity von Hubbard, Basil P, Badran, Ahmed H, Zuris, John A, Guilinger, John P, Davis, Kevin M, Chen, Liwei, Tsai, Shengdar Q, Sander, Jeffry D, Joung, J Keith, Liu, David R

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Treatment of monogenic and digenic dominant genetic hearing loss by CRISPR-Cas9 ribonucleoprotein delivery in vivo von Tao, Yong, Lamas, Veronica, Du, Wan, Zhu, Wenliang, Li, Yiran, Whittaker, Madelynn N., Zuris, John A., Thompson, David B., Rameshbabu, Arun Prabhu, Shu, Yilai, Gao, Xue, Hu, Johnny H., Pei, Charles, Kong, Wei-Jia, Liu, Xuezhong, Wu, Hao, Kleinstiver, Benjamin P., Liu, David R., Chen, Zheng-Yi

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Nutrient-deprivation autophagy factor-1 (NAF-1): biochemical properties of a novel cellular target for anti-diabetic drugs von Tamir, Sagi, Zuris, John A, Agranat, Lily, Lipper, Colin H, Conlan, Andrea R, Michaeli, Dorit, Harir, Yael, Paddock, Mark L, Mittler, Ron, Cabantchik, Zvi Ioav, Jennings, Patricia A, Nechushtai, Rachel

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A highly efficient transgene knock-in technology in clinically relevant cell types von Allen, Alexander G., Khan, Samia Q., Margulies, Carrie M., Viswanathan, Ramya, Lele, Swarali, Blaha, Laura, Scott, Sean N., Izzo, Kaitlyn M., Gerew, Alexandra, Pattali, Rithu, Cochran, Nadire R., Holland, Carl S., Zhao, Amy H., Sherman, Stephen E., Jaskolka, Michael C., Wu, Meng, Wilson, Aaron C., Sun, Xiaoqi, Ciulla, Dawn M., Zhang, Deric, Nelson, Jacqueline D., Zhang, Peisheng, Mazzucato, Patrizia, Huang, Yan, Giannoukos, Georgia, Marco, Eugenio, Nehil, Michael, Follit, John A., Chang, Kai-Hsin, Shearman, Mark S., Wilson, Christopher J., Zuris, John A.

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Facile transfer of [2Fe-2S] clusters from the diabetes drug target mitoNEET to an apo-acceptor protein von Zuris, John A, Harir, Yael, Conlan, Andrea R, Shvartsman, Maya, Michaeli, Dorit, Tamir, Sagi, Paddock, Mark L, Onuchic, José N, Mittler, Ron, Cabantchik, Zvi Ioav, Jennings, Patricia A, Nechushtai, Rachel

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Integrated strategy reveals the protein interface between cancer targets Bcl-2 and NAF-1 von Tamir, Sagi, Rotem-Bamberger, Shahar, Katz, Chen, Morcos, Faruck, Hailey, Kendra L., Zuris, John A., Wang, Charles, Conlan, Andrea R., Lipper, Colin H., Paddock, Mark L., Mittler, Ron, Onuchic, José N., Jennings, Patricia A., Friedler, Assaf, Nechushtai, Rachel

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Characterization of Arabidopsis NEET Reveals an Ancient Role for NEET Proteins in Iron Metabolism von Nechushtai, Rachel, Conlan, Andrea R., Harir, Yael, Song, Luhua, Yogev, Ohad, Eisenberg-Domovich, Yael, Livnah, Oded, Michaeli, Dorit, Rosen, Rachel, Ma, Vincent, Luo, Yuting, Zuris, John A., Paddock, Mark L., Cabantchik, Zvi Ioav, Jennings, Patricia A., Mittler, Ron

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Author Correction: AsCas12a ultra nuclease facilitates the rapid generation of therapeutic cell medicines von Zhang, Liyang, Zuris, John A., Viswanathan, Ramya, Edelstein, Jasmine N., Turk, Rolf, Thommandru, Bernice, Rube, H. Tomas, Glenn, Steve E., Collingwood, Michael A., Bode, Nicole M., Beaudoin, Sarah F., Lele, Swarali, Scott, Sean N., Wasko, Kevin M., Sexton, Steven, Borges, Christopher M., Schubert, Mollie S., Kurgan, Gavin L., McNeill, Matthew S., Fernandez, Cecilia A., Myer, Vic E., Morgan, Richard A., Behlke, Mark A., Vakulskas, Christopher A.

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Redox Characterization of the FeS Protein MitoNEET and Impact of Thiazolidinedione Drug Binding von Bak, Daniel W, Zuris, John A, Paddock, Mark L, Jennings, Patricia A, Elliott, Sean J

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NADPH Inhibits [2Fe-2S] Cluster Protein Transfer from Diabetes Drug Target MitoNEET to an Apo-acceptor Protein von Zuris, John A., Ali, Syed S., Yeh, Howard, Nguyen, Tung A., Nechushtai, Rachel, Paddock, Mark L., Jennings, Patricia A.

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Allosteric control in a metalloprotein dramatically alters function von Baxter, Elizabeth Leigh, Zuris, John A., Wang, Charles, Vo, Phu Luong T., Axelrod, Herbert L., Cohen, Aina E., Paddock, Mark L., Nechushtai, Rachel, Onuchic, Jose N., Jennings, Patricia A.

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Selection by essential-gene exon knock-in for the generation of efficient cell therapies

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Allostery in the ferredoxin protein motif does not involve a conformational switch von Nechushtai, Rachel, Lammert, Heiko, Michaeli, Dorit, Eisenberg-Domovich, Yael, Zuris, John A, Luca, Maria A, Capraro, Dominique T, Fish, Alex, Shimshon, Odelia, Roy, Melinda, Schug, Alexander, Whitford, Paul C, Livnah, Oded, Onuchic, José N, Jennings, Patricia A

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191 GAPDH knock-in of high affinity CD16 in iPSC derived NK cells drives high-level expression and increased anti-tumor function von Pattali, Rithu, Izzo, Kaitlyn, Goncz, Edward, Sexton, Steven, Wasko, Kevin, Zuris, John, Nehil, Michael, Zhang, Kate, Shearman, Mark, Chang, Kai-Hsin, Allen, Alexander

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Engineering the Redox Potential over a Wide Range within a New Class of FeS Proteins von Zuris, John A, Halim, Danny A, Conlan, Andrea R, Abresch, Edward C, Nechushtai, Rachel, Paddock, Mark L, Jennings, Patricia A

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