CaMKK2 in myeloid cells is a key regulator of the immune-suppressive microenvironment in breast cancer von Racioppi, Luigi, Nelson, Erik R., Huang, Wei, Mukherjee, Debarati, Lawrence, Scott A., Lento, William, Masci, Anna Maria, Jiao, Yiquin, Park, Sunghee, York, Brian, Liu, Yaping, Baek, Amy E., Drewry, David H., Zuercher, William J., Bertani, Francesca R., Businaro, Luca, Geradts, Joseph, Hall, Allison, Means, Anthony R., Chao, Nelson, Chang, Ching-yi, McDonnell, Donald P.

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The Metabolic Regulator ERRα, a Downstream Target of HER2/IGF-1R, as a Therapeutic Target in Breast Cancer von Chang, Ching-yi, Kazmin, Dmitri, Jasper, Jeff S., Kunder, Rebecca, Zuercher, William J., McDonnell, Donald P.

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Overcoming Fungal Echinocandin Resistance through Inhibition of the Non-essential Stress Kinase Yck2 von Caplan, Tavia, Lorente-Macías, Álvaro, Stogios, Peter J., Evdokimova, Elena, Hyde, Sabrina, Wellington, Melanie A., Liston, Sean, Iyer, Kali R., Puumala, Emily, Shekhar-Guturja, Tanvi, Robbins, Nicole, Savchenko, Alexei, Krysan, Damian J., Whitesell, Luke, Zuercher, William J., Cowen, Leah E.

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Covalent inhibitors of EGFR family protein kinases induce degradation of human Tribbles 2 (TRIB2) pseudokinase in cancer cells von Foulkes, Daniel M, Byrne, Dominic P, Yeung, Wayland, Shrestha, Safal, Bailey, Fiona P, Ferries, Samantha, Eyers, Claire E, Keeshan, Karen, Wells, Carrow, Drewry, David H, Zuercher, William J, Kannan, Natarajan, Eyers, Patrick A

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Utilizing comprehensive and mini-kinome panels to optimize the selectivity of quinoline inhibitors for cyclin G associated kinase (GAK) von Asquith, Christopher R.M., Treiber, Daniel K., Zuercher, William J.

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Profile of the GSK published protein kinase inhibitor set across ATP-dependent and-independent luciferases: implications for reporter-gene assays von Dranchak, Patricia, MacArthur, Ryan, Guha, Rajarshi, Zuercher, William J, Drewry, David H, Auld, Douglas S, Inglese, James

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EGFR inhibitors identified as a potential treatment for chordoma in a focused compound screen von Scheipl, Susanne, Barnard, Michelle, Cottone, Lucia, Jorgensen, Mette, Drewry, David H, Zuercher, William J, Turlais, Fabrice, Ye, Hongtao, Leite, Ana P, Smith, James A, Leithner, Andreas, Möller, Peter, Brüderlein, Silke, Guppy, Naomi, Amary, Fernanda, Tirabosco, Roberto, Strauss, Sandra J, Pillay, Nischalan, Flanagan, Adrienne M

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SGC-GAK-1: A Chemical Probe for Cyclin G Associated Kinase (GAK) von Asquith, Christopher R. M, Berger, Benedict-Tilman, Wan, Jing, Bennett, James M, Capuzzi, Stephen J, Crona, Daniel J, Drewry, David H, East, Michael P, Elkins, Jonathan M, Fedorov, Oleg, Godoi, Paulo H, Hunter, Debra M, Knapp, Stefan, Müller, Susanne, Torrice, Chad D, Wells, Carrow I, Earp, H. Shelton, Willson, Timothy M, Zuercher, William J

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Estrogen-related receptor-α is a metabolic regulator of effector T-cell activation and differentiation von Michalek, Ryan D, Gerriets, Valerie A, Nichols, Amanda G, Inoue, Makoto, Kazmin, Dmitri, Chang, Ching-Yi, Dwyer, Mary A, Nelson, Erik R, Pollizzi, Kristen N, Ilkayeva, Olga, Giguere, Vincent, Zuercher, William J, Powell, Jonathan D, Shinohara, Mari L, McDonnell, Donald P, Rathmell, Jeffrey C

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Design of a Cyclin G Associated Kinase (GAK)/Epidermal Growth Factor Receptor (EGFR) Inhibitor Set to Interrogate the Relationship of EGFR and GAK in Chordoma von Asquith, Christopher R. M, Naegeli, Kaleb M, East, Michael P, Laitinen, Tuomo, Havener, Tammy M, Wells, Carrow I, Johnson, Gary L, Drewry, David H, Zuercher, William J, Morris, David C

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The Intersection of Structural and Chemical Biology - An Essential Synergy von Zuercher, William J., Elkins, Jonathan M., Knapp, Stefan

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Using a Genetically Encoded Sensor to Identify Inhibitors of Toxoplasma gondii Ca2+ Signaling von Sidik, Saima M., Hortua Triana, Miryam A., Paul, Aditya S., El Bakkouri, Majida, Hackett, Caroline G., Tran, Fanny, Westwood, Nicholas J., Hui, Raymond, Zuercher, William J., Duraisingh, Manoj T., Moreno, Silvia N.J., Lourido, Sebastian

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Identification of drug modifiers for RYR1-related myopathy using a multi-species discovery pipeline von Volpatti, Jonathan R, Endo, Yukari, Knox, Jessica, Groom, Linda, Brennan, Stephanie, Noche, Ramil, Zuercher, William J, Roy, Peter, Dirksen, Robert T, Dowling, James J

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New Insights into 4-Anilinoquinazolines as Inhibitors of Cardiac Troponin I-Interacting Kinase (TNNi3K) von Asquith, Christopher R M, Laitinen, Tuomo, Wells, Carrow I, Tizzard, Graham J, Zuercher, William J

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In Depth Analysis of Kinase Cross Screening Data to Identify CAMKK2 Inhibitory Scaffolds von O'Byrne, Sean N, Scott, John W, Pilotte, Joseph R, Santiago, André da S, Langendorf, Christopher G, Oakhill, Jonathan S, Eduful, Benjamin J, Couñago, Rafael M, Wells, Carrow I, Zuercher, William J, Willson, Timothy M, Drewry, David H

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Structure-Bioactivity Relationship for Benzimidazole Thiophene Inhibitors of Polo-Like Kinase 1 (PLK1), a Potential Drug Target in Schistosoma mansoni von Long, Thavy, Neitz, R Jeffrey, Beasley, Rachel, Kalyanaraman, Chakrapani, Suzuki, Brian M, Jacobson, Matthew P, Dissous, Colette, McKerrow, James H, Drewry, David H, Zuercher, William J, Singh, Rahul, Caffrey, Conor R

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Identification and Optimization of 4‐Anilinoquinolines as Inhibitors of Cyclin G Associated Kinase von Asquith, Christopher R. M., Laitinen, Tuomo, Bennett, James M., Godoi, Paulo H., East, Michael P., Tizzard, Graham J., Graves, Lee M., Johnson, Gary L., Dornsife, Ronna E., Wells, Carrow I., Elkins, Jonathan M., Willson, Timothy M., Zuercher, William J.

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Towards the Development of an In vivo Chemical Probe for Cyclin G Associated Kinase (GAK) von Asquith, Christopher R M, Bennett, James M, Su, Lianyong, Laitinen, Tuomo, Elkins, Jonathan M, Pickett, Julie E, Wells, Carrow I, Li, Zengbiao, Willson, Timothy M, Zuercher, William J

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Design and Analysis of the 4‐Anilinoquin(az)oline Kinase Inhibition Profiles of GAK/SLK/STK10 Using Quantitative Structure‐Activity Relationships von Asquith, Christopher R. M., Laitinen, Tuomo, Bennett, James M., Wells, Carrow I., Elkins, Jonathan M., Zuercher, William J., Tizzard, Graham J., Poso, Antti

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Identification of lead anti-human cytomegalovirus compounds targeting MAP4K4 via machine learning analysis of kinase inhibitor screening data von Strang, Blair L, Asquith, Christopher R M, Moshrif, Hanan F, Ho, Catherine M-K, Zuercher, William J, Al-Ali, Hassan

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