Uniformly modified 2'-deoxy-2'-fluoro-phosphorothioate oligonucleotides as nuclease-resistant antisense compounds with high affinity and specificity for RNA targets von Kawasaki, Andrew M, Casper, Martin D, Freier, Susan M, Lesnik, Elena A, Zounes, Maryann C, Cummins, Lendell L, Gonzalez, Carolyn, Cook, P. Dan

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Effects of phosphorothioate capping on antivense oligonucleotide stability, hybridization and antiviral efficacy versus herpes simplex virus infection von Hoke, Glenn D., Draper, Kenneth, Freier, Susan M., Gonzalez, Carolyn, Driver, Vickie B., Zounes, Maryann C., Ecker, David J.

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Antisense oligodeoxynucleotides: synthesis, biophysical and biological evaluation of oligodeoxynucleotides containing modified pyrimidines von Sanghvi, Yogesh S., Hoke, Glenn D., Freier, Susan M., Zounes, Maryann C., Gonzalez, Carolyn, Cummins, Lendell, Sasmor, Henri, Cook, P.Dan

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Characterization of three forms of rabbit microsomal cytochrome P-450 by peptide mapping utilizing limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis von Johnson, Eric F., Zounes, Maryann C., Muller-Eberhard, Ursula

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Oligodeoxynucleotides containing 2'-O-modified adenosine: Synthesis and effects on stability of DNA:RNA duplexes von Lesnik, Elena A, Guinosso, Charles J, Kawasaki, Andrew M, Sasmor, Henri, Zounes, Maryann, Cummins, Lendell L, Ecker, David J, Cook, P. Dan, Freier, Susan M

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Remarkable enhancement of binding affinity of Heterocycle-modified DNA to DNA and RNA. Synthesis, characterization and biophysical evaluation of N 2-imidazolylpropylguanine and N 2... von Ramasamy, Kanda S., Zounes, Maryann, Gonzalez, Carolyn, Freier, Susan M., Lesnik, Elena A., Cummins, Lendell L., Griffey, Richard H., Monia, Brett P., Dan Cook, P.

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Remarkable enhancement of binding affinity of heterocycle-modified DNA to DNA and RNA. Synthesis, characterization and biophysical evaluation of N2- imidazolylpropylguanine and N2-... von RAMASAMY, K. S, ZOUNES, M, GONZALEZ, C, FREIER, S. M, LESNIK, E. A, CUMMINS, L. L, GRIFFEY, R. H, MONIA, B. P, COOK, P. D

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