Mutant KRAS is a druggable target for pancreatic cancer von Khvalevsky, Elina Zorde, Gabai, Racheli, Rachmut, Itzhak Haim, Horwitz, Elad, Brunschwig, Zivia, Orbach, Ariel, Shemi, Adva, Golan, Talia, Domb, Abraham J., Yavin, Eylon, Giladi, Hilla, Rivkin, Ludmila, Simerzin, Alina, Eliakim, Rami, Khalaileh, Abed, Hubert, Ayala, Lahav, Maor, Kopelman, Yael, Goldin, Eran, Dancour, Alan, Hants, Yael, Arbel-Alon, Sagit, Abramovitch, Rinat, Shemi, Amotz, Galun, Eithan

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The liver‐specific microRNA‐122, the complementary strand of microRNA‐122, acts as a tumor suppressor by modulating the p53/mouse double minute 2 homolog circuitry von Simerzin, Alina, Zorde‐Khvalevsky, Elina, Rivkin, Mila, Adar, Revital, Zucman‐Rossi, Jessica, Couchy, Gabrielle, Roskams, Tania, Govaere, Olivier, Oren, Moshe, Giladi, Hilla, Galun, Eithan

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Preclinical Safety Evaluation in Rats of a Polymeric Matrix Containing an siRNA Drug Used as a Local and Prolonged Delivery System for Pancreatic Cancer Therapy von Ramot, Yuval, Rotkopf, Shay, Gabai, Rachel Malka, Zorde Khvalevsky, Elina, Muravnik, Sofia, Marzoli, Gabriela Alejandra, Domb, Abraham J., Shemi, Amotz, Nyska, Abraham

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Incomplete thermal ablation of tumors promotes increased tumorigenesis von Markezana, Aurelia, Goldberg, S. Nahum, Kumar, Gaurav, Zorde-Khvalevsky, Elina, Gourevtich, Svetlana, Rozenblum, Nir, Galun, Eithan, Ahmed, Muneeb

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Fibroblast growth factors induce hepatic tumorigenesis post radiofrequency ablation von Markezana, Aurelia, Paldor, Mor, Liao, Haixing, Ahmed, Muneeb, Zorde-Khvalevsky, Elina, Rozenblum, Nir, Stechele, Matthias, Salvermoser, Lukas, Laville, Flinn, Goldmann, Salome, Rosenberg, Nofar, Andrasina, Tomas, Ricke, Jens, Galun, Eithan, Goldberg, Shraga Nahum

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Moderate hyperthermic heating encountered during thermal ablation increases tumor cell activity von Markezana, Aurelia, Ahmed, Muneeb, Kumar, Gaurav, Zorde-Khvalevsky, Elina, Rozenblum, Nir, Galun, Eithan, Goldberg, S. Nahum

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DSP107 combines inhibition of CD47/SIRPα axis with activation of 4-1BB to trigger anticancer immunity von Cendrowicz, Ewa, Jacob, Lisa, Greenwald, Shirley, Tamir, Ami, Pecker, Iris, Tabakman, Rinat, Ghantous, Lucy, Tamir, Liat, Kahn, Roy, Avichzer, Jasmine, Aronin, Alexandra, Amsili, Shira, Zorde-Khvalevsky, Elina, Gozlan, Yosi, Vlaming, Martijn, Huls, Gerwin, van Meerten, Tom, Dranitzki, Michal Elhalel, Foley-Comer, Adam, Pereg, Yaron, Peled, Amnon, Chajut, Ayelet, Bremer, Edwin

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Multistep, effective drug distribution within solid tumors von Shemi, Amotz, Khvalevsky, Elina Zorde, Gabai, Rachel Malka, Domb, Abraham, Barenholz, Yechezkel

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Toll‐like receptor 3 signaling attenuates liver regeneration von Zorde‐Khvalevsky, Elina, Abramovitch, Rinat, Barash, Hila, Spivak‐Pohis, Irit, Rivkin, Ludmila, Rachmilewitz, Jacob, Galun, Eithan, Giladi, Hilla

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790 DSP502 — A novel approach for targeting TIGIT and PD1 pathways for cancer immunotherapy von Chajut, Ayelet, Greenwald, Shirley, Weber, Matthew, Tamir, Ami, Pecker, Iris, Tabakman, Rinat, Ganthous, Lucy, Tamir, Liat, Kahn, Roy, Avichzer, Jasmine, Aronin, Alexandra, Zorde-Khvalevsky, Elina, Peled, Amnon, Elhalel Dranitzki, Michal Michal, Foley-Comer, Adam, Tykocinski, Mark

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Metabolic Circuit Involving Free Fatty Acids, microRNA 122, and Triglyceride Synthesis in Liver and Muscle Tissues von Chai, Chofit, Rivkin, Mila, Berkovits, Liav, Simerzin, Alina, Zorde-Khvalevsky, Elina, Rosenberg, Nofar, Klein, Shiri, Yaish, Dayana, Durst, Ronen, Shpitzen, Shoshana, Udi, Shiran, Tam, Joseph, Heeren, Joerg, Worthmann, Anna, Schramm, Christoph, Kluwe, Johannes, Ravid, Revital, Hornstein, Eran, Giladi, Hilla, Galun, Eithan

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RNAi therapy targeting KRAS in combination with chemotherapy for locally advanced pancreatic cancer patients von Golan, Talia, Khvalevsky, Elina Zorde, Hubert, Ayala, Gabai, Rachel Malka, Hen, Naama, Segal, Amiel, Domb, Abraham, Harari, Gil, David, Eliel Ben, Raskin, Stephen, Goldes, Yuri, Goldin, Eran, Eliakim, Rami, Lahav, Maor, Kopleman, Yael, Dancour, Alain, Shemi, Amotz, Galun, Eithan

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Short treatment of peripheral blood cells product with Fas ligand using closed automated cell processing system significantly reduces immune cell reactivity of the graft in vitro a... von Rodionov, Galina, Rosenzwaig, Michal, Tzadok, Michal Schrift, Kvint, Moran, Gevir, Elazar, Zorde-Khvalevsky, Elina, Peled, Amnon, Yarkoni, Shai, Ofer, Amos

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Inflammation-Induced Expression and Secretion of MicroRNA 122 Leads to Reduced Blood Levels of Kidney-Derived Erythropoietin and Anemia von Rivkin, Mila, Simerzin, Alina, Zorde-Khvalevsky, Elina, Chai, Chofit, Yuval, Jonathan B, Rosenberg, Nofar, Harari-Steinfeld, Rona, Schneider, Ronen, Amir, Gail, Condiotti, Reba, Heikenwalder, Mathias, Weber, Achim, Schramm, Christoph, Wege, Henning, Kluwe, Johannes, Galun, Eithan, Giladi, Hilla

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The lncRNA H19-Derived MicroRNA-675 Promotes Liver Necroptosis by Targeting FADD von Harari-Steinfeld, Rona, Gefen, Maytal, Simerzin, Alina, Zorde-Khvalevsky, Elina, Rivkin, Mila, Ella, Ezra, Friehmann, Tomer, Gerlic, Mordechay, Zucman-Rossi, Jessica, Caruso, Stefano, Leveille, Mélissa, Estall, Jennifer L, Goldenberg, Daniel S, Giladi, Hilla, Galun, Eithan, Bromberg, Zohar

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THU-374-The INCRNA H19-dervied MIR-675 promotes liver necroptosis by targeting fadd von Galun, Eithan, Harai-Steinfeld, Rona, Gefen, Meytal, Simerzin, Alina, Zorde-Khvalevsky, Elina, Rivkin, Mila, Ella, Ezra, Friehmann, Tomer, Gerlic, Mordeachy, Zucman-Rossi, Jessica, Caruso, Stefano, Leveille, Melissa, Estall, Jennifer, Goldenberg, Daniel S, Giladi, Hilla, Bromberg, Zohar

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DSP107 combines inhibition of CD47/SIRP[alpha] axis with activation of 4-1BB to trigger anticancer immunity von Zorde-Khvalevsky, Elina, Kahn, Roy, Amsili, Shira, Tamir, Liat, Vlaming, Martijn, Chajut, Ayelet, Avichzer, Jasmine, Aronin, Alexandra, Tamir, Ami, Tabakman, Rinat, Huls, Gerwin, Gozlan, Yosi, Pereg, Yaron, Ghantous, Lucy, Cendrowicz, Ewa, Pecker, Iris, Bremer, Edwin, Jacob, Lisa, van Meerten, Tom, Foley-Comer, Adam, Greenwald, Shirley, Dranitzki, Michal Elhalel, Peled, Amnon

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Inflammation-Induced Expression and Secretion of MicroRNA 122 Leads to Reduced Blood Levels of Kidney-derived Erythropoietin and Anemia von Rivkin, Mila, Simerzin, Alina, Zorde-Khvalevsky, Elina, Chai, Chofit, Yuval, Jonathan B, Rosenberg, Nofar, Harari-Steinfeld, Rona, Schneider, Ronen, Amir, Gail, Condiotti, Reba, Heikenwalder, Mathias, Weber, Achim, Schramm, Christoph, Wege, Henning, Kluwe, Johannes, Galun, Eithan, Giladi, Hilla

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Novel Kras-directed therapy in combination with chemotherapy for locally advanced pancreatic adenocarcinoma von Golan, Talia, Hubert, Ayala, Shemi, Amotz, Segal, Amiel, Khvalevsky, Elina Zorde, Domb, Avi, Ben-David, Eliel, Raskin, Stephen, Goldes, Yuri, Lahav, Maor, Dancour, Alan, Galun, Eithan

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A phase I trial of a local delivery of siRNA against k-ras in combination with chemotherapy for locally advanced pancreatic adenocarcinoma von Golan, Talia, Hubert, Ayala, Shemi, Amotz, Segal, Amiel, Dancour, Alan, Khvalevsky, Elina Zorde, Ben-David, Eliel, Raskin, Stephen, Goldes, Yuri, Inbar, Yael, Lahav, Maor, Domb, Avi, Galun, Eithan

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