Reversible and regionally selective downregulation of brain cannabinoid CB1 receptors in chronic daily cannabis smokers von Hirvonen, J, Goodwin, R S, Li, C-T, Terry, G E, Zoghbi, S S, Morse, C, Pike, V W, Volkow, N D, Huestis, M A, Innis, R B

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The Inhibitor Ko143 Is Not Specific for ABCG2 von Weidner, Lora D, Zoghbi, Sami S, Lu, Shuiyu, Shukla, Suneet, Ambudkar, Suresh V, Pike, Victor W, Mulder, Jan, Gottesman, Michael M, Innis, Robert B, Hall, Matthew D

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Imaging the Function of P‐Glycoprotein With Radiotracers: Pharmacokinetics and In Vivo Applications von Kannan, P, John, C, Zoghbi, S S, Halldin, C, Gottesman, M M, Innis, R B, Hall, M D

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First-in-Human Evaluation of 18F-PF-06445974, a PET Radioligand That Preferentially Labels Phosphodiesterase-4B von Wakabayashi, Yuichi, Stenkrona, Per, Arakawa, Ryosuke, Yan, Xuefeng, Van Buskirk, Maia G, Jenkins, Madeline D, Santamaria, Jose A Montero, Maresca, Kevin P, Takano, Akihiro, Liow, Jeih-San, Chappie, Thomas A, Varrone, Andrea, Nag, Sangram, Zhang, Lei, Hughes, Zoë A, Schmidt, Christopher J, Doran, Shawn D, Mannes, Andrew, Zanotti-Fregonara, Paolo, Ooms, Maarten, Morse, Cheryl L, Zoghbi, Sami S, Halldin, Christer, Pike, Victor W, Innis, Robert B

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Retest imaging of [11C]NOP-1A binding to nociceptin/orphanin FQ peptide (NOP) receptors in the brain of healthy humans von Lohith, Talakad G., Zoghbi, Sami S., Morse, Cheryl L., Araneta, Maria D. Ferraris, Barth, Vanessa N., Goebl, Nancy A., Tauscher, Johannes T., Pike, Victor W., Innis, Robert B., Fujita, Masahiro

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Imaging and quantitation of cannabinoid CB1 receptors in human and monkey brains using (18)F-labeled inverse agonist radioligands von Terry, Garth E, Hirvonen, Jussi, Liow, Jeih-San, Zoghbi, Sami S, Gladding, Robert, Tauscher, Johannes T, Schaus, John M, Phebus, Lee, Felder, Christian C, Morse, Cheryl L, Donohue, Sean R, Pike, Victor W, Halldin, Christer, Innis, Robert B

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In vitro and in vivo evaluation of (11)C-SD5024, a novel PET radioligand for human brain imaging of cannabinoid CB1 receptors von Tsujikawa, Tetsuya, Zoghbi, Sami S, Hong, Jinsoo, Donohue, Sean R, Jenko, Kimberly J, Gladding, Robert L, Halldin, Christer, Pike, Victor W, Innis, Robert B, Fujita, Masahiro

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Quantitation of cannabinoid CB1 receptors in healthy human brain using positron emission tomography and an inverse agonist radioligand von Terry, Garth E., Liow, Jeih-San, Zoghbi, Sami S., Hirvonen, Jussi, Farris, Amanda G., Lerner, Alicja, Tauscher, Johannes T., Schaus, John M., Phebus, Lee, Felder, Christian C., Morse, Cheryl L., Hong, Jinsoo S., Pike, Victor W., Halldin, Christer, Innis, Robert B.

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Lysosomal trapping of a radiolabeled substrate of P-glycoprotein as a mechanism for signal amplification in PET von Kannan, Pavitra, Brimacombe, Kyle R, Kreisl, William C, Liow, Jeih-San, Zoghbi, Sami S, Telu, Sanjay, Zhang, Yi, Pike, Victor W, Halldin, Christer, Gottesman, Michael M, Innis, Robert B, Hall, Matthew D

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Synthesis and evaluation of two new candidate high-affinity full agonist PET radioligands for imaging 5-HT1B receptors von Lindberg, Anton, Lu, Shuiyu, Nag, Sangram, Schou, Magnus, Liow, Jeih-San, Zoghbi, Sami S., Frankland, Michael P., Gladding, Robert L., Morse, Cheryl L., Takano, Akihiro, Amini, Nahid, Elmore, Charles S., Lee, Yong Sok, Innis, Robert B., Halldin, Christer, Pike, Victor W.

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Synthesis and evaluation of two new candidate high-affinity full agonist PET radioligands for imaging 5-HT 1β receptors von Lindberg, A, Lu, S, Nag, S, Schou, M, Liow, J-S, Zoghbi, SS, Frankland, MP, Gladding, RL, Morse, CL, Takano, A

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Brain SPECT Imaging of Amphetamine-Induced Dopamine Release in Euthymic Bipolar Disorder Patients von Anand, Amit, Verhoeff, Paul, Seneca, Nicholas, Zoghbi, Sami S., Seibyl, John P., Charney, Dennis S., Innis, Robert B.

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Single Photon Emission Computerized Tomography Imaging of Amphetamine-Induced Dopamine Release in Drug-Free Schizophrenic Subjects von Laruelle, Marc, Abi-Dargham, Anissa, Van Dyck, Christopher H., Gil, Roberto, D'Souza, Cyril D., Erdos, Joseph, McCance, Elinore, Rosenblatt, William, Fingado, Christine, Zoghbi, Sami S., Baldwin, Ronald M., Seibyl, John P., Krystal, John H., Charney, Dennis S., Innis, Robert B.

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N-desmethyl-Loperamide Is Selective for P-Glycoprotein among Three ATP-Binding Cassette Transporters at the Blood-Brain Barrier von KANNAN, Pavitra, BRIMACOMBE, Kyle R, HALL, Matthew D, ZOGHBI, Sami S, LIOW, Jeih-San, MORSE, Cheryl, TAKU, Andrew K, PIKE, Victor W, HALLDIN, Christer, INNIS, Robert B, GOTTESMAN, Michael M

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Widespread decrease of nicotinic acetylcholine receptors in Parkinson's disease von Fujita, Masahiro, Ichise, Masanori, Zoghbi, Sami S., Liow, Jeih-San, Ghose, Subroto, Vines, Douglass C., Sangare, Janet, Lu, Jian-Qiang, Cropley, Vanessa L., Iida, Hidehiro, Kim, Kyeong Min, Cohen, Robert M., Bara-Jimenez, William, Ravina, Bernard, Innis, Robert B.

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The PET Radioligand [11C]MePPEP Binds Reversibly and with High Specific Signal to Cannabinoid CB1 Receptors in Nonhuman Primate Brain von YASUNO, Fumihiko, BROWN, Amira K, GLADDING, Robert L, HONG, Jinsoo, HALLDIN, Christer, PIKE, Victor W, INNIS, Robert B, ZOGHBI, Sami S, KRUSHINSKI, Joseph H, CHERNET, Eyassu, TAUSCHER, Johannes, SCHAUS, John M, PHEBUS, Lee A, CHESTERFIELD, Amy K, FELDER, Christian C

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Identification and regional distribution in rat brain of radiometabolites of the dopamine transporter PET radioligand [11C]PE2I von Shetty, H Umesha, Zoghbi, Sami S, Liow, Jeih-San, Ichise, Masanori, Hong, Jinsoo, Musachio, John L, Halldin, Christer, Seidel, Jurgen, Innis, Robert B, Pike, Victor W

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11 C-CUMI-101, a PET Radioligand, Behaves as a Serotonin 1A Receptor Antagonist and Also Binds to α 1 Adrenoceptors in Brain von Shrestha, Stal Saurav, Liow, Jeih-San, Lu, Shuiyu, Jenko, Kimberly, Gladding, Robert L., Svenningsson, Per, Morse, Cheryl L., Zoghbi, Sami S., Pike, Victor W., Innis, Robert B.

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In vitro and in vivo evaluation of 11 C-SD5024, a novel PET radioligand for human brain imaging of cannabinoid CB 1 receptors von Tsujikawa, T, Zoghbi, SS, Hong, J, Donohue, SR, Jenko, KJ, Gladding, RL, Halldin, C, Pike, VW, Innis, RB, Fujita, M

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[123I]β/CIT/SPECT imaging demonstrates bilateral loss of dopamine transporters in hemi-Parkinson's disease von MAREK, K. L, SEIBYL, J. P, ZOGHBI, S. S, ZEA-PONCE, Y, BALDWIN, R. M, FUSSELL, B, CHARNEY, D. S, VAN DYCK, C, HOFFER, P. B, INNIS, R. B

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