Next-generation risk assessment read-across case study: application of a 10-step framework to derive a safe concentration of daidzein in a body lotion von Najjar, Abdulkarim, Kühnl, Jochen, Lange, Daniela, Géniès, Camille, Jacques, Carine, Fabian, Eric, Zifle, Anne, Hewitt, Nicola J, Schepky, Andreas

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Incorporating integrated testing strategy (ITSv1) defined approach into read-across (RAx) in predicting skin sensitization potency: ITSv1-based RAx von Nakayama, Kanako, Zifle, Anne, Fritz, Sabrina, Fuchs, Anne, Sakaguchi, Hitoshi, Miyazawa, Masaaki

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Characterization of the in vitro penetration and first-pass metabolism of genistein and daidzein using human and pig skin explants and Phenion full-thickness skin models von Géniès, Camille, Jeanjean, Corinne, Najjar, Abdulkarim, Schepky, Andreas, Lange, Daniela, Kühnl, Jochen, Fabian, Eric, Zifle, Anne, Duplan, Hélène, Hewitt, NIcola J, Jacques, Carine

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Effect of vehicle on the in vitro penetration and metabolism of genistein and daidzein in ex vivo skin explants and the Phenion full-thickness skin model von Géniès, Camille, Jeanjean, Corinne, Najjar, Abdulkarim, Schepky, Andreas, Lange, Daniela, Kühnl, Jochen, Fabian, Eric, Zifle, Anne, Duplan, Helene, Hewitt, Nicola J, Jacques, Carine

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P-20. Challenges to Compromise in Safety Evaluation on Cosmetics with Threshold of Toxicological Concern and Read-Across von Taisuke Kawamoto, Anne Fuchs, Rolf Fautz, Osamu Morita, Anne Zifle, James Rathman, Aleksandra Mostrag, Chihae Yang, Masaaki Miyazawa

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