Enfuvirtide (T20)-Based Lipopeptide Is a Potent HIV-1 Cell Fusion Inhibitor: Implications for Viral Entry and Inhibition von Ding, Xiaohui, Zhang, Xiujuan, Chong, Huihui, Zhu, Yuanmei, Wei, Huamian, Wu, Xiyuan, He, Jinsheng, Wang, Xinquan, He, Yuxian

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Monotherapy with a low-dose lipopeptide HIV fusion inhibitor maintains long-term viral suppression in rhesus macaques von Chong, Huihui, Xue, Jing, Zhu, Yuanmei, Cong, Zhe, Chen, Ting, Wei, Qiang, Qin, Chuan, He, Yuxian

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SARS-CoV-2-derived fusion inhibitor lipopeptides exhibit highly potent and broad-spectrum activity against divergent human coronaviruses von Zhu, Yuanmei, Yu, Danwei, Hu, Yue, Wu, Tong, Chong, Huihui, He, Yuxian

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Resistance profile and mechanism of severe acute respiratory syndrome coronavirus-2 variants to LCB1 inhibitor targeting the spike receptor-binding motif von Wu, Tong, Zhu, Yuanmei, Liu, Nian, Hu, Yue, Chong, Huihui, He, Yuxian

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In Vitro Selection and Characterization of HIV-1 Variants with Increased Resistance to LP-40, Enfuvirtide-Based Lipopeptide Inhibitor von Hu, Yue, Yu, Wenjiang, Geng, Xiuzhu, Zhu, Yuanmei, Chong, Huihui, He, Yuxian

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Susceptibility and Resistance of SARS-CoV-2 Variants to LCB1 and Its Multivalent Derivatives von Jin, Hongliang, Gong, Yani, Cheng, Lin, Zhu, Yuanmei, Zhang, Zheng, He, Yuxian

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Cross-reactive neutralization of SARS-CoV-2 by serum antibodies from recovered SARS patients and immunized animals von Zhu, Yuanmei, Yu, Danwei, Han, Yang, Yan, Hongxia, Chong, Huihui, Ren, Lili, Wang, Jianwei, Li, Taisheng, He, Yuxian

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Generation of HIV-resistant cells with a single-domain antibody: implications for HIV-1 gene therapy von Jin, Hongliang, Tang, Xiaoran, Li, Li, Chen, Yue, Zhu, Yuanmei, Chong, Huihui, He, Yuxian

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Pan-coronavirus fusion inhibitors possess potent inhibitory activity against HIV-1, HIV-2, and simian immunodeficiency virus von Yu, Danwei, Zhu, Yuanmei, Yan, Hongxia, Wu, Tong, Chong, Huihui, He, Yuxian

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SARS-CoV-2 fusion-inhibitory lipopeptides maintain high potency against divergent variants of concern including Omicron von Zhu, Yuanmei, Dong, Xiaojing, Liu, Nian, Wu, Tong, Chong, Huihui, Lei, Xiaobo, Ren, Lili, Wang, Jianwei, He, Yuxian

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Cell membrane-anchored anti-HIV single-chain antibodies and bifunctional inhibitors targeting the gp41 fusion protein: new strategies for HIV gene therapy von Chen, Yue, Jin, Hongliang, Tang, Xiaoran, Li, Li, Geng, Xiuzhu, Zhu, Yuanmei, Chong, Huihui, He, Yuxian

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Design of a Bispecific HIV Entry Inhibitor Targeting the Cell Receptor CD4 and Viral Fusion Protein Gp41 von Yan, Hongxia, Wu, Tong, Chen, Yue, Jin, Hongliang, Li, Li, Zhu, Yuanmei, Chong, Huihui, He, Yuxian

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Design of Potent Membrane Fusion Inhibitors against SARS-CoV-2, an Emerging Coronavirus with High Fusogenic Activity von Zhu, Yuanmei, Yu, Danwei, Yan, Hongxia, Chong, Huihui, He, Yuxian

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Structure-based design and characterization of novel fusion-inhibitory lipopeptides against SARS-CoV-2 and emerging variants von Yu, Danwei, Zhu, Yuanmei, Jiao, Tao, Wu, Tong, Xiao, Xia, Qin, Bo, Chong, Huihui, Lei, Xiaobo, Ren, Lili, Cui, Sheng, Wang, Jianwei, He, Yuxian

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Conserved Residue Asn-145 in the C-Terminal Heptad Repeat Region of HIV-1 gp41 is Critical for Viral Fusion and Regulates the Antiviral Activity of Fusion Inhibitors von Geng, Xiuzhu, Liu, Zixuan, Yu, Danwei, Qin, Bo, Zhu, Yuanmei, Cui, Sheng, Chong, Huihui, He, Yuxian

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Structural and Functional Characterization of the Secondary Mutation N126K Selected by Various HIV-1 Fusion Inhibitors von Yu, Danwei, Su, Yang, Ding, Xiaohui, Zhu, Yuanmei, Qin, Bo, Chong, Huihui, Cui, Sheng, He, Yuxian

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Development of potent pan‐coronavirus fusion inhibitors with a new design strategy von Zhu, Yuanmei, Gao, Zhongcai, Feng, Xiaoli, Cheng, Lin, Liu, Nian, Liu, Chao, Han, Shaowei, Yang, Qiaojiang, Zou, Qingcui, Chong, Huihui, Zhang, Zheng, Li, Minghua, Song, Gengshen, He, Yuxian

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Structural Insights into the Mechanisms of Action of Short-Peptide HIV-1 Fusion Inhibitors Targeting the Gp41 Pocket von Zhang, Xiujuan, Zhu, Yuanmei, Hu, Hao, Zhang, Senyan, Wang, Pengfei, Chong, Huihui, He, Jinsheng, Wang, Xinquan, He, Yuxian

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Enterovirus 71 protease 2Apro and 3Cpro differentially inhibit the cellular endoplasmic reticulum-associated degradation (ERAD) pathway via distinct mechanisms, and enterovirus 71... von Wang, Tao, Wang, Bei, Huang, He, Zhang, Chongyang, Zhu, Yuanmei, Pei, Bin, Cheng, Chaofei, Sun, Lei, Wang, Jianwei, Jin, Qi, Zhao, Zhendong

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Characterization of novel HIV fusion-inhibitory lipopeptides with the M-T hook structure von Geng, Xiuzhu, Ding, Xiaohui, Zhu, Yuanmei, Chong, Huihui, He, Yuxian

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