Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing von Fei, Teng, Chen, Yiwen, Xiao, Tengfei, Li, Wei, Cato, Laura, Zhang, Peng, Cotter, Maura B., Bowden, Michaela, Lis, Rosina T., Zhao, Shuang G., Wu, Qiu, Feng, Felix Y., Loda, Massimo, He, Housheng Hansen, Liu, X. Shirley, Brown, Myles

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The lncRNA landscape of breast cancer reveals a role for DSCAM-AS1 in breast cancer progression von Niknafs, Yashar S., Han, Sumin, Ma, Teng, Speers, Corey, Zhang, Chao, Wilder-Romans, Kari, Iyer, Matthew K., Pitchiaya, Sethuramasundaram, Malik, Rohit, Hosono, Yasuyuki, Prensner, John R., Poliakov, Anton, Singhal, Udit, Xiao, Lanbo, Kregel, Steven, Siebenaler, Ronald F., Zhao, Shuang G., Uhl, Michael, Gawronski, Alexander, Hayes, Daniel F., Pierce, Lori J., Cao, Xuhong, Collins, Colin, Backofen, Rolf, Sahinalp, Cenk S., Rae, James M., Chinnaiyan, Arul M., Feng, Felix Y.

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Genomic Drivers of Poor Prognosis and Enzalutamide Resistance in Metastatic Castration-resistant Prostate Cancer von Chen, William S., Aggarwal, Rahul, Zhang, Li, Zhao, Shuang G., Thomas, George V., Beer, Tomasz M., Quigley, David A., Foye, Adam, Playdle, Denise, Huang, Jiaoti, Lloyd, Paul, Lu, Eric, Sun, Duanchen, Guan, Xiangnan, Rettig, Matthew, Gleave, Martin, Evans, Christopher P., Youngren, Jack, True, Lawrence, Lara, Primo, Kothari, Vishal, Xia, Zheng, Chi, Kim N., Reiter, Robert E., Maher, Christopher A., Feng, Felix Y., Small, Eric J., Alumkal, Joshi J.

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Maternal Embryonic Leucine Zipper Kinase (MELK) as a Novel Mediator and Biomarker of Radioresistance in Human Breast Cancer von Speers, Corey, Zhao, Shuang G, Kothari, Vishal, Santola, Alyssa, Liu, Meilan, Wilder-Romans, Kari, Evans, Joseph, Batra, Nidhi, Bartelink, Harry, Hayes, Daniel F, Lawrence, Theodore S, Brown, Powel H, Pierce, Lori J, Feng, Felix Y

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RB Loss Promotes Prostate Cancer Metastasis von Thangavel, Chellappagounder, Boopathi, Ettickan, Liu, Yi, Haber, Alex, Ertel, Adam, Bhardwaj, Anshul, Addya, Sankar, Williams, Noelle, Ciment, Stephen J, Cotzia, Paolo, Dean, Jeffry L, Snook, Adam, McNair, Chris, Price, Matt, Hernandez, James R, Zhao, Shuang G, Birbe, Ruth, McCarthy, James B, Turley, Eva A, Pienta, Kenneth J, Feng, Felix Y, Dicker, Adam P, Knudsen, Karen E, Den, Robert B

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Phase II Multicenter Study of Enzalutamide in Metastatic Castration-Resistant Prostate Cancer to Identify Mechanisms Driving Resistance von McKay, Rana R, Kwak, Lucia, Crowdis, Jett P, Sperger, Jamie M, Zhao, Shuang G, Xie, Wanling, Werner, Lillian, Lis, Rosina T, Zhang, Zhenwei, Wei, Xiao X, Lang, Joshua M, Van Allen, Eliezer M, Bhatt, Rupal S, Yu, Evan Y, Nelson, Peter S, Bubley, Glenn J, Montgomery, R Bruce, Taplin, Mary-Ellen

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Novel Transcriptomic Interactions Between Immune Content and Genomic Classifier Predict Lethal Outcomes in High-grade Prostate Cancer von Yamoah, Kosj, Awasthi, Shivanshu, Mahal, Brandon A., Zhao, Shuang G., Grass, G. Daniel, Berglund, Anders, Abraham-Miranda, Julieta, Gerke, Travis, Rounbehler, Robert J., Davicioni, Elai, Liu, Yang, Park, Jong, Cleveland, John L., Pow-Sang, Julio M., Fernandez, Daniel, Torres-Roca, Javier, Karnes, R. Jeffrey, Schaeffer, Edward, Freedland, Stephen J., Spratt, Daniel E., Den, Robert B., Rebbeck, Timothy R., Feng, Felix

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The Landscape of Prognostic Outlier Genes in High-Risk Prostate Cancer von Zhao, Shuang G, Evans, Joseph R, Kothari, Vishal, Sun, Grace, Larm, Ashley, Mondine, Victor, Schaeffer, Edward M, Ross, Ashley E, Klein, Eric A, Den, Robert B, Dicker, Adam P, Karnes, R Jeffrey, Erho, Nicholas, Nguyen, Paul L, Davicioni, Elai, Feng, Felix Y

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SV-HotSpot: detection and visualization of hotspots targeted by structural variants associated with gene expression von Eteleeb, Abdallah M., Quigley, David A., Zhao, Shuang G., Pham, Duy, Yang, Rendong, Dehm, Scott M., Luo, Jingqin, Feng, Felix Y., Dang, Ha X., Maher, Christopher A.

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Co-evolution of AR gene copy number and structural complexity in endocrine therapy resistant prostate cancer von Zivanovic, Andrej, Miller, Jeffrey T, Munro, Sarah A, Knutson, Todd P, Li, Yingming, Passow, Courtney N, Simonaitis, Pijus, Lynch, Molly, Oseth, LeAnn, Zhao, Shuang G, Feng, Felix Y, Wikström, Pernilla, Corey, Eva, Morrissey, Colm, Henzler, Christine, Raphael, Benjamin J, Dehm, Scott M

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Development and validation of a novel platform-independent metastasis signature in human breast cancer von Zhao, Shuang G, Shilkrut, Mark, Speers, Corey, Liu, Meilan, Wilder-Romans, Kari, Lawrence, Theodore S, Pierce, Lori J, Feng, Felix Y

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The Immune Landscape of Prostate Cancer and Nomination of PD-L2 as a Potential Therapeutic Target von Zhao, Shuang G, Lehrer, Jonathan, Chang, S Laura, Das, Rajdeep, Erho, Nicholas, Liu, Yang, Sjöström, Martin, Den, Robert B, Freedland, Stephen J, Klein, Eric A, Karnes, R Jeffrey, Schaeffer, Edward M, Xu, Melody, Speers, Corey, Nguyen, Paul L, Ross, Ashley E, Chan, June M, Cooperberg, Matthew R, Carroll, Peter R, Davicioni, Elai, Fong, Lawrence, Spratt, Daniel E, Feng, Felix Y

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A phenocopy signature of TP53 loss predicts response to chemotherapy von Bakhtiar, Hamza, Sharifi, Marina N., Helzer, Kyle T., Shi, Yue, Bootsma, Matthew L., Shang, Tianfu A., Chrostek, Matthew R., Berg, Tracy J., Carson Callahan, S., Carreno, Viridiana, Blitzer, Grace C., West, Malinda T., O’Regan, Ruth M., Wisinski, Kari B., Sjöström, Martin, Zhao, Shuang G.

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Clinicogenomic Radiotherapy Classifier Predicting the Need for Intensified Locoregional Treatment After Breast-Conserving Surgery for Early-Stage Breast Cancer von Sjöström, Martin, Chang, S Laura, Fishbane, Nick, Davicioni, Elai, Zhao, Shuang G, Hartman, Linda, Holmberg, Erik, Feng, Felix Y, Speers, Corey W, Pierce, Lori J, Malmström, Per, Fernö, Mårten, Karlsson, Per

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Androgen receptor as a mediator and biomarker of radioresistance in triple-negative breast cancer von Speers, Corey, Zhao, Shuang G., Chandler, Ben, Liu, Meilan, Wilder-Romans, Kari, Olsen, Eric, Nyati, Shyam, Ritter, Cassandra, Alluri, Prasanna G., Kothari, Vishal, Hayes, Daniel F., Lawrence, Theodore S., Spratt, Daniel E., Wahl, Daniel R., Pierce, Lori J., Feng, Felix Y.

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Individual Patient-Level Meta-Analysis of the Performance of the Decipher Genomic Classifier in High-Risk Men After Prostatectomy to Predict Development of Metastatic Disease von Spratt, Daniel E, Yousefi, Kasra, Deheshi, Samineh, Ross, Ashley E, Den, Robert B, Schaeffer, Edward M, Trock, Bruce J, Zhang, Jingbin, Glass, Andrew G, Dicker, Adam P, Abdollah, Firas, Zhao, Shuang G, Lam, Lucia L C, du Plessis, Marguerite, Choeurng, Voleak, Haddad, Zaid, Buerki, Christine, Davicioni, Elai, Weinmann, Sheila, Freedland, Stephen J, Klein, Eric A, Karnes, R Jeffrey, Feng, Felix Y

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Purine metabolism regulates DNA repair and therapy resistance in glioblastoma von Zhou, Weihua, Yao, Yangyang, Scott, Andrew J., Wilder-Romans, Kari, Dresser, Joseph J., Werner, Christian K., Sun, Hanshi, Pratt, Drew, Sajjakulnukit, Peter, Zhao, Shuang G., Davis, Mary, Nelson, Barbara S., Halbrook, Christopher J., Zhang, Li, Gatto, Francesco, Umemura, Yoshie, Walker, Angela K., Kachman, Maureen, Sarkaria, Jann N., Xiong, Jianping, Morgan, Meredith A., Rehemtualla, Alnawaz, Castro, Maria G., Lowenstein, Pedro, Chandrasekaran, Sriram, Lawrence, Theodore S., Lyssiotis, Costas A., Wahl, Daniel R.

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A Systematic Review of the Evidence for the Decipher Genomic Classifier in Prostate Cancer von Jairath, Neil K., Dal Pra, Alan, Vince, Randy, Dess, Robert T., Jackson, William C., Tosoian, Jeffrey J., McBride, Sean M., Zhao, Shuang G., Berlin, Alejandro, Mahal, Brandon A., Kishan, Amar U., Den, Robert B., Freedland, Stephen J., Salami, Simpa S., Kaffenberger, Samuel D., Pollack, Alan, Tran, Phuoc, Mehra, Rohit, Morgan, Todd M., Weiner, Adam B., Mohamad, Osama, Carroll, Peter R., Cooperberg, Matthew R., Karnes, R. Jeffrey, Nguyen, Paul L., Michalski, Jeff M., Tward, Jonathan D., Feng, Felix Y., Schaeffer, Edward M., Spratt, Daniel E.

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Identification of phenocopies improves prediction of targeted therapy response over DNA mutations alone von Bakhtiar, Hamza, Helzer, Kyle T., Park, Yeonhee, Chen, Yi, Rydzewski, Nicholas R., Bootsma, Matthew L., Shi, Yue, Harari, Paul M., Sharifi, Marina, Sjöström, Martin, Lang, Joshua M., Yu, Menggang, Zhao, Shuang G.

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A platform-independent AI tumor lineage and site (ATLAS) classifier von Rydzewski, Nicholas R., Shi, Yue, Li, Chenxuan, Chrostek, Matthew R., Bakhtiar, Hamza, Helzer, Kyle T., Bootsma, Matthew L., Berg, Tracy J., Harari, Paul M., Floberg, John M., Blitzer, Grace C., Kosoff, David, Taylor, Amy K., Sharifi, Marina N., Yu, Menggang, Lang, Joshua M., Patel, Krishnan R., Citrin, Deborah E., Sundling, Kaitlin E., Zhao, Shuang G.

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