Chromothripsis as an on-target consequence of CRISPR–Cas9 genome editing von Leibowitz, Mitchell L., Papathanasiou, Stamatis, Doerfler, Phillip A., Blaine, Logan J., Sun, Lili, Yao, Yu, Zhang, Cheng-Zhong, Weiss, Mitchell J., Pellman, David

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Breaching Self-Tolerance to Alu Duplex RNA Underlies MDA5-Mediated Inflammation von Ahmad, Sadeem, Mu, Xin, Yang, Fei, Greenwald, Emily, Park, Ji Woo, Jacob, Etai, Zhang, Cheng-Zhong, Hur, Sun

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Whole chromosome loss and genomic instability in mouse embryos after CRISPR-Cas9 genome editing von Papathanasiou, Stamatis, Markoulaki, Styliani, Blaine, Logan J., Leibowitz, Mitchell L., Zhang, Cheng-Zhong, Jaenisch, Rudolf, Pellman, David

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Chromothripsis from DNA damage in micronuclei von Zhang, Cheng-Zhong, Spektor, Alexander, Cornils, Hauke, Francis, Joshua M., Jackson, Emily K., Liu, Shiwei, Meyerson, Matthew, Pellman, David

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Mechanisms generating cancer genome complexity from a single cell division error von Umbreit, Neil T., Zhang, Cheng-Zhong, Lynch, Luke D., Blaine, Logan J., Cheng, Anna M., Tourdot, Richard, Sun, Lili, Almubarak, Hannah F., Judge, Kim, Mitchell, Thomas J., Spektor, Alexander, Pellman, David

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Mechanoenzymatic Cleavage of the Ultralarge Vascular Protein Von Willebrand Factor von Zhang, Xiaohui, Halvorsen, Kenneth, Zhang, Cheng-Zhong, Wong, Wesley P., Springer, Timothy A.

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Chromothripsis: A New Mechanism for Rapid Karyotype Evolution von Leibowitz, Mitchell L, Zhang, Cheng-Zhong, Pellman, David

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Chromothripsis and beyond: rapid genome evolution from complex chromosomal rearrangements von Zhang, Cheng-Zhong, Leibowitz, Mitchell L, Pellman, David

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Examining the cooperation between extrachromosomal DNA circles von Zhang, Jiahui, Zhang, Cheng-Zhong

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Pan-cancer patterns of somatic copy number alteration von Zack, Travis I, Schumacher, Steven E, Carter, Scott L, Cherniack, Andrew D, Saksena, Gordon, Tabak, Barbara, Lawrence, Michael S, Zhang, Cheng-Zhong, Wala, Jeremiah, Mermel, Craig H, Sougnez, Carrie, Gabriel, Stacey B, Hernandez, Bryan, Shen, Hui, Laird, Peter W, Getz, Gad, Meyerson, Matthew, Beroukhim, Rameen

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SvABA: genome-wide detection of structural variants and indels by local assembly von Wala, Jeremiah A, Bandopadhayay, Pratiti, Greenwald, Noah F, O'Rourke, Ryan, Sharpe, Ted, Stewart, Chip, Schumacher, Steve, Li, Yilong, Weischenfeldt, Joachim, Yao, Xiaotong, Nusbaum, Chad, Campbell, Peter, Getz, Gad, Meyerson, Matthew, Zhang, Cheng-Zhong, Imielinski, Marcin, Beroukhim, Rameen

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A mechanically stabilized receptor-ligand flex-bond important in the vasculature von Springer, Timothy A, Kim, Jongseong, Zhang, Cheng-Zhong, Zhang, Xiaohui

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Determination of complete chromosomal haplotypes by bulk DNA sequencing von Tourdot, Richard W., Brunette, Gregory J., Pinto, Ricardo A., Zhang, Cheng-Zhong

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Genomic Copy Number Dictates a Gene-Independent Cell Response to CRISPR/Cas9 Targeting von Aguirre, Andrew J, Meyers, Robin M, Weir, Barbara A, Vazquez, Francisca, Zhang, Cheng-Zhong, Ben-David, Uri, Cook, April, Ha, Gavin, Harrington, William F, Doshi, Mihir B, Kost-Alimova, Maria, Gill, Stanley, Xu, Han, Ali, Levi D, Jiang, Guozhi, Pantel, Sasha, Lee, Yenarae, Goodale, Amy, Cherniack, Andrew D, Oh, Coyin, Kryukov, Gregory, Cowley, Glenn S, Garraway, Levi A, Stegmaier, Kimberly, Roberts, Charles W, Golub, Todd R, Meyerson, Matthew, Root, David E, Tsherniak, Aviad, Hahn, William C

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Targeted and genome-wide sequencing reveal single nucleotide variations impacting specificity of Cas9 in human stem cells von Yang, Luhan, Grishin, Dennis, Wang, Gang, Aach, John, Zhang, Cheng-Zhong, Chari, Raj, Homsy, Jason, Cai, Xuyu, Zhao, Yue, Fan, Jian-Bing, Seidman, Christine, Seidman, Jonathan, Pu, William, Church, George

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EGFR variant heterogeneity in glioblastoma resolved through single-nucleus sequencing von Francis, Joshua M, Zhang, Cheng-Zhong, Maire, Cecile L, Jung, Joonil, Manzo, Veronica E, Adalsteinsson, Viktor A, Homer, Heather, Haidar, Sam, Blumenstiel, Brendan, Pedamallu, Chandra Sekhar, Ligon, Azra H, Love, J Christopher, Meyerson, Matthew, Ligon, Keith L

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Structural specializations of A2, a force-sensing domain in the ultralarge vascular protein von Willebrand factor von Zhang, Qing, Zhou, Yan-Feng, Zhang, Cheng-Zhong, Zhang, Xiaohui, Lu, Chafen, Springer, Timothy A

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Exome sequencing of lymphomas from three dog breeds reveals somatic mutation patterns reflecting genetic background von Elvers, Ingegerd, Turner-Maier, Jason, Swofford, Ross, Koltookian, Michele, Johnson, Jeremy, Stewart, Chip, Zhang, Cheng-Zhong, Schumacher, Steven E, Beroukhim, Rameen, Rosenberg, Mara, Thomas, Rachael, Mauceli, Evan, Getz, Gad, Palma, Federica Di, Modiano, Jaime F, Breen, Matthew, Lindblad-Toh, Kerstin, Alföldi, Jessica

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Genomic signatures of past and present chromosomal instability in Barrett’s esophagus and early esophageal adenocarcinoma von Bao, Chunyang, Tourdot, Richard W., Brunette, Gregory J., Stewart, Chip, Sun, Lili, Baba, Hideo, Watanabe, Masayuki, Agoston, Agoston T., Jajoo, Kunal, Davison, Jon M., Nason, Katie S., Getz, Gad, Wang, Kenneth K., Imamura, Yu, Odze, Robert, Bass, Adam J., Stachler, Matthew D., Zhang, Cheng-Zhong

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Calibrating genomic and allelic coverage bias in single-cell sequencing von Zhang, Cheng-Zhong, Adalsteinsson, Viktor A., Francis, Joshua, Cornils, Hauke, Jung, Joonil, Maire, Cecile, Ligon, Keith L., Meyerson, Matthew, Love, J. Christopher

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