Herpes simplex virus encephalitis of childhood: inborn errors of central nervous system cell-intrinsic immunity von Zhang, Shen-Ying

Volltext

Human TBK1: A Gatekeeper of Neuroinflammation von Ahmad, Liyana, Zhang, Shen-Ying, Casanova, Jean-Laurent, Sancho-Shimizu, Vanessa

Volltext

Human autoantibodies neutralizing type I IFNs: From 1981 to 2023 von Bastard, Paul, Gervais, Adrian, Le Voyer, Tom, Philippot, Quentin, Cobat, Aurélie, Rosain, Jérémie, Jouanguy, Emmanuelle, Abel, Laurent, Zhang, Shen‐Ying, Zhang, Qian, Puel, Anne, Casanova, Jean‐Laurent

Volltext

Autosomal Recessive Cardiomyopathy Presenting as Acute Myocarditis von Belkaya, Serkan, PhD, Kontorovich, Amy R., MD, PhD, Byun, Minji, PhD, Mulero-Navarro, Sonia, PhD, Bajolle, Fanny, MD, PhD, Cobat, Aurelie, MD, PhD, Josowitz, Rebecca, MD, PhD, Itan, Yuval, PhD, Quint, Raphaelle, MSc, Lorenzo, Lazaro, MSc, Boucherit, Soraya, MD, Stoven, Cecile, MD, Di Filippo, Sylvie, MD, PhD, Abel, Laurent, MD, PhD, Zhang, Shen-Ying, MD, PhD, Bonnet, Damien, MD, PhD, Gelb, Bruce D., MD, Casanova, Jean-Laurent, MD, PhD

Volltext

SARS-CoV-2 induces human plasmacytoid predendritic cell diversification via UNC93B and IRAK4 von Onodi, Fanny, Bonnet-Madin, Lucie, Meertens, Laurent, Karpf, Lea, Poirot, Justine, Zhang, Shen-Ying, Picard, Capucine, Puel, Anne, Jouanguy, Emmanuelle, Zhang, Qian, Le Goff, Jerome, Molina, Jean-Michel, Delaugerre, Constance, Casanova, Jean-Laurent, Amara, Ali, Soumelis, Vassili

Volltext

Life-Threatening COVID-19: Defective Interferons Unleash Excessive Inflammation von Zhang, Qian, Bastard, Paul, Bolze, Alexandre, Jouanguy, Emmanuelle, Zhang, Shen-Ying, Cobat, Aurélie, Notarangelo, Luigi D., Su, Helen C., Abel, Laurent, Casanova, Jean-Laurent

Volltext

Human inborn errors of immunity to infection affecting cells other than leukocytes: from the immune system to the whole organism von Zhang, Shen-Ying, Jouanguy, Emmanuelle, Zhang, Qian, Abel, Laurent, Puel, Anne, Casanova, Jean-Laurent

Volltext

Inborn errors underlying herpes simplex encephalitis: From TLR3 to IRF3 von Zhang, Shen-Ying, Casanova, Jean-Laurent

Volltext

The mutation significance cutoff: gene-level thresholds for variant predictions von Itan, Yuval, Shang, Lei, Boisson, Bertrand, Ciancanelli, Michael J, Markle, Janet G, Martinez-Barricarte, Ruben, Scott, Eric, Shah, Ishaan, Stenson, Peter D, Gleeson, Joseph, Cooper, David N, Quintana-Murci, Lluis, Zhang, Shen-Ying, Abel, Laurent, Casanova, Jean-Laurent

Volltext

Host genetics of severe influenza: from mouse Mx1 to human IRF7 von Ciancanelli, Michael J, Abel, Laurent, Zhang, Shen-Ying, Casanova, Jean-Laurent

Volltext

A novel kindred with inherited STAT2 deficiency and severe viral illness von Moens, Leen, PhD, Van Eyck, Lien, MSc, MD, Jochmans, Dirk, PhD, Mitera, Tania, BSc, Frans, Glynis, MPharm, Bossuyt, Xavier, MD, PhD, Matthys, Patrick, PhD, Neyts, Johan, PhD, Ciancanelli, Michael, PhD, Zhang, Shen-Ying, MD, PhD, Gijsbers, Rik, PhD, Casanova, Jean-Laurent, MD, PhD, Boisson-Dupuis, Stephanie, PhD, Meyts, Isabelle, MD, PhD, Liston, Adrian, PhD

Volltext

Human inborn errors of immunity to herpes viruses von Jouanguy, Emmanuelle, Béziat, Vivien, Mogensen, Trine H, Casanova, Jean-Laurent, Tangye, Stuart G, Zhang, Shen-Ying

Volltext

Severe COVID-19 in the young and healthy: monogenic inborn errors of immunity? von Zhang, Shen-Ying, Zhang, Qian, Casanova, Jean-Laurent, Su, Helen C.

Volltext

IFN-α2a Therapy in Two Patients with Inborn Errors of TLR3 and IRF3 Infected with SARS-CoV-2 von Lévy, Romain, Bastard, Paul, Lanternier, Fanny, Lecuit, Marc, Zhang, Shen-Ying, Casanova, Jean-Laurent

Volltext

Parsing the Interferon Transcriptional Network and Its Disease Associations von Mostafavi, Sara, Yoshida, Hideyuki, Moodley, Devapregasan, LeBoité, Hugo, Rothamel, Katherine, Raj, Towfique, Ye, Chun Jimmie, Chevrier, Nicolas, Zhang, Shen-Ying, Feng, Ting, Lee, Mark, Casanova, Jean-Laurent, Clark, James D., Hegen, Martin, Telliez, Jean-Baptiste, Hacohen, Nir, De Jager, Philip L., Regev, Aviv, Mathis, Diane, Benoist, Christophe

Volltext

Human SNORA31 variations impair cortical neuron-intrinsic immunity to HSV-1 and underlie herpes simplex encephalitis von Lafaille, Fabien G., Harschnitz, Oliver, Lee, Yoon Seung, Zhang, Peng, Hasek, Mary L., Kerner, Gaspard, Itan, Yuval, Ewaleifoh, Osefame, Rapaport, Franck, Carlile, Thomas M., Carter-Timofte, Madalina E., Paquet, Dominik, Dobbs, Kerry, Zimmer, Bastian, Gao, Daxing, Rojas-Duran, Maria F., Kwart, Dylan, Rattina, Vimel, Ciancanelli, Michael J., McAlpine, Jessica L., Lorenzo, Lazaro, Boucherit, Soraya, Rozenberg, Flore, Halwani, Rabih, Henry, Benoit, Amenzoui, Naima, Alsum, Zobaida, Marques, Laura, Church, Joseph A., Al-Muhsen, Saleh, Tardieu, Marc, Bousfiha, Ahmed Aziz, Paludan, Søren R., Mogensen, Trine Hyrup, Quintana-Murci, Lluis, Tessier-Lavigne, Marc, Smith, Gregory A., Notarangelo, Luigi D., Studer, Lorenz, Gilbert, Wendy, Abel, Laurent, Casanova, Jean-Laurent, Zhang, Shen-Ying

Volltext

PopViz: a webserver for visualizing minor allele frequencies and damage prediction scores of human genetic variations von Zhang, Peng, Bigio, Benedetta, Rapaport, Franck, Zhang, Shen-Ying, Casanova, Jean-Laurent, Abel, Laurent, Boisson, Bertrand, Itan, Yuval

Volltext

Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells von Lafaille, Fabien G., Pessach, Itai M., Zhang, Shen-Ying, Ciancanelli, Michael J., Herman, Melina, Abhyankar, Avinash, Ying, Shui-Wang, Keros, Sotirios, Goldstein, Peter A., Mostoslavsky, Gustavo, Ordovas-Montanes, Jose, Jouanguy, Emmanuelle, Plancoulaine, Sabine, Tu, Edmund, Elkabetz, Yechiel, Al-Muhsen, Saleh, Tardieu, Marc, Schlaeger, Thorsten M., Daley, George Q., Abel, Laurent, Casanova, Jean-Laurent, Studer, Lorenz, Notarangelo, Luigi D.

Volltext

The human gene damage index as a gene-level approach to prioritizing exome variants von Itan, Yuval, Shang, Lei, Boisson, Bertrand, Patin, Etienne, Bolze, Alexandre, Moncada-Vélez, Marcela, Scott, Eric, Ciancanelli, Michael J., Lafaille, Fabien G., Markle, Janet G., Martinez-Barricarte, Ruben, de Jong, Sarah Jill, Kong, Xiao-Fei, Nitschke, Patrick, Belkadi, Aziz, Bustamante, Jacinta, Puel, Anne, Boisson-Dupuis, Stéphanie, Stenson, Peter D., Gleeson, Joseph G., Cooper, David N., Quintana-Murci, Lluis, Claverie, Jean-Michel, Zhang, Shen-Ying, Abel, Laurent, Casanova, Jean-Laurent

Volltext

Negative selection on human genes underlying inborn errors depends on disease outcome and both the mode and mechanism of inheritance von Rapaport, Franck, Boisson, Bertrand, Gregor, Anne, Béziat, Vivien, Boisson-Dupuis, Stéphanie, Bustamante, Jacinta, Jouanguy, Emmanuelle, Puel, Anne, Rosain, Jérémie, Zhang, Qian, Zhang, Shen-Ying, Gleeson, Joseph G., Quintana-Murci, Lluis, Casanova, Jean-Laurent, Abel, Laurent, Patin, Etienne

Volltext