M3814: A novel investigational DNA-PK inhibitor to target DNA double strand break repair von Zenke, F.T.

Volltext

Nitric Oxide Destroys Zinc-Sulfur Clusters Inducing Zinc Release from Metallothionein and Inhibition of the Zinc Finger-Type Yeast Transcription Activator LAC9 von Kroncke, K.D., Fehsel, K., Schmidt, T., Zenke, F.T., Dasting, I., Wesener, J.R., Bettermann, H., Breunig, K.D., Kolbbachofen, V.

Volltext

Regulated phosphorylation of the Gal4p inhibitor Gal80p of Kluyveromyces lactis revealed by mutational analysis von Zenke, F.T, Kapp, L, Breunig, K.D

Volltext

Activation of Gal4p by Galactose-Dependent Interaction of Galactokinase and Gal80p von Zenke, F. T., Engels, R., Vollenbroich, V., Meyer, J., Hollenberg, C. P., Breunig, K. D.

Volltext

KIT D816V Mast Cells Derived from Induced Pluripotent Stem Cells Recapitulate Systemic Mastocytosis Transcriptional Profile von de Toledo, Marcelo A S, Fu, Xuhuang, Maié, Tiago, Buhl, Eva M, Götz, Katrin, Schmitz, Susanne, Kaiser, Anne, Boor, Peter, Braunschweig, Till, Chatain, Nicolas, Costa, Ivan G, Brümmendorf, Tim H, Koschmieder, Steffen, Zenke, Martin

Volltext

Two Distinct Types of Langerhans Cells Populate the Skin during Steady State and Inflammation von Seré, Kristin, Baek, Jea-Hyun, Ober-Blöbaum, Julia, Müller-Newen, Gerhard, Tacke, Frank, Yokota, Yoshifumi, Zenke, Martin, Hieronymus, Thomas

Volltext

The Concordant Disruption of B7/CD28 Immune Regulators Predicts the Prognosis of Oral Carcinomas von Chang, Shi-Rou, Chou, Chung-Hsien, Liu, Chung-Ji, Lin, Yu-Cheng, Tu, Hsi-Feng, Chang, Kuo-Wei, Lin, Shu-Chun

Volltext

Tumor Treating Fields (TTFields) Hinder Cancer Cell Motility through Regulation of Microtubule and Actin Dynamics von Voloshin, Tali, Schneiderman, Rosa Sara, Volodin, Alexandra, Shamir, Reuben Ruby, Kaynan, Noa, Zeevi, Einav, Koren, Lilach, Klein-Goldberg, Anat, Paz, Rom, Giladi, Moshe, Bomzon, Zeev, Weinberg, Uri, Palti, Yoram

Volltext

DNA-Dependent Protein Kinase Inhibitor Peposertib Potentiates the Cytotoxicity of Topoisomerase II Inhibitors in Synovial Sarcoma Models von Revia, Steffie, Budzinska, Magdalena A, Bogatyrova, Olga, Neumann, Felix, Zimmermann, Astrid, Amendt, Christiane, Albers, Joachim

Volltext

Peposertib, a DNA-PK Inhibitor, Enhances the Anti-Tumor Efficacy of Topoisomerase II Inhibitors in Triple-Negative Breast Cancer Models von Revia, Steffie, Neumann, Felix, Jabs, Julia, Orio, Florian, Sirrenberg, Christian, Zimmermann, Astrid, Amendt, Christiane, Albers, Joachim

Volltext

Triple-Negative Breast Cancer and Emerging Therapeutic Strategies: ATR and CHK1/2 as Promising Targets von Sofianidi, Amalia, Dumbrava, Ecaterina E, Syrigos, Konstantinos N, Nasrazadani, Azadeh

Volltext

Transcriptional control of the GAL/MEL regulon of yeast Saccharomyces cerevisiae: mechanism of galactose‐mediated signal transduction von Bhat, P. Jayadeva, Murthy, T. V. S.

Volltext

Beyond DNA Repair: DNA-PKcs in Tumor Metastasis, Metabolism and Immunity von Yang, Haitang, Yao, Feng, Marti, Thomas M, Schmid, Ralph A, Peng, Ren-Wang

Volltext

Reducing GEF-H1 Expression Inhibits Renal Cyst Formation, Inflammation, and Fibrosis via RhoA Signaling in Nephronophthisis von Hu, Qiulei, Lai, Jiayong, Chen, Huamu, Cai, Yong, Yue, Zhihui, Lin, Hongrong, Sun, Liangzhong

Volltext

Identification and Validation of New DNA-PKcs Inhibitors through High-Throughput Virtual Screening and Experimental Verification von Dai, Liujiang, Yu, Pengfei, Fan, Hongjie, Xia, Wei, Zhao, Yaopeng, Zhang, Pengfei, Zhang, John Z H, Zhang, Haiping, Chen, Yang

Volltext

The role of metallothionein in oxidative stress von Ruttkay-Nedecky, Branislav, Nejdl, Lukas, Gumulec, Jaromir, Zitka, Ondrej, Masarik, Michal, Eckschlager, Tomas, Stiborova, Marie, Adam, Vojtech, Kizek, Rene

Volltext

Altered Cortical Synaptic Morphology and Impaired Memory Consolidation in Forebrain- Specific Dominant-Negative PAK Transgenic Mice von Hayashi, Mansuo L, Choi, Se-Young, Rao, B.S.Shankaranarayana, Jung, Hae-Yoon, Lee, Hey-Kyoung, Zhang, Dawei, Chattarji, Sumantra, Kirkwood, Alfredo, Tonegawa, Susumu

Volltext

Disruption of RNA Splicing Increases Vulnerability of Cells to DNA-PK Inhibitors von Kovina, Anastasia P, Luzhin, Artem V, Tatarskiy, Victor V, Deriglazov, Dmitry A, Petrova, Natalia V, Petrova, Nadezhda V, Kondratyeva, Liya G, Kantidze, Omar L, Razin, Sergey V, Velichko, Artem K

Volltext

Ephrin-B3 reverse signaling through Grb4 and cytoskeletal regulators mediates axon pruning von Henkemeyer, Mark, Xu, Nan-Jie

Volltext

Brain-Inspired Architecture for Spiking Neural Networks von Tang, Fengzhen, Zhang, Junhuai, Zhang, Chi, Liu, Lianqing

Volltext