A Novel System for Functional Determination of Variants of Uncertain Significance using Deep Convolutional Neural Networks von Zimmerman, Lior, Zelichov, Ori, Aizenmann, Arie, Barbash, Zohar, Vidne, Michael, Tarcic, Gabi

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Novel Biomarker Proteins in Chronic Lymphocytic Leukemia: Impact on Diagnosis, Prognosis and Treatment von Admoni-Elisha, Lee, Nakdimon, Itay, Shteinfer, Anna, Prezma, Tal, Arif, Tasleem, Arbel, Nir, Melkov, Anna, Zelichov, Ori, Levi, Itai, Shoshan-Barmatz, Varda

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Identification of osimertinib-resistant EGFR L792 mutations by cfDNA sequencing: oncogenic activity assessment and prevalence in large cfDNA cohort von Fairclough, Stephen R, Kiedrowski, Lesli A, Lin, Jessica J, Zelichov, Ori, Tarcic, Gabi, Stinchcombe, Thomas E, Odegaard, Justin I, Lanman, Richard B, Shaw, Alice T, Nagy, Rebecca J

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Functional measurement of mitogen-activated protein kinase pathway activation predicts responsiveness of RAS-mutant cancers to MEK inhibitors von Kato, Shumei, Porter, Robert, Okamura, Ryosuke, Lee, Suzanna, Zelichov, Ori, Tarcic, Gabi, Vidne, Michael, Kurzrock, Razelle

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Comparing genomic landscape of early stage, treatment naïve and late stage, drug resistant EGFR-mutant lung adenocarcinomas von Nahar, Rahul, Lee, Yin Yeng, Khng, Alexis J., Zhang, Tong, Takano, Angela, Liu, Xingliang, Alvarez, Jacob J.S., Zelichov, Ori, Ella, Ezra, Barbash, Zohar, Lim, Chong Hee, Koh, Tina P.T., Aung, Zaw Win, Lim, Tony Kiat Hon, Toh, Chee Keong, Lim, Wan-Teck, Lim, Bing, Tam, Wai Leong, Tan, Eng-Huat, Zhai, Weiwei, Tan, Daniel S.W., Hillmer, Axel M.

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Predicting response to naratuximab emtansine, an anti-CD37 antibody-drug conjugate (ADC), in combination with rituximab in diffuse large B-cell lymphoma (DLBCL), by analyzing the s... von Pokorska-Bocci, Anna, Micallef, Sandrine, Dymkowska, Mariola, Gabay, Yuval, Gluskin, Roman, Laniado, Avi, Dicker Sagy, Efrat, Bart, Amit, Dicker, Tomer, Rotbein, Ifat, Achtenberg, Albert, Zelichov, Ori

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Mapping the activation landscape of the MAPK\ERK pathway for variants of unknown significance (VUS) using convolutional neural networks (CNN) von Tarcic, Gabi, Zimmerman, Lior, Aizenman, Arie, Barbash, Zohar, Zelichov, Ori, Vidne, Michael

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A functional measurement of MAPK pathway activation to predict response to MEK inhibitors in RAS-mutated patients von Kato, Shumei, Porter, Robert, Okamura, Ryosuke, Zelichov, Ori, Tarcic, Gabi, Vidne, Michael, Kurzrock, Razelle

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Predicting response to pembrolizumab in non-small cell lung cancer, by analyzing the spatial arrangement of tumor infiltrating lymphocytes using deep learning von Ofek, Efrat, Bar, Jair, Zer, Alona, Urban, Damien, Mayer, Chen, Sade, Chen, Zelichov, Ori, Groisman, Alon, Laniado, Avi, Gabay, Yuval, Polychenko, Willy, Gluskin, Roman, Achtenberg, Albert, Feinmesser, Meora, Barshack, Iris

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Clinical and Functional Characterization of Atypical KRAS/NRAS Mutations in Metastatic Colorectal Cancer von Loree, Jonathan M., Wang, Yucai, Syed, Muddassir A., Sorokin, Alexey, Coker, Oluwadara, Xiu, Joanne, Weinberg, Benjamin A., Vanderwalde, Ari M., Tesfaye, Anteneh, Raymond, Victoria M., Miron, Benjamin, Tarcic, Gabi, Zelichov, Ori, Broaddus, Russell R., Ng, Patrick Kwok Shing, Jeong, Kang Jin, Tsang, Yiu Huen, Mills, Gordon B., Overman, Michael J., Grothey, Axel, Marshall, John L., Kopetz, Scott

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Clinical and Functional Characterization of Atypical KRAS/NRAS Mutations in Metastatic Colorectal Cancer von Loree, Jonathan M., Wang, Yucai, Syed, Muddassir A., Sorokin, Alexey V., Coker, Oluwadara, Xiu, Joanne, Weinberg, Benjamin A., Vanderwalde, Ari M., Tesfaye, Anteneh, Raymond, Victoria M., Miron, Benjamin, Tarcic, Gabi, Zelichov, Ori, Broaddus, Russell R., Ng, Patrick Kwok Shing, Jeong, Kang Jin, Tsang, Yiu Huen, Mills, Gordon B., Overman, Michael J., Grothey, Axel, Marshall, John L., Kopetz, Scott

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Abstract 4316: Identification of tertiary lymphoid structures from H&E slides using deep learning analysis of nuclear morphology is associated with favorable survival in colorectal... von Arbiv, Becky, Dankovich, Tal, Dagan, Sun, Shachaf, Yuval, Dicker, Tomer, Elran, Ron, Laniado, Avi, Bart, Amit, Zelichov, Ori, Markovits, Ettai

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In vitro functional analysis of HER2 variants in lung cancers to evaluate their oncogenic activity and predict response to HER2-targeted therapy von Liu, Dazhi, Offin, Michael David, Olah, Zachary T., Tarcic, Gabi, Zelichov, Ori, Vidne, Michael, Drilon, Alexander E., Arcila, Maria E., Li, Bob T.

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The predictive potential of the spatial signature of lymphocytes in breast cancer patients von Balint-Lahat, Nora, Mayer, Chen, Ben-Baruch, Noa, Yosepovich, Ady, Sacks, Kira, Ish-Shalom, Shahar, Molchanov, Yossef, Dadiani, Maya, Morzaev-Sulzbach, Dana, Gal-Yam, Einav Nili, Achtenberg, Albert, Gabay, Yuval, Gluskin, Roman, Griosman, Alon, Shachaf, Yuval, Luchtenstein, Amir, Zelichov, Ori, Alexander, Kathrina, Lazar, Alexander J., Barshack, Iris

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