Synthetic lethality between androgen receptor signalling and the PARP pathway in prostate cancer von Asim, Mohammad, Tarish, Firas, Zecchini, Heather I., Sanjiv, Kumar, Gelali, Eleni, Massie, Charles E., Baridi, Ajoeb, Warren, Anne Y., Zhao, Wanfeng, Ogris, Christoph, McDuffus, Leigh-Anne, Mascalchi, Patrice, Shaw, Greg, Dev, Harveer, Wadhwa, Karan, Wijnhoven, Paul, Forment, Josep V., Lyons, Scott R., Lynch, Andy G., O’Neill, Cormac, Zecchini, Vincent R., Rennie, Paul S., Baniahmad, Aria, Tavaré, Simon, Mills, Ian G., Galanty, Yaron, Crosetto, Nicola, Schultz, Niklas, Neal, David, Helleday, Thomas

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Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition von Sciacovelli, M, Goncalves, E, Johnson, TI, Zecchini, VR, da Costa, ASH, Gaude, E, Drubbel, AV, Theobald, SJ, Abbo, SR, Tran, MGB, Rajeeve, V, Cardaci, S, Foster, S, Yun, H, Cutillas, P, Warren, A, Gnanapragasam, V, Gottlieb, E, Franze, K, Huntly, B, Maher, ER, Maxwell, PH, Saez-Rodriguez, J, Frezza, C

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The Parkinson's disease protein LRRK2 impairs proteasome substrate clearance without affecting proteasome catalytic activity von Lichtenberg, M, Mansilla, A, Zecchini, VR, Fleming, A, Rubinsztein, DC

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