Evaluation of targeted therapies in advanced breast cancer: the need for large-scale molecular screening and transformative clinical trial designs von Fadoukhair, Z, Zardavas, D, Chad, M A, Goulioti, T, Aftimos, P, Piccart, M

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The AURORA initiative for metastatic breast cancer von Zardavas, D, Maetens, M, Irrthum, A, Goulioti, T, Engelen, K, Fumagalli, D, Salgado, R, Aftimos, P, Saini, K S, Sotiriou, C, Campbell, P, Dinh, P, von Minckwitz, G, Gelber, R D, Dowsett, M, Di Leo, A, Cameron, D, Baselga, J, Gnant, M, Goldhirsch, A, Norton, L, Piccart, M

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Somatic mutation, copy number and transcriptomic profiles of primary and matched metastatic estrogen receptor-positive breast cancers von Fumagalli, D., Wilson, T.R., Salgado, R., Lu, X., Yu, J., O'Brien, C., Walter, K., Huw, L.Y., Criscitiello, C., Laios, I., Jose, V., Brown, D.N., Rothé, F., Maetens, M., Zardavas, D., Savas, P., Larsimont, D., Piccart-Gebhart, M.J., Michiels, S., Lackner, M.R., Sotiriou, C., Loi, S.

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Small breast cancers: When and how to treat von Tryfonidis, K, Zardavas, D, Cardoso, F

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PG 12.03 Targeting HER2 in 2015 von Piccart-Gebhart, M, Zardavas, D

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Autoimmunity and benefit from trastuzumab treatment in breast cancer: Results from the HERA phase III trial von Sonnenblick, A., Bailey, A., Uziely, B., Untch, M., Smith, I., Gianni, L., Baselga, J., Jackisch, C., Cameron, D., Bell, R., Zardavas, D., Al-Sakaff, N., Gelber, R., Dowsett, M., Leyland-jones, B., Piccart, M., de Azambuja, E.

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Phase I trial combining temozolomide plus lapatinib for the treatment of brain metastases in patients with HER2-positive metastatic breast cancer: the LAPTEM trial von de Azambuja, E., Zardavas, D., Lemort, M., Rossari, J., Moulin, C., Buttice, A., D'Hondt, V., Lebrun, F., Lalami, Y., Cardoso, F., Sotiriou, C., Gil, T., Devriendt, D., Paesmans, M., Piccart-Gebhart, M., Awada, A.

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Controversial issues in early-stage breast cancer: a global collaborative survey, supported by the European Society for Medical Oncology (ESMO) von Zardavas, D., Ades, F., Spasojevic, I.B., Pugliano, L., Capelan, M., Paesmans, M., de Azambuja, E., Piccart, M.

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1835 Health-related quality of life in advanced breast cancer: A systematic review on reporting of methodological and clinical issues in randomized controlled trials von Zikos, E, Ghislain, I, Coens, C, Quinten, C, Balta, V, Tryfonidis, K, Piccart, M, Zardavas, D, Velikova, G, Nagele, E, Bjelic-Radisic, V, Cardoso, F, Sprangers, M, Bottomley, A

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Hurdles and delays in access to anti-cancer drugs in Europe von Ades, F, Zardavas, D, Senterre, C, de Azambuja, E, Eniu, A, Popescu, R, Piccart, M, Parent, F

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Adjuvant Ovarian Suppression in Premenopausal Breast Cancer von Francis, Prudence A, Regan, Meredith M, Fleming, Gini F, Láng, István, Ciruelos, Eva, Bellet, Meritxell, Bonnefoi, Hervé R, Climent, Miguel A, Da Prada, Gian Antonio, Burstein, Harold J, Martino, Silvana, Davidson, Nancy E, Geyer, Charles E, Walley, Barbara A, Coleman, Robert, Kerbrat, Pierre, Buchholz, Stefan, Ingle, James N, Winer, Eric P, Rabaglio-Poretti, Manuela, Maibach, Rudolf, Ruepp, Barbara, Giobbie-Hurder, Anita, Price, Karen N, Colleoni, Marco, Viale, Giuseppe, Coates, Alan S, Goldhirsch, Aron, Gelber, Richard D

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Significance of increased expression of decoy receptor 3 in chronic liver disease von Kim, S, Kotoula, V, Hytiroglou, P, Zardavas, D, Zhang, L

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133TiP A phase II trial of nivolumab + palbociclib + anastrozole in postmenopausal women with ER+/HER2– primary breast cancer: CheckMate 7A8 von Tolaney, S.M., Jerusalem, G., Salgado, R., Liu, X., Chen, T., Zhang, H., Roberts, M., Zardavas, D., Prat, A.

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Role of Targeted Therapy in the Treatment of Primary Breast Cancer von Zardavas, D., Piccart, M.J.

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134TiP A phase III trial of nivolumab with neoadjuvant chemotherapy and adjuvant endocrine therapy in ER+/HER2− primary breast cancer: CheckMate 7FL von Curigliano, G., McArthur, H., Harbeck, N., Pusztai, L., Delaloge, S., Letrent, K., Chen, T., Li, B., Tatsuoka, K., Zardavas, D., Loi, S.

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External Quality Assessment 2.0: The Importance of a Standardized Implementation of TILs for Daily and Trial Practices von Nauwelaers, Inne, Laudus, Nele, Peeters, Dieter, Acs, Balazs, Denkert, Carsten, Michiels, Stefan, Horlings, Hugo, Siziopikou, Kalliopi P., Ely, Scott, Zardavas, Dimitrios, Mustimbo, Roberts, Bartlett, John, Floris, Giuseppe, Hartman, Johan, van Deurzen, Carolien H. M., Ceusters, Dorien, Dequeker, Els, Salgado, Roberto

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Interobserver Agreement of PD-L1/SP142 Immunohistochemistry and Tumor-Infiltrating Lymphocytes (TILs) in Distant Metastases of Triple-Negative Breast Cancer: A Proof-of-Concept Stu... von Van Bockstal, Mieke R., Cooks, Maxine, Nederlof, Iris, Brinkhuis, Mariel, Dutman, Annemiek, Koopmans, Monique, Kooreman, Loes, van der Vegt, Bert, Verhoog, Leon, Vreuls, Celine, Westenend, Pieter, Kok, Marleen, van Diest, Paul J., Nauwelaers, Inne, Laudus, Nele, Denkert, Carsten, Rimm, David, Siziopikou, Kalliopi P., Ely, Scott, Zardavas, Dimitrios, Roberts, Mustimbo, Floris, Giuseppe, Hartman, Johan, Acs, Balazs, Peeters, Dieter, Bartlett, John M. S., Dequeker, Els, Salgado, Roberto, Giudici, Fabiola, Michiels, Stefan, Horlings, Hugo, van Deurzen, Carolien H. M.

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218PAutoimmunity and benefit from trastuzumab treatment in breast cancer: Results from the HERA phase III trial von Sonnenblick, A, Bailey, A, Uziely, B, Untch, M, Smith, I, Gianni, L, Baselga, J, Jackisch, C, Cameron, D, Bell, R, Zardavas, D, Al-Sakaff, N, Gelber, R, Dowsett, M, Leyland-jones, B, Piccart, M, de Azambuja, E

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Abstract P6-11-16: PYTHIA: A phase II study of palbociclib plus fulvestrant versus placebo plus fulvestrant for pretreated patients with ER+/HER2- metastatic breast cancer von Zardavas, D, Regan, M, Maibach, R, Ruepp, B, Hiltbrunner, A, Blacher, L, Goulioti, T, Gelber, R, Flamen, P, Piccart, M, Malorni, L

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Abstract OT3-05-08: PALLAS: PALbociclib CoLlaborative Adjuvant Study: A randomized phase 3 trial of palbociclib with standard adjuvant endocrine therapy versus standard adjuvant en... von Mayer, E, DeMichele, A, Gnant, M, Barry, W, Pfeiler, G, Metzger, O, Burstein, H, Miller, K, Rastogi, P, Loibl, S, Goulioti, T, Zardavas, D, Fesl, C, Koehler, M, Huang-Bartlett, C, Huang, X, Piccart, M, Winer, E, Wolff, A

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