Mitophagy and Alzheimer’s Disease: Cellular and Molecular Mechanisms von Kerr, Jesse S, Adriaanse, Bryan A, Greig, Nigel H, Mattson, Mark P, Cader, M. Zameel, Bohr, Vilhelm A, Fang, Evandro F

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Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease von Fang, Evandro F., Hou, Yujun, Palikaras, Konstantinos, Adriaanse, Bryan A., Kerr, Jesse S., Yang, Beimeng, Lautrup, Sofie, Hasan-Olive, Md Mahdi, Caponio, Domenica, Dan, Xiuli, Rocktäschel, Paula, Croteau, Deborah L., Akbari, Mansour, Greig, Nigel H., Fladby, Tormod, Nilsen, Hilde, Cader, M. Zameel, Mattson, Mark P., Tavernarakis, Nektarios, Bohr, Vilhelm A.

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Aneuploidy effects on human gene expression across three cell types von Liu, Siyuan, Akula, Nirmala, Reardon, Paul K, Russ, Jill, Torres, Erin, Clasen, Liv S, Blumenthal, Jonathan, Lalonde, Francois, McMahon, Francis J, Szele, Francis, Disteche, Christine M, Cader, M Zameel, Raznahan, Armin

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A causal role for TRESK loss of function in migraine mechanisms von Pettingill, Philippa, Weir, Greg A, Wei, Tina, Wu, Yukyee, Flower, Grace, Lalic, Tatjana, Handel, Adam, Duggal, Galbha, Chintawar, Satyan, Cheung, Jonathan, Arunasalam, Kanisa, Couper, Elizabeth, Haupt, Larisa M, Griffiths, Lyn R, Bassett, Andrew, Cowley, Sally A, Cader, M Zameel

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A Highly Efficient Human Pluripotent Stem Cell Microglia Model Displays a Neuronal-Co-culture-Specific Expression Profile and Inflammatory Response von Haenseler, Walther, Sansom, Stephen N., Buchrieser, Julian, Newey, Sarah E., Moore, Craig S., Nicholls, Francesca J., Chintawar, Satyan, Schnell, Christian, Antel, Jack P., Allen, Nicholas D., Cader, M. Zameel, Wade-Martins, Richard, James, William S., Cowley, Sally A.

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HDAC6 is a therapeutic target in mutant GARS-induced Charcot-Marie-Tooth disease von Benoy, Veronick, Van Helleputte, Lawrence, Prior, Robert, d'Ydewalle, Constantin, Haeck, Wanda, Geens, Natasja, Scheveneels, Wendy, Schevenels, Begga, Cader, M Zameel, Talbot, Kevin, Kozikowski, Alan P, Vanden Berghe, Pieter, Van Damme, Philip, Robberecht, Wim, Van Den Bosch, Ludo

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Altered neurochemical coupling in the occipital cortex in migraine with visual aura von Bridge, Holly, Stagg, Charlotte J, Near, Jamie, Lau, Chi-ieong, Zisner, Aimee, Cader, M. Zameel

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TRESK is a key regulator of nocturnal suprachiasmatic nucleus dynamics and light adaptive responses von Lalic, Tatjana, Steponenaite, Aiste, Wei, Liting, Vasudevan, Sridhar R., Mathie, Alistair, Peirson, Stuart N., Lall, Gurprit S., Cader, M. Zameel

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Rare variants in the CYP27B1 gene are associated with multiple sclerosis von Ramagopalan, Sreeram V., Dyment, David A., Cader, M. Zameel, Morrison, Katie M., Disanto, Giulio, Morahan, Julia M., Berlanga-Taylor, Antonio J., Handel, Adam, De Luca, Gabriele C., Sadovnick, A. Dessa, Lepage, Pierre, Montpetit, Alexandre, Ebers, George C.

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The molecular pathogenesis of migraine: new developments and opportunities von Zameel Cader, M

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Neuropilins lock secreted semaphorins onto plexins in a ternary signaling complex von Janssen, Bert J C, Malinauskas, Tomas, Weir, Greg A, Cader, M Zameel, Siebold, Christian, Jones, E Yvonne

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Targeted single-cell RNA sequencing of transcription factors enhances the identification of cell types and trajectories von Pokhilko, Alexandra, Handel, Adam E., Curion, Fabiola, Volpato, Viola, Whiteley, Emma S., Bostrand, Sunniva, Newey, Sarah E., Akerman, Colin J., Webber, Caleb, Clark, Michael B., Bowden, Rory, Cader, M. Zameel

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Assessing similarity to primary tissue and cortical layer identity in induced pluripotent stem cell-derived cortical neurons through single-cell transcriptomics von Handel, Adam E, Chintawar, Satyan, Lalic, Tatjana, Whiteley, Emma, Vowles, Jane, Giustacchini, Alice, Argoud, Karene, Sopp, Paul, Nakanishi, Mahito, Bowden, Rory, Cowley, Sally, Newey, Sarah, Akerman, Colin, Ponting, Chris P, Cader, M Zameel

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Next generation sequencing for molecular diagnosis of neurological disorders using ataxias as a model von Németh, Andrea H., Kwasniewska, Alexandra C., Lise, Stefano, Parolin Schnekenberg, Ricardo, Becker, Esther B. E., Bera, Katarzyna D., Shanks, Morag E., Gregory, Lorna, Buck, David, Zameel Cader, M., Talbot, Kevin, de Silva, Rajith, Fletcher, Nicholas, Hastings, Rob, Jayawant, Sandeep, Morrison, Patrick J., Worth, Paul, Taylor, Malcolm, Tolmie, John, O’Regan, Mary, Valentine, Ruth, Packham, Emily, Evans, Julie, Seller, Anneke, Ragoussis, Jiannis

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Patient fibroblast circadian rhythms predict lithium sensitivity in bipolar disorder von Sanghani, Harshmeena R., Jagannath, Aarti, Humberstone, Thomas, Ebrahimjee, Farid, Thomas, Justyn M., Churchill, Grant C., Cipriani, Andrea, Attenburrow, Mary-Jane, Perestenko, Olga V., Cowley, Sally A., Cader, M. Zameel, Peirson, Stuart N., Harrison, Paul J., Foster, Russell G., Goodwin, Guy M., Vasudevan, Sridhar R.

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Morphological analysis of neuromuscular junction development and degeneration in rodent lumbrical muscles von Sleigh, James N., Burgess, Robert W., Gillingwater, Thomas H., Cader, M. Zameel

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From Young to Old: Mimicking Neuronal Aging in Directly Converted Neurons from Young Donors von Varghese, Nimmy, Grimm, Amandine, Cader, M Zameel, Eckert, Anne

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Lipopolysaccharide distinctively alters human microglia transcriptomes to resemble microglia from Alzheimer's disease mouse models von Monzón-Sandoval, Jimena, Burlacu, Elena, Agarwal, Devika, Handel, Adam E, Wei, Liting, Davis, John, Cowley, Sally A, Cader, M Zameel, Webber, Caleb

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EBNA2 binds to genomic intervals associated with multiple sclerosis and overlaps with vitamin D receptor occupancy von Ricigliano, Vito A G, Handel, Adam E, Sandve, Geir K, Annibali, Viviana, Ristori, Giovanni, Mechelli, Rosella, Cader, M Zameel, Salvetti, Marco

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Plexin-Semaphorin Signaling Modifies Neuromuscular Defects in a Drosophila Model of Peripheral Neuropathy von Grice, Stuart J, Sleigh, James N, Zameel Cader, M

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