Loss of the Spinocerebellar Ataxia type 3 disease protein ATXN3 alters transcription of multiple signal transduction pathways von Zeng, Li, Zhang, Dapeng, McLoughlin, Hayley S, Zalon, Annie J, Aravind, L, Paulson, Henry L

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Impaired Autophagic-Lysosomal Fusion in Parkinson's Patient Midbrain Neurons Occurs through Loss of ykt6 and Is Rescued by Farnesyltransferase Inhibition von Pitcairn, Caleb, Murata, Naomi, Zalon, Annie J, Stojkovska, Iva, Mazzulli, Joseph R

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α-Synuclein: Multiple pathogenic roles in trafficking and proteostasis pathways in Parkinson’s disease von Zalon, Annie J., Quiriconi, Drew J., Pitcairn, Caleb, Mazzulli, Joseph R.

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Impaired Oligodendrocyte Maturation Is an Early Feature in SCA3 Disease Pathogenesis von Schuster, Kristen H, Zalon, Annie J, Zhang, Hongjiu, DiFranco, Danielle M, Stec, Nicholas R, Haque, Zaid, Blumenstein, Kate G, Pierce, Amanda M, Guan, Yuanfang, Paulson, Henry L, McLoughlin, Hayley S

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Antisense Oligonucleotide Silencing Reverses Abnormal Neurochemistry in Spinocerebellar Ataxia 3 Mice von McLoughlin, Hayley S, Gundry, Katherine, Rainwater, Orion, Schuster, Kristen H, Wellik, Isabel G, Zalon, Annie J, Benneyworth, Michael A, Eberly, Lynn E, Öz, Gülin

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ASOs are an effective treatment for disease-associated oligodendrocyte signatures in premanifest and symptomatic SCA3 mice von Schuster, Kristen H., Zalon, Annie J., DiFranco, Danielle M., Putka, Alexandra F., Stec, Nicholas R., Jarrah, Sabrina I., Naeem, Arsal, Haque, Zaid, Zhang, Hanrui, Guan, Yuanfang, McLoughlin, Hayley S.

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Antisense Oligonucleotide Therapy Targeted Against ATXN3 Improves Potassium Channel–Mediated Purkinje Neuron Dysfunction in Spinocerebellar Ataxia Type 3 von Bushart, David D., Zalon, Annie J., Zhang, Hongjiu, Morrison, Logan M., Guan, Yuanfang, Paulson, Henry L., Shakkottai, Vikram G., McLoughlin, Hayley S.

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ASO silencing reverses abnormal neurochemistry in spinocerebellar ataxia 3 mice von McLoughlin, Hayley S., Gundry, Katherine, Rainwater, Orion, Schuster, Kristen H., Wellik, Isabel G., Zalon, Annie J., Benneyworth, Michael A., Eberly, Lynn E., Öz, Gülin

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