Studying Pathogenetic Contribution of a Variant of Unknown Significance, p.M659I (c.1977G > A) in MYH7, to the Development of Hypertrophic Cardiomyopathy Using CRISPR/Cas9-Engineer... von Pavlova, Sophia V, Shulgina, Angelina E, Zakian, Suren M, Dementyeva, Elena V

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Mild phenotype of knockouts of the major apurinic/apyrimidinic endonuclease APEX1 in a non-cancer human cell line von Kim, Daria V, Kulishova, Liliya M, Torgasheva, Natalia A, Melentyev, Vasily S, Dianov, Grigory L, Medvedev, Sergey P, Zakian, Suren M, Zharkov, Dmitry O

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A dual origin of the Xist gene from a protein-coding gene and a set of transposable elements von Elisaphenko, Eugeny A, Kolesnikov, Nikolay N, Shevchenko, Alexander I, Rogozin, Igor B, Nesterova, Tatyana B, Brockdorff, Neil, Zakian, Suren M

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Introducing an expanded CAG tract into the huntingtin gene causes a wide spectrum of ultrastructural defects in cultured human cells von Morozova, Ksenia N, Suldina, Lyubov A, Malankhanova, Tuyana B, Grigor'eva, Elena V, Zakian, Suren M, Kiseleva, Elena, Malakhova, Anastasia A

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IPSC-Derived Astrocytes Contribute to In Vitro Modeling of Parkinson's Disease Caused by the GBA1 N370S Mutation von Yarkova, Elena S, Grigor'eva, Elena V, Medvedev, Sergey P, Pavlova, Sophia V, Zakian, Suren M, Malakhova, Anastasia A

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Mutant-Huntingtin Molecular Pathways Elucidate New Targets for Drug Repurposing von Makeeva, Vladlena S, Dyrkheeva, Nadezhda S, Lavrik, Olga I, Zakian, Suren M, Malakhova, Anastasia A

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Oxidative stress monitoring in iPSC-derived motor neurons using genetically encoded biosensors of H2O2 von Ustyantseva, Elizaveta, Pavlova, Sophia V., Malakhova, Anastasia A., Ustyantsev, Kirill, Zakian, Suren M., Medvedev, Sergey P.

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Generation of Transgenic Rat Embryonic Stem Cells Using the CRISPR/Cpf1 System for Inducible Gene Knockout von Sherstyuk, Vladimir V., Zakian, Suren M.

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Biochemical Characteristics of iPSC-Derived Dopaminergic Neurons from N370S GBA Variant Carriers with and without Parkinson's Disease von Grigor'eva, Elena V, Kopytova, Alena E, Yarkova, Elena S, Pavlova, Sophia V, Sorogina, Diana A, Malakhova, Anastasia A, Malankhanova, Tuyana B, Baydakova, Galina V, Zakharova, Ekaterina Y, Medvedev, Sergey P, Pchelina, Sofia N, Zakian, Suren M

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Design, Synthesis, and Biological Investigation of Novel Classes of 3-Carene-Derived Potent Inhibitors of TDP1 von Il'ina, Irina V, Dyrkheeva, Nadezhda S, Zakharenko, Alexandra L, Sidorenko, Alexander Yu, Li-Zhulanov, Nikolay S, Korchagina, Dina V, Chand, Raina, Ayine-Tora, Daniel M, Chepanova, Arina A, Zakharova, Olga D, Ilina, Ekaterina S, Reynisson, Jóhannes, Malakhova, Anastasia A, Medvedev, Sergey P, Zakian, Suren M, Volcho, Konstantin P, Salakhutdinov, Nariman F, Lavrik, Olga I

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Generation of iPSCs from a Patient with the M694V Mutation in the MEFV Gene Associated with Familial Mediterranean Fever and Their Differentiation into Macrophages von Grigor'eva, Elena V, Karapetyan, Lana V, Malakhova, Anastasia A, Medvedev, Sergey P, Minina, Julia M, Hayrapetyan, Varduhi H, Vardanyan, Valentina S, Zakian, Suren M, Arakelyan, Arsen, Zakharyan, Roksana

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Noncoding RNAs in the Regulation of Pluripotency and Reprogramming von Sherstyuk, Vladimir V, Medvedev, Sergey P, Zakian, Suren M

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Constitutive heterochromatin propagation contributes to the X chromosome inactivation von Shevchenko, Alexander I., Rifel, Nikita A., Zakian, Suren M., Zakharova, Irina S.

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Generation of three induced pluripotent stem cell lines (RAUi001-A, RAUi001-B and RAUi001-C) from peripheral blood mononuclear cells of a healthy Armenian individual von Grigor’eva, Elena V., Malakhova, Anastasia A., Ghukasyan, Lilit, Hayrapetyan, Varduhi, Atshemyan, Sofi, Vardanyan, Valentina, Zakian, Suren M., Zakharyan, Roksana, Arakelyan, Arsen

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iPSC-Derived Endothelial Cells Reveal LDLR Dysfunction and Dysregulated Gene Expression Profiles in Familial Hypercholesterolemia von Zakharova, Irina S, Shevchenko, Alexander I, Arssan, Mhd Amin, Sleptcov, Aleksei A, Nazarenko, Maria S, Zarubin, Aleksei A, Zheltysheva, Nina V, Shevchenko, Vlada A, Tmoyan, Narek A, Saaya, Shoraan B, Ezhov, Marat V, Kukharchuk, Valery V, Parfyonova, Yelena V, Zakian, Suren M

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Mapping of Replication Origins in the X Inactivation Center of Vole Microtus levis Reveals Extended Replication Initiation Zone von Sherstyuk, Vladimir V, Shevchenko, Alexander I, Zakian, Suren M

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Transcriptomic Analysis of CRISPR/Cas9-Mediated PARP1-Knockout Cells under the Influence of Topotecan and TDP1 Inhibitor von Dyrkheeva, Nadezhda S, Malakhova, Anastasia A, Zakharenko, Aleksandra L, Okorokova, Larisa S, Shtokalo, Dmitriy N, Pavlova, Sophia V, Medvedev, Sergey P, Zakian, Suren M, Nushtaeva, Anna A, Tupikin, Alexey E, Kabilov, Marsel R, Khodyreva, Svetlana N, Luzina, Olga A, Salakhutdinov, Nariman F, Lavrik, Olga I

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Calling and Phasing of Single-Nucleotide and Structural Variants of the LDLR Gene Using Oxford Nanopore MinION von Nazarenko, Maria S, Sleptcov, Aleksei A, Zarubin, Aleksei A, Salakhov, Ramil R, Shevchenko, Alexander I, Tmoyan, Narek A, Elisaphenko, Eugeny A, Zubkova, Ekaterina S, Zheltysheva, Nina V, Ezhov, Marat V, Kukharchuk, Valery V, Parfyonova, Yelena V, Zakian, Suren M, Zakharova, Irina S

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Induced pluripotent stem cell line ICGi038-A, obtained by reprogramming peripheral blood mononuclear cells from a patient with familial hypercholesterolemia due to compound heteroz... von Zakharova, Irina S., Shevchenko, Alexander I., Tmoyan, Narek A., Elisaphenko, Eugeny A., Zubkova, Ekaterina S., Sleptcov, Aleksei A., Nazarenko, Maria S., Ezhov, Marat V., Kukharchuk, Valery V., Parfyonova, Yelena V., Zakian, Suren M.

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Generation of GABAergic striatal neurons by a novel iPSC differentiation protocol enabling scalability and cryopreservation of progenitor cells von Grigor’eva, Elena V., Malankhanova, Tuyana B., Surumbayeva, Aizhan, Pavlova, Sophia V., Minina, Julia M., Kizilova, Elena A., Suldina, Lyubov A., Morozova, Ksenia N., Kiseleva, Elena, Sorokoumov, Eugeny D., Lebedev, Igor N., Zakian, Suren M., Malakhova, Anastasia A.

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