Novel Therapies for Relapsed and Refractory Neuroblastoma von Zage, Peter E

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Allele-specific expression reveals genes with recurrent cis-regulatory alterations in high-risk neuroblastoma von Sen, Arko, Huo, Yuchen, Elster, Jennifer, Zage, Peter E, McVicker, Graham

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Regorafenib is effective against neuroblastoma in vitro and in vivo and inhibits the RAS/MAPK, PI3K/Akt/mTOR and Fos/Jun pathways von Subramonian, Divya, Phanhthilath, Nikki, Rinehardt, Hannah, Flynn, Sean, Huo, Yuchen, Zhang, Jing, Messer, Karen, Mo, Qianxing, Huang, Shixia, Lesperance, Jacqueline, Zage, Peter E.

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UBE4B interacts with the ITCH E3 ubiquitin ligase to induce Ku70 and c-FLIPL polyubiquitination and enhanced neuroblastoma apoptosis von Le Clorennec, Christophe, Subramonian, Divya, Huo, Yuchen, Zage, Peter E.

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CD114: A New Member of the Neural Crest‐Derived Cancer Stem Cell Marker Family von Zage, Peter E., Whittle, Sarah B., Shohet, Jason M.

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UBE4B Protein Couples Ubiquitination and Sorting Machineries to Enable Epidermal Growth Factor Receptor (EGFR) Degradation von Sirisaengtaksin, Natalie, Gireud, Monica, Yan, Qing, Kubota, Yoshihisa, Meza, Denisse, Waymire, Jack C., Zage, Peter E., Bean, Andrew J.

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mTOR ATP-competitive inhibitor INK128 inhibits neuroblastoma growth via blocking mTORC signaling von Zhang, Huiyuan, Dou, Jun, Yu, Yang, Zhao, Yanling, Fan, Yihui, Cheng, Jin, Xu, Xin, Liu, Wei, Guan, Shan, Chen, Zhenghu, shi, Yan, Patel, Roma, Vasudevan, Sanjeev A., Zage, Peter E., Zhang, Hong, Nuchtern, Jed G., Kim, Eugene S., Fu, Songbin, Yang, Jianhua

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The Potential Functional Roles of NME1 Histidine Kinase Activity in Neuroblastoma Pathogenesis von Adam, Kevin, Lesperance, Jacqueline, Hunter, Tony, Zage, Peter E

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USP7 Inhibition Suppresses Neuroblastoma Growth via Induction of p53-Mediated Apoptosis and EZH2 and N-Myc Downregulation von Le Clorennec, Christophe, Lee, Karen, Huo, Yuchen, Zage, Peter E

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Treatment of recurrent diffuse intrinsic pontine glioma: the MD Anderson Cancer Center experience von Wolff, Johannes E., Rytting, Michael E., Vats, Tribhawan S., Zage, Peter E., Ater, Joann L., Woo, Shiao, Kuttesch, John, Ketonen, Leena, Mahajan, Anita

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New aspects of neuroblastoma treatment: ASPHO 2011 symposium review von Zage, Peter E., Louis, Chrystal U., Cohn, Susan L.

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Targeting the RET tyrosine kinase in neuroblastoma: A review and application of a novel selective drug design strategy von Steen, Erica A., Basilaia, Mariam, Kim, William, Getz, Taelor, Gustafson, Jeffrey L., Zage, Peter E.

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Identification of a novel gene signature for neuroblastoma differentiation using a Boolean implication network von Zage, Peter E., Huo, Yuchen, Subramonian, Divya, Le Clorennec, Christophe, Ghosh, Pradipta, Sahoo, Debashis

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Notch pathway activation induces neuroblastoma tumor cell growth arrest von Zage, Peter E., Nolo, Riitta, Fang, Wendy, Stewart, John, Garcia-Manero, Guillermo, Zweidler-McKay, Patrick A.

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Signaling of ERBB receptor tyrosine kinases promotes neuroblastoma growth in vitro and in vivo von Richards, Kristen N., Zweidler‐McKay, Patrick A., Van Roy, Nadine, Speleman, Frank, Trevino, Jesus, Zage, Peter E., Hughes, Dennis P. M.

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Identification and preclinical characterization of AZ-23, a novel, selective, and orally bioavailable inhibitor of the Trk kinase pathway von Thress, Kenneth, Macintyre, Terry, Wang, Haiyun, Whitston, Dave, Liu, Zhong-Ying, Hoffmann, Ethan, Wang, Tao, Brown, Jeffrey L, Webster, Kevin, Omer, Charles, Zage, Peter E, Zeng, Lizhi, Zweidler-McKay, Patrick A

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Binimetinib inhibits MEK and is effective against neuroblastoma tumor cells with low NF1 expression von Woodfield, Sarah E, Zhang, Linna, Scorsone, Kathleen A, Liu, Yin, Zage, Peter E

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A phase II trial of nifurtimox combined with topotecan and cyclophosphamide for refractory or relapsed neuroblastoma and medulloblastoma von Eslin, Don, Zage, Peter E., Bergendahl, Genevieve, Lewis, Elizabeth, Roberts, William, Kraveka, Jacqueline, Mitchell, Deanna, Isakoff, Michael S., Rawwas, Jawhar, Wada, Randal K., Fluchel, Mark, Brown, Valerie I., Ginn, Kevin, Higgins, Timothy, BeeravallyNagulapally, Abhinav, Dykema, Karl, Hanna, Gina, Ferguson, William, Saulnier Sholler, Giselle L.

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Sensitivity of neuroblastoma to the novel kinase inhibitor cabozantinib is mediated by ERK inhibition von Zhang, Linna, Scorsone, Kathleen, Woodfield, Sarah E., Zage, Peter E.

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Mechanisms of Efficacy of the FGFR1–3 Inhibitor AZD4547 in Pediatric Solid Tumor Models von Phanhthilath, Nikki, Hakim, Sara, Su, Catherine, Liu, Andrea, Subramonian, Divya, Lesperance, Jacqueline, Zage, Peter E.

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