Structure of CC chemokine receptor 2 with orthosteric and allosteric antagonists von Zheng, Yi, Qin, Ling, Zacarías, Natalia V. Ortiz, de Vries, Henk, Han, Gye Won, Gustavsson, Martin, Dabros, Marta, Zhao, Chunxia, Cherney, Robert J., Carter, Percy, Stamos, Dean, Abagyan, Ruben, Cherezov, Vadim, Stevens, Raymond C., IJzerman, Adriaan P., Heitman, Laura H., Tebben, Andrew, Kufareva, Irina, Handel, Tracy M.

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Sodium ion binding pocket mutations and adenosine A2A receptor function von Massink, Arnault, Gutiérrez-de-Terán, Hugo, Lenselink, Eelke B, Ortiz Zacarías, Natalia V, Xia, Lizi, Heitman, Laura H, Katritch, Vsevolod, Stevens, Raymond C, IJzerman, Adriaan P

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Anticancer opportunities at every stage of chemokine function von Ortiz Zacarías, Natalia V., Bemelmans, Martijn P., Handel, Tracy M., de Visser, Karin E., Heitman, Laura H.

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Intracellular Receptor Modulation: Novel Approach to Target GPCRs von Ortiz Zacarías, Natalia V., Lenselink, Eelke B., IJzerman, Adriaan P., Handel, Tracy M., Heitman, Laura H.

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A novel CCR2 antagonist inhibits atherogenesis in apoE deficient mice by achieving high receptor occupancy von Bot, Ilze, Ortiz Zacarías, Natalia V., de Witte, Wilhelmus E. A., de Vries, Henk, van Santbrink, Peter J., van der Velden, Daniël, Kröner, Mara J., van der Berg, Dirk-Jan, Stamos, Dean, de Lange, Elizabeth C. M., Kuiper, Johan, IJzerman, Adriaan P., Heitman, Laura H.

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Design and Characterization of an Intracellular Covalent Ligand for CC Chemokine Receptor 2 von Ortiz Zacarías, Natalia V, Chahal, Kirti K, Šimková, Tereza, van der Horst, Cas, Zheng, Yi, Inoue, Asuka, Theunissen, Emy, Mallee, Lloyd, van der Es, Daan, Louvel, Julien, IJzerman, Adriaan P, Handel, Tracy M, Kufareva, Irina, Heitman, Laura H

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Inducing Receptor Degradation as a Novel Approach to Target CC Chemokine Receptor 2 (CCR2) von Ortiz Zacarías, Natalia V, Röth, Sascha, Broekhuis, Jeremy D, van der Es, Daan, Moreau, Kevin, Heitman, Laura H

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Labeling of CC Chemokine Receptor 2 with a Versatile Intracellular Allosteric Probe von den Hollander, Lisa S., Beerkens, Bert L.H., Dekkers, Sebastian, van Veldhoven, Jacobus P.D., Ortiz Zacarías, Natalia V., van der Horst, Cas, Sieders, Elisabeth G., de Valk, Bert, Wang, Jianhui, IJzerman, Adriaan P., van der Es, Daan, Heitman, Laura H.

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Pyrrolone Derivatives as Intracellular Allosteric Modulators for Chemokine Receptors: Selective and Dual-Targeting Inhibitors of CC Chemokine Receptors 1 and 2 von Ortiz Zacarías, Natalia V, van Veldhoven, Jacobus P. D, Portner, Laura, van Spronsen, Eric, Ullo, Salviana, Veenhuizen, Margo, van der Velden, Wijnand J. C, Zweemer, Annelien J. M, Kreekel, Roy M, Oenema, Kenny, Lenselink, Eelke B, Heitman, Laura H, IJzerman, Adriaan P

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Fosfomycin: Pharmacological, Clinical and Future Perspectives von Dijkmans, Anneke Corinne, Zacarías, Natalia Veneranda Ortiz, Burggraaf, Jacobus, Mouton, Johan Willem, Wilms, Erik Bert, van Nieuwkoop, Cees, Touw, Daniel Johannes, Stevens, Jasper, Kamerling, Ingrid Maria Catharina

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Piperazine squaric acid diamides, a novel class of allosteric P2X7 receptor antagonists von Patberg, Marius, Isaak, Andreas, Füsser, Friederike, Ortiz Zacarías, Natalia V., Vinnenberg, Laura, Schulte, Janine, Michetti, Lucia, Grey, Lucie, van der Horst, Cas, Hundehege, Petra, Koch, Oliver, Heitman, Laura H., Budde, Thomas, Junker, Anna

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Synthesis and Pharmacological Evaluation of Triazolopyrimidinone Derivatives as Noncompetitive, Intracellular Antagonists for CC Chemokine Receptors 2 and 5 von Ortiz Zacarías, Natalia V, van Veldhoven, Jacobus P D, den Hollander, Lisa S, Dogan, Burak, Openy, Joseph, Hsiao, Ya-Yun, Lenselink, Eelke B, Heitman, Laura H, IJzerman, Adriaan P

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Fluorophore-Labeled Pyrrolones Targeting the Intracellular Allosteric Binding Site of the Chemokine Receptor CCR1 von Toy, Lara, Huber, Max E., Lee, Minhee, Bartolomé, Ana Alonso, Ortiz Zacarías, Natalia V., Nasser, Sherif, Scholl, Stephan, Zlotos, Darius P., Mandour, Yasmine M., Heitman, Laura H., Szpakowska, Martyna, Chevigné, Andy, Schiedel, Matthias

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Inhibition of macrophage migration in zebrafish larvae demonstrates in vivo efficacy of human CCR2 inhibitors von Sommer, Frida, Ortiz Zacarı́as, Natalia V., Heitman, Laura H., Meijer, Annemarie H.

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Development of the First Potential Nonpeptidic Positron Emission Tomography Tracer for the Imaging of CCR2 Receptors von Wagner, Stefan, Moura Gatti, Fernando, Silva, Daniel G., Ortiz Zacarias, Natalia V., Zweemer, Annelien J. M., Hermann, Sven, De Maria, Monica, Koch, Michael, Weiss, Christina, Schepmann, Dirk, Heitman, Laura H., Tschammer, Nuska, Kopka, Klaus, Junker, Anna

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Synthesis and biological evaluation of chemokine receptor ligands with 2-benzazepine scaffold von Thum, Simone, Kokornaczyk, Artur K., Seki, Tomoaki, De Maria, Monica, Ortiz Zacarias, Natalia V., de Vries, Henk, Weiss, Christina, Koch, Michael, Schepmann, Dirk, Kitamura, Masato, Tschammer, Nuska, Heitman, Laura H., Junker, Anna, Wünsch, Bernhard

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Fosfomycin as a potential therapy for the treatment of systemic infections: a population pharmacokinetic model to simulate multiple dosing regimens von Ortiz Zacarías, Natalia V., Dijkmans, Anneke C., Burggraaf, Jacobus, Mouton, Johan W., Wilms, Erik B., Nieuwkoop, Cees, Touw, Daan J., Kamerling, Ingrid M. C., Stevens, Jasper

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Desigualdad y segregación educativa durante la pandemia COVID 19 en Argentina von Romero, Claudia, Krichesky, Gabriela, Zacarías, Natalia

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Problemas de justicia social en el contexto educativo argentino. El caso del nivel secundario von Romero, Claudia, Krichesky, Gabriela, Zacarías, Natalia

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Sodium Ion Binding Pocket Mutations and Adenosine A 2A Receptor Function von Massink, Arnault, Gutiérrez-de-Terán, Hugo, Lenselink, Eelke B., Ortiz Zacarías, Natalia V., Xia, Lizi, Heitman, Laura H., Katritch, Vsevolod, Stevens, Raymond C., IJzerman, Adriaan P.

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