Shared genetic and epigenetic changes link aging and cancer von Zabransky, Daniel J., Jaffee, Elizabeth M., Weeraratna, Ashani T.

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ESR1 Mutations in Circulating Plasma Tumor DNA from Metastatic Breast Cancer Patients von Chu, David, Paoletti, Costanza, Gersch, Christina, VanDenBerg, Dustin A, Zabransky, Daniel J, Cochran, Rory L, Wong, Hong Yuen, Toro, Patricia Valda, Cidado, Justin, Croessmann, Sarah, Erlanger, Bracha, Cravero, Karen, Kyker-Snowman, Kelly, Button, Berry, Parsons, Heather A, Dalton, W Brian, Gillani, Riaz, Medford, Arielle, Aung, Kimberly, Tokudome, Nahomi, Chinnaiyan, Arul M, Schott, Anne, Robinson, Dan, Jacks, Karen S, Lauring, Josh, Hurley, Paula J, Hayes, Daniel F, Rae, James M, Park, Ben Ho

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Phenotypic and functional properties of Helios+ regulatory T cells von Zabransky, Daniel J, Nirschl, Christopher J, Durham, Nicholas M, Park, Ben V, Ceccato, Christina M, Bruno, Tullia C, Tam, Ada J, Getnet, Derese, Drake, Charles G

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Stromal changes in the aged lung induce an emergence from melanoma dormancy von Fane, Mitchell E., Chhabra, Yash, Alicea, Gretchen M., Maranto, Devon A., Douglass, Stephen M., Webster, Marie R., Rebecca, Vito W., Marino, Gloria E., Almeida, Filipe, Ecker, Brett L., Zabransky, Daniel J., Hüser, Laura, Beer, Thomas, Tang, Hsin-Yao, Kossenkov, Andrew, Herlyn, Meenhard, Speicher, David W., Xu, Wei, Xu, Xiaowei, Jaffee, Elizabeth M., Aguirre-Ghiso, Julio A., Weeraratna, Ashani T.

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HER2 Reactivation through Acquisition of the HER2 L755S Mutation as a Mechanism of Acquired Resistance to HER2-targeted Therapy in HER2 + Breast Cancer von Xu, Xiaowei, De Angelis, Carmine, Burke, Kathleen A, Nardone, Agostina, Hu, Huizhong, Qin, Lanfang, Veeraraghavan, Jamunarani, Sethunath, Vidyalakshmi, Heiser, Laura M, Wang, Nicholas, Ng, Charlotte K Y, Chen, Edward S, Renwick, Alexander, Wang, Tao, Nanda, Sarmistha, Shea, Martin, Mitchell, Tamika, Rajendran, Mahitha, Waters, Ian, Zabransky, Daniel J, Scott, Kenneth L, Gutierrez, Carolina, Nagi, Chandandeep, Geyer, Felipe C, Chamness, Gary C, Park, Ben H, Shaw, Chad A, Hilsenbeck, Susan G, Rimawi, Mothaffar F, Gray, Joe W, Weigelt, Britta, Reis-Filho, Jorge S, Osborne, C Kent, Schiff, Rachel

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Detection of Cancer DNA in Plasma of Patients with Early-Stage Breast Cancer von BEAVER, Julia A, JELOVAC, Danijela, CHU, David, BURNS, Timothy, HIGGINS, Michaela J, STEARNS, Vered, JACOBS, Lisa, HABIBI, Mehran, LANGE, Julie, HURLEY, Paula J, LAURING, Josh, VANDENBERG, Dustin A, BALUKRISHNA, Sasidharan, KESSLER, Jill, JETER, Stacie, SAMUELS, Michael L, MAAR, Dianna, COPE, Leslie, CIMINO-MATHEWS, Ashley, ARGANI, Pedram, WOLFF, Antonio C, BEN HO PARK, COCHRAN, Rory L, CROESSMANN, Sarah, ZABRANSKY, Daniel J, HONG YUEN WONG, TORO, Patricia Valda, CIDADO, Justin, BLAIR, Brian G

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Profiling of syngeneic mouse HCC tumor models as a framework to understand anti-PD-1 sensitive tumor microenvironments von Zabransky, Daniel J, Danilova, Ludmila, Leatherman, James M, Lopez-Vidal, Tamara Y, Sanchez, Jessica, Charmsaz, Soren, Gross, Nicole E, Shin, Sarah, Yuan, Xuan, Hernandez, Alexei, Yang, Hongqui, Xavier, Stephanie, Shu, Daniel, Saeed, Ali, Munjal, Kabeer, Kamdar, Zeal, Kagohara, Luciane T, Jaffee, Elizabeth M, Yarchoan, Mark, Ho, Won Jin

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Electron tomography of the contact between T cells and SIV/HIV-1: implications for viral entry von Sougrat, Rachid, Bartesaghi, Alberto, Lifson, Jeffrey D, Bennett, Adam E, Bess, Julian W, Zabransky, Daniel J, Subramaniam, Sriram

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HER2 missense mutations have distinct effects on oncogenic signaling and migration von Zabransky, Daniel J., Yankaskas, Christopher L., Cochran, Rory L., Wong, Hong Yuen, Croessmann, Sarah, Chu, David, Kavuri, Shyam M., Red Brewer, Monica, Rosen, D. Marc, Dalton, W. Brian, Cimino-Mathews, Ashley, Cravero, Karen, Button, Berry, Kyker-Snowman, Kelly, Cidado, Justin, Erlanger, Bracha, Parsons, Heather A., Manto, Kristen M., Bose, Ron, Lauring, Josh, Arteaga, Carlos L., Konstantopoulos, Konstantinos, Park, Ben Ho

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Strategies for Heating Up Cold Tumors to Boost Immunotherapies von Zabransky, Daniel J, Yarchoan, Mark, Jaffee, Elizabeth M

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Hotspot SF3B1 mutations induce metabolic reprogramming and vulnerability to serine deprivation von Dalton, W Brian, Helmenstine, Eric, Walsh, Noel, Gondek, Lukasz P, Kelkar, Dhanashree S, Read, Abigail, Natrajan, Rachael, Christenson, Eric S, Roman, Barbara, Das, Samarjit, Zhao, Liang, Leone, Robert D, Shinn, Daniel, Groginski, Taylor, Madugundu, Anil K, Patil, Arun, Zabransky, Daniel J, Medford, Arielle, Lee, Justin, Cole, Alex J, Rosen, Marc, Thakar, Maya, Ambinder, Alexander, Donaldson, Joshua, DeZern, Amy E, Cravero, Karen, Chu, David, Madero-Marroquin, Rafael, Pandey, Akhilesh, Hurley, Paula J, Lauring, Josh, Park, Ben Ho

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Aged fibroblast-derived extracellular vesicles promote angiogenesis in melanoma von Hüser, Laura, Chhabra, Yash, Gololobova, Olesia, Wang, Vania, Liu, Guanshu, Dixit, Agrani, Rocha, Murilo Ramos, Harper, Elizabeth I., Fane, Mitchell E., Marino-Bravante, Gloria E., Zabransky, Daniel J., Cai, Kathy Q., Utikal, Jochen, Slusher, Barbara S., Walston, Jeremy, Lipson, Evan J., Witwer, Kenneth W., Weeraratna, Ashani T.

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ERK hyperactivation serves as a unified mechanism of escape in intrinsic and acquired CDK4/6 inhibitor resistance in acral lentiginous melanoma von Jagirdar, Kasturee, Portuallo, Marie E., Wei, Meihan, Wilhide, Matthew, Bravo Narula, Jeremy A., Robertson, Bailey M., Alicea, Gretchen M., Aguh, Crystal, Xiao, Min, Godok, Tetiana, Fingerman, Dylan, Brown, Gregory Schuyler, Herlyn, Meenhard, Elad, Vissy M., Guo, Xinyu, Toska, Eneda, Zabransky, Daniel J., Wubbenhorst, Bradley, Nathanson, Katherine L., Kwatra, Shawn, Goyal, Yogesh, Ji, Hongkai, Liu, Qin, Rebecca, Vito W.

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Comparison of cell stabilizing blood collection tubes for circulating plasma tumor DNA von Toro, Patricia Valda, Erlanger, Bracha, Beaver, Julia A., Cochran, Rory L., VanDenBerg, Dustin A., Yakim, Elizabeth, Cravero, Karen, Chu, David, Zabransky, Daniel J., Wong, Hong Yuen, Croessmann, Sarah, Parsons, Heather, Hurley, Paula J., Lauring, Josh, Park, Ben Ho

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Immunotherapy response induces divergent tertiary lymphoid structure morphologies in hepatocellular carcinoma von Shu, Daniel H., Ho, Won Jin, Kagohara, Luciane T., Girgis, Alexander, Shin, Sarah M., Danilova, Ludmila, Lee, Jae W., Sidiropoulos, Dimitrios N., Mitchell, Sarah, Munjal, Kabeer, Howe, Kathryn, Bendinelli, Kayla J., Kartalia, Emma, Qi, Hanfei, Mo, Guanglan, Montagne, Janelle, Leatherman, James M., Lopez-Vidal, Tamara Y., Zhu, Qingfeng, Huff, Amanda L., Yuan, Xuan, Hernandez, Alexei, Coyne, Erin M., Zaidi, Neeha, Zabransky, Daniel J., Engle, Logan L., Ogurtsova, Aleksandra, Baretti, Marina, Laheru, Daniel, Durham, Jennifer N., Wang, Hao, Sunshine, Joel C., Johnston, Robert J., Deutsch, Julie Stein, Taube, Janis M., Anders, Robert A., Jaffee, Elizabeth M., Fertig, Elana J., Yarchoan, Mark

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Sex-dependent effects in the aged melanoma tumor microenvironment influence invasion and resistance to targeted therapy von Chhabra, Yash, Fane, Mitchell E., Pramod, Sneha, Hüser, Laura, Zabransky, Daniel J., Wang, Vania, Dixit, Agrani, Zhao, Ruzhang, Kumah, Edwin, Brezka, Megan L., Truskowski, Kevin, Nandi, Asmita, Marino-Bravante, Gloria E., Carey, Alexis E., Gour, Naina, Maranto, Devon A., Rocha, Murilo R., Harper, Elizabeth I., Ruiz, Justin, Lipson, Evan J., Jaffee, Elizabeth M., Bibee, Kristin, Sunshine, Joel C., Ji, Hongkai, Weeraratna, Ashani T.

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MACROD2 overexpression mediates estrogen independent growth and tamoxifen resistance in breast cancers von Mohseni, Morassa, Cidado, Justin, Croessmann, Sarah, Cravero, Karen, Cimino-Mathews, Ashley, Wong, Hong Yuen, Scharpf, Rob, Zabransky, Daniel J., Abukhdeir, Abde M., Garay, Joseph P., Wang, Grace M., Beaver, Julia A., Cochran, Rory L., Blair, Brian G., Rosen, D. Marc, Erlanger, Bracha, Argani, Pedram, Hurley, Paula J., Lauring, Josh, Park, Ben Ho

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Oncogene-induced matrix reorganization controls CD8+ T cell function in the soft-tissue sarcoma microenvironment von Fuller, Ashley M, Pruitt, Hawley C, Liu, Ying, Irizarry-Negron, Valerie M, Pan, Hehai, Song, Hoogeun, DeVine, Ann, Katti, Rohan S, Devalaraja, Samir, Ciotti, Gabrielle E, Gonzalez, Michael V, Williams, Erik F, Murazzi, Ileana, Ntekoumes, Dimitris, Skuli, Nicolas, Hakonarson, Hakon, Zabransky, Daniel J, Trevino, Jose G, Weeraratna, Ashani, Weber, Kristy, Haldar, Malay, Fraietta, Joseph A, Gerecht, Sharon, Eisinger-Mathason, T S Karin

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Whole-Exome Sequencing of Metaplastic Breast Carcinoma Indicates Monoclonality with Associated Ductal Carcinoma Component von Avigdor, Bracha Erlanger, Beierl, Katie, Gocke, Christopher D, Zabransky, Daniel J, Cravero, Karen, Kyker-Snowman, Kelly, Button, Berry, Chu, David, Croessmann, Sarah, Cochran, Rory L, Connolly, Roisin M, Park, Ben H, Wheelan, Sarah J, Cimino-Mathews, Ashley

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Hierarchical tumor heterogeneity mediated by cell contact between distinct genetic subclones von Karthikeyan, Swathi, Waters, Ian G, Dennison, Lauren, Chu, David, Donaldson, Joshua, Shin, Dong Ho, Rosen, D Marc, Gonzalez-Ericsson, Paula I, Sanchez, Violeta, Sanders, Melinda E, Pantone, Morgan V, Bergman, Riley E, Davidson, Brad A, Reed, Sarah C, Zabransky, Daniel J, Cravero, Karen, Kyker-Snowman, Kelly, Button, Berry, Wong, Hong Yuen, Hurley, Paula J, Croessmann, Sarah, Park, Ben Ho

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