The heterogeneity of pediatric MLL-rearranged acute myeloid leukemia von Balgobind, B V, Zwaan, C M, Pieters, R, Van den Heuvel-Eibrink, M M

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Prevalence and prognostic value of IDH1 and IDH2 mutations in childhood AML: a study of the AML–BFM and DCOG study groups von Damm, F, Thol, F, Hollink, I, Zimmermann, M, Reinhardt, K, van den Heuvel-Eibrink, M M, Zwaan, C M, de Haas, V, Creutzig, U, Klusmann, J-H, Krauter, J, Heuser, M, Ganser, A, Reinhardt, D, Thiede, C

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Outcome in children with Down's syndrome and acute lymphoblastic leukemia: role of IKZF1 deletions and CRLF2 aberrations von Buitenkamp, T D, Pieters, R, Gallimore, N E, van der Veer, A, Meijerink, J P P, Beverloo, H B, Zimmermann, M, de Haas, V, Richards, S M, Vora, A J, Mitchell, C D, Russell, L J, Schwab, C, Harrison, C J, Moorman, A V, van den Heuvel-Eibrink, M M, den Boer, M L, Zwaan, C M

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The novel calicheamicin-conjugated CD22 antibody inotuzumab ozogamicin (CMC-544) effectively kills primary pediatric acute lymphoblastic leukemia cells von de Vries, J F, Zwaan, C M, De Bie, M, Voerman, J S A, den Boer, M L, van Dongen, J J M, van der Velden, V H J

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Gene expression profiling in MDS and AML: potential and future avenues von Theilgaard-Mönch, K, Boultwood, J, Ferrari, S, Giannopoulos, K, Hernandez-Rivas, J M, Kohlmann, A, Morgan, M, Porse, B, Tagliafico, E, Zwaan, C M, Wainscoat, J, Van den Heuvel-Eibrink, M M, Mills, K, Bullinger, L

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Aurora kinases in childhood acute leukemia: the promise of aurora B as therapeutic target von Hartsink-Segers, S A, Zwaan, C M, Exalto, C, Luijendijk, M W J, Calvert, V S, Petricoin, E F, Evans, W E, Reinhardt, D, de Haas, V, Hedtjärn, M, Hansen, B R, Koch, T, Caron, H N, Pieters, R, Den Boer, M L

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Favorable prognostic impact of NPM1 gene mutations in childhood acute myeloid leukemia, with emphasis on cytogenetically normal AML von Hollink, I H I M, Zwaan, C M, Zimmermann, M, Arentsen-Peters, T C J M, Pieters, R, Cloos, J, Kaspers, G J L, de Graaf, S S N, Harbott, J, Creutzig, U, Reinhardt, D, van den Heuvel-Eibrink, M M, Thiede, C

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Low frequency of DNMT3A mutations in pediatric AML, and the identification of the OCI-AML3 cell line as an in vitro model von Hollink, I H I M, Feng, Q, Danen-van Oorschot, A A, Arentsen-Peters, S T C J M, Verboon, L J, Zhang, P, de Haas, V, Reinhardt, D, Creutzig, U, Trka, J, Pieters, R, van den Heuvel-Eibrink, M M, Wang, J, Zwaan, C M

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The MLL recombinome of acute leukemias in 2017 von Meyer, C, Burmeister, T, Gröger, D, Tsaur, G, Fechina, L, Renneville, A, Sutton, R, Venn, N C, Emerenciano, M, Pombo-de-Oliveira, M S, Barbieri Blunck, C, Almeida Lopes, B, Zuna, J, Trka, J, Ballerini, P, Lapillonne, H, De Braekeleer, M, Cazzaniga, G, Corral Abascal, L, van der Velden, V H J, Delabesse, E, Park, T S, Oh, S H, Silva, M L M, Lund-Aho, T, Juvonen, V, Moore, A S, Heidenreich, O, Vormoor, J, Zerkalenkova, E, Olshanskaya, Y, Bueno, C, Menendez, P, Teigler-Schlegel, A, zur Stadt, U, Lentes, J, Göhring, G, Kustanovich, A, Aleinikova, O, Schäfer, B W, Kubetzko, S, Madsen, H O, Gruhn, B, Duarte, X, Gameiro, P, Lippert, E, Bidet, A, Cayuela, J M, Clappier, E, Alonso, C N, Zwaan, C M, van den Heuvel-Eibrink, M M, Izraeli, S, Trakhtenbrot, L, Archer, P, Hancock, J, Möricke, A, Alten, J, Schrappe, M, Stanulla, M, Strehl, S, Attarbaschi, A, Dworzak, M, Haas, O A, Panzer-Grümayer, R, Sedék, L, Szczepański, T, Caye, A, Suarez, L, Cavé, H, Marschalek, R

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3-Methoxytyramine: An independent prognostic biomarker that associates with high-risk disease and poor clinical outcome in neuroblastoma patients von Verly, I.R.N., van Kuilenburg, A.B.P., Abeling, N.G.G.M., Goorden, S.M.I., Fiocco, M., Vaz, F.M., van Noesel, M.M., Zwaan, C.M., Kaspers, G.J.L., Merks, J.H.M., Caron, H.N., Tytgat, G.A.M.

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Standardization of WT1 mRNA quantitation for minimal residual disease monitoring in childhood AML and implications of WT1 gene mutations: a European multicenter study von Willasch, A M, Gruhn, B, Coliva, T, Kalinova, M, Schneider, G, Kreyenberg, H, Steinbach, D, Weber, G, Hollink, I H I M, Zwaan, C M, Biondi, A, van der Velden, V H J, Reinhardt, D, Cazzaniga, G, Bader, P, Trka, J

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Causes of death - other than progressive leukemia - in childhood acute lymphoblastic (ALL) and myeloid leukemia (AML): the Dutch Childhood Oncology Group experience von SLATS, A. M, EGELER, R. M, VAN DER DOES-VAN DEN BERG, A, KORBIJN, C, HÄHLEN, K, KAMPS, W. A, VEERMAN, A. J. P, ZWAAN, C. M

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TET2 mutations in childhood leukemia von Langemeijer, S M C, Jansen, J H, Hooijer, J, van Hoogen, P, Stevens-Linders, E, Massop, M, Waanders, E, van Reijmersdal, S V, Stevens-Kroef, M J P L, Zwaan, C M, van den Heuvel-Eibrink, M M, Sonneveld, E, Hoogerbrugge, P M, Geurts van Kessel, A, Kuiper, R P

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Myeloid leukemia in children 4 years or older with Down syndrome often lacks GATA1 mutation and cytogenetics and risk of relapse are more akin to sporadic AML von Hasle, H, Abrahamsson, J, Arola, M, Karow, A, O'Marcaigh, A, Reinhardt, D, Webb, D K H, van Wering, E, Zeller, B, Zwaan, C M, Vyas, P

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Frequency and prognostic implications of JAK 1-3 aberrations in Down syndrome acute lymphoblastic and myeloid leukemia von Blink, M, Buitenkamp, T D, van den Heuvel-Eibrink, M M, Danen-van Oorschot, A A, de Haas, V, Reinhardt, D, Klusmann, J-H, Zimmermann, M, Devidas, M, Carroll, A J, Basso, G, Pession, A, Hasle, H, Pieters, R, Rabin, K R, Izraeli, S, Zwaan, C M

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RAS pathway mutations as a predictive biomarker for treatment adaptation in pediatric B-cell precursor acute lymphoblastic leukemia von Jerchel, I S, Hoogkamer, A Q, Ariës, I M, Steeghs, E M P, Boer, J M, Besselink, N J M, Boeree, A, van de Ven, C, de Groot-Kruseman, H A, de Haas, V, Horstmann, M A, Escherich, G, Zwaan, C M, Cuppen, E, Koudijs, M J, Pieters, R, den Boer, M L

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Targeting acute myeloid leukemia by drug-induced c-MYB degradation von Walf-Vorderwülbecke, V, Pearce, K, Brooks, T, Hubank, M, van den Heuvel-Eibrink, M M, Zwaan, C M, Adams, S, Edwards, D, Bartram, J, Samarasinghe, S, Ancliff, P, Khwaja, A, Goulden, N, Williams, G, de Boer, J, Williams, O

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High BRE expression in pediatric MLL-rearranged AML is associated with favorable outcome von Balgobind, B V, Zwaan, C M, Reinhardt, D, Arentsen-Peters, T J C M, Hollink, I H I M, de Haas, V, Kaspers, G J L, de Bont, E S J M, Baruchel, A, Stary, J, Meyer, C, Marschalek, R, Creutzig, U, den Boer, M L, Pieters, R, van den Heuvel-Eibrink, M M

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Improved survival for children and young adolescents with acute myeloid leukemia: a Dutch study on incidence, survival and mortality von Reedijk, A. M. J., Klein, K., Coebergh, J. W. W., Kremer, L. C., Dinmohamed, A. G., de Haas, V., Versluijs, A. B., Ossenkoppele, G. J., Beverloo, H. B., Pieters, R., Zwaan, C. M., Kaspers, G. J. L., Karim-Kos, H. E.

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Successful use of indwelling tunneled catheters for the management of effusions in children with advanced cancer von den Hollander, Barbara S., Connolly, Bairbre L., Sung, Lillian, Rapoport, Adam, Zwaan, C.M., Grant, Ronald M., Parra, Dimitri, Temple, Michael J.

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