8R-Lisuride Is a Potent Stereospecific Histamine H1-Receptor Partial Agonist von Bakker, R.A., Weiner, D.M., ter Laak, T., Beuming, T., Zuiderveld, O.P., Edelbroek, M., Hacksell, U., Timmerman, H., Brann, M.R., Leurs, R.

Volltext

Evaluation of the receptor selectivity of the H3 receptor antagonists, iodophenpropit and thioperamide: an interaction with the 5‐HT3 receptor revealed von Leurs, Rob, Tulp, Martin Th.M., Menge, Wiro M.B.P., Adolfs, Martin J.P., Zuiderveld, Obbe P., Timmerman, Hendrik

Volltext

Histamine H1 receptor ligands. Part I. Novel thiazol-4-ylethanamine derivatives : synthesis and in vitro pharmacology von WALCZYNSKI, K, TIMMERMAN, H, ZUIDERVELD, O. P, ZHANG, M. Q, GLINKA, R

Volltext

Non-Imidazole Histamine H3 Ligands, Part 2: New 2-Substituted Benzothiazoles as Histamine H3 Antagonists von Walczynski, Krzysztof, Guryn, Roman, Zuiderveld, Obbe P., Timmerman, Henk

Volltext

Characterization of the Binding Site of the Histamine H3 Receptor. 1. Various Approaches to the Synthesis of 2-(1H-Imidazol-4-yl)cyclopropylamine and Histaminergic Activity of (1R,... von De Esch, Iwan J. P, Vollinga, Roeland C, Goubitz, Kees, Schenk, Henk, Appelberg, Ulf, Hacksell, Uli, Lemstra, Sylvia, Zuiderveld, Obbe P, Hoffmann, Marcel, Leurs, Rob, Menge, Wiro M. P. B, Timmerman, Henk

Volltext

Pharmacological characterisation of the histamine H3 receptor in the rat hippocampus von ALVES-RODRIGUES, A, TIMMERMAN, H, WILLEMS, E, LEMSTRA, S, ZUIDERVELD, O. P, LEURS, R

Volltext

Screening of cattle urine samples for the presence of beta-agonists with a functional test : some preliminary results von SCHILT, R, HOOIJERINK, H, HUF, F. A, ZUIDERVELD, O. P, BAST, A

Volltext

Non-imidazole histamine H3 ligands. Part I. Synthesis of 2-(1-piperazinyl)- and 2-(hexahydro-1H-1,4-diazepin-1-yl)benzothiazole derivatives as H3-antagonists with H1 blocking activ... von WALCZYNSKI, K, GURYN, R, ZUIDERVELD, O. P, TIMMERMAN, H

Volltext

Opioids activate brain analgesic circuits through cytochrome P450/epoxygenase signaling von Ding, Xinxin, Hough, Lindsay B, Conroy, Jennie L, Fang, Cheng, Gu, Jun, Zeitlin, Scott O, Yang, Weizhu, Yang, Jun, VanAlstine, Melissa A, Nalwalk, Julia W, Albrecht, Phillip J, Mazurkiewicz, Joseph E, Snyder-Keller, Abigail, Shan, Zhixing, Zhang, Shao-Zhong, Wentland, Mark P, Behr, Melissa, Knapp, Brian I, Bidlack, Jean M, Zuiderveld, Obbe P, Leurs, Rob

Volltext

In vitro effect of toluene diisocyanate on beta adrenergic and muscarinic receptor function in lung tissue of the rat von Borm, P J, Bast, A, Zuiderveld, O P

Volltext

Non-imidazole histamine H 3 ligands. Part III. New 4- n-propylpiperazines as non-imidazole histamine H 3-antagonists von Walczyński, Krzysztof, Zuiderveld, Obbe P., Timmerman, Henk

Volltext

Synthesis and pharmacological evaluation of some amino-acid-containing cyproheptadine derivatives as dual antagonists of histamine H1- and leukotriene D4-receptors von Zhang, MQ, van de Stolpe, A, Zuiderveld, OP, Timmerman, H

Volltext

Effect of inhibitors of enkephalin degradation in the isolated guinea-pig ileum von van Amsterdam, Jan G.C., van Buuren, Karel J.H., Krielaart, Marco J., Zuiderveld, Obbe P., Tijms, Rob P.J.H.

Volltext

N -Substituted Piperidinyl Alkyl Imidazoles:  Discovery of Methimepip as a Potent and Selective Histamine H 3 Receptor Agonist von Kitbunnadaj, Ruengwit, Hashimoto, Takeshi, Poli, Enzo, Zuiderveld, Obbe P., Menozzi, Alessandro, Hidaka, Ryoko, de Esch, Iwan J. P., Bakker, Remko A., Menge, Wiro M. P. B., Yamatodani, Atsushi, Coruzzi, Gabriella, Timmerman, Henk, Leurs, Rob

Volltext

Identification of 4-(1 H -Imidazol-4(5)-ylmethyl)pyridine (Immethridine) as a Novel, Potent, and Highly Selective Histamine H 3 Receptor Agonist von Kitbunnadaj, Ruengwit, Zuiderveld, Obbe P., Christophe, Bernard, Hulscher, Saskia, Menge, Wiro M. P. B., Gelens, Edith, Snip, Erwin, Bakker, Remko A., Celanire, Sylvain, Gillard, Michel, Talaga, Patrice, Timmerman, Henk, Leurs, Rob

Volltext

A Selective Human H 4 -Receptor Agonist:  (−)-2-Cyano-1-methyl-3-{(2 R ,5 R )-5- [1 H -imidazol-4(5)-yl]tetrahydrofuran-2-yl}methylguanidine von Hashimoto, Takeshi, Harusawa, Shinya, Araki, Lisa, Zuiderveld, Obbe P., Smit, Martine J., Imazu, Tomonari, Takashima, Seiichiroh, Yamamoto, Yumiko, Sakamoto, Yasuhiko, Kurihara, Takushi, Leurs, Rob, Bakker, Remko A., Yamatodani, Atsushi

Volltext

Synthesis and Structure−Activity Relationships of Conformationally Constrained Histamine H 3 Receptor Agonists von Kitbunnadaj, Ruengwit, Zuiderveld, Obbe P., De Esch, Iwan J. P., Vollinga, Roeland C., Bakker, Remko, Lutz, Martin, Spek, Anthony L., Cavoy, Emile, Deltent, Marie-France, Menge, Wiro M. P. B., Timmerman, Henk, Leurs, Rob

Volltext

8R-Lisuride Is a Potent Stereospecific Histamine H 1 -Receptor Partial Agonist von Bakker, R. A., Weiner, D. M., ter Laak, T., Beuming, T., Zuiderveld, O. P., Edelbroek, M., Hacksell, U., Timmerman, H., Brann, M. R., Leurs, R.

Volltext

Pharmacological characterisation of the histamine H sub(3) receptor in the rat hippocampus von Alves-Rodrigues, A, Timmerman, H, Willems, E, Lemstra, S, Zuiderveld, O P, Leurs, R

Volltext

Characterization of the Binding Site of the Histamine H 3 Receptor. 1. Various Approaches to the Synthesis of 2-(1 H -Imidazol-4-yl)cyclopropylamine and Histaminergic Activity of (... von De Esch, Iwan J. P., Vollinga, Roeland C., Goubitz, Kees, Schenk, Henk, Appelberg, Ulf, Hacksell, Uli, Lemstra, Sylvia, Zuiderveld, Obbe P., Hoffmann, Marcel, Leurs, Rob, Menge, Wiro M. P. B., Timmerman, Henk

Volltext