From Screening to Targeted Degradation: Strategies for the Discovery and Optimization of Small Molecule Ligands for PCSK9 von Petrilli, Whitney L., Adam, Gregory C., Erdmann, Roman S., Abeywickrema, Pravien, Agnani, Vijayalakshmi, Ai, Xi, Baysarowich, Jen, Byrne, Noel, Caldwell, John P., Chang, Wonsuk, DiNunzio, Edward, Feng, Zhe, Ford, Rachael, Ha, Sookhee, Huang, Yongcheng, Hubbard, Brian, Johnston, Jennifer M., Kavana, Michael, Lisnock, Jean-Marie, Liang, Rui, Lu, Jun, Lu, Zhijian, Meng, Juncai, Orth, Peter, Palyha, Oksana, Parthasarathy, Gopal, Salowe, Scott P., Sharma, Sujata, Shipman, Jennifer, Soisson, Stephen M., Strack, Alison M., Youm, Hyewon, Zhao, Kake, Zink, Deborah L., Zokian, Hratch, Addona, George H., Akinsanya, Karen, Tata, James R., Xiong, Yusheng, Imbriglio, Jason E.

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Isolation and Structure of Platencin: A FabH and FabF Dual Inhibitor with Potent Broad-Spectrum Antibiotic Activity von Jayasuriya, Hiranthi, Herath, Kithsiri B., Zhang, Chaowei, Zink, Deborah L., Basilio, Angela, Genilloud, Olga, Diez, Maria Teresa, Vicente, Francisca, Gonzalez, Ignacio, Salazar, Oscar, Pelaez, Fernando, Cummings, Richard, Ha, Sookhee, Wang, Jun, Singh, Sheo B.

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Isolation, Structure, and Absolute Stereochemistry of Platensimycin, A Broad Spectrum Antibiotic Discovered Using an Antisense Differential Sensitivity Strategy von Singh, Sheo B, Jayasuriya, Hiranthi, Ondeyka, John G, Herath, Kithsiri B, Zhang, Chaowei, Zink, Deborah L, Tsou, Nancy N, Ball, Richard G, Basilio, Angela, Genilloud, Olga, Diez, Maria Teresa, Vicente, Francisca, Pelaez, Fernando, Young, Katherine, Wang, Jun

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From Screening to Targeted Degradation: Strategies for the Discovery and Optimization of Small Molecule Ligands for PCSK9 von Petrilli, Whitney L., Adam, Gregory C., Erdmann, Roman S., Abeywickrema, Pravien, Agnani, Vijayalakshmi, Ai, Xi, Baysarowich, Jen, Byrne, Noel, Caldwell, John P., Chang, Wonsuk, DiNunzio, Edward, Feng, Zhe, Ford, Rachael, Ha, Sookhee, Huang, Yongcheng, Hubbard, Brian, Johnston, Jennifer M., Kavana, Michael, Lisnock, Jean-Marie, Liang, Rui, Lu, Jun, Lu, Zhijian, Meng, Juncai, Orth, Peter, Palyha, Oksana, Parthasarathy, Gopal, Salowe, Scott P., Sharma, Sujata, Shipman, Jennifer, Soisson, Stephen M., Strack, AlisonM, Youm, Hyewon, Zhao, Kake, Zink, Deborah L., Zokian, Hratch, Addona, George H., Akinsanya, Karen, Tata, James R., Xiong, Yusheng, Imbriglio, Jason E.

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Platensimycin and Platencin Congeners from Streptomyces platensis von Zhang, Chaowei, Ondeyka, John, Herath, Kithsiri, Jayasuriya, Hiranthi, Guan, Ziqiang, Zink, Deborah L, Dietrich, Lisa, Burgess, Bruce, Ha, Sookhee N, Wang, Jun, Singh, Sheo B

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Isolation, structure elucidation and antibacterial activity of a new tetramic acid, ascosetin von Ondeyka, John G, Smith, Scott K, Zink, Deborah L, Vicente, Francisca, Basilio, Angela, Bills, Gerald F, Polishook, Jon D, Garlisi, Charles, Mcguinness, Debra, Smith, Elizabeth, Qiu, Hongchen, Gill, Charles J, Donald, Robert GK, Phillips, John W, Goetz, Michael A, Singh, Sheo B

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Isolation, Structure Elucidation, and Biological Activity of Altersolanol P Using Staphylococcus aureus Fitness Test Based Genome-Wide Screening von Ondeyka, John, Buevich, Alexei V, Williamson, R. Thomas, Zink, Deborah L, Polishook, Jon D, Occi, James, Vicente, Francisca, Basilio, Angela, Bills, Gerald F, Donald, Robert G. K, Phillips, John W, Goetz, Michael A, Singh, Sheo B

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Isolation, structure and fatty acid synthesis inhibitory activities of platensimycin B1-B3 from Streptomyces platensis von Zhang, Chaowei, Ondeyka, John, Zink, Deborah L, Burgess, Bruce, Wang, Jun, Singh, Sheo B

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Isolation, Structure Elucidation, and Antibacterial Activity of Methiosetin, a Tetramic Acid from a Tropical Sooty Mold (Capnodium sp.) von Herath, Kithsiri, Jayasuriya, Hiranthi, Zink, Deborah L, Sigmund, Jan, Vicente, Francisca, de la Cruz, Mercedes, Basilio, Angela, Bills, Gerald F, Polishook, Jon D, Donald, Robert, Phillips, John, Goetz, Michael, Singh, Sheo B

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Kibdelomycin A, a congener of kibdelomycin, derivatives and their antibacterial activities von Singh, Sheo B., Goetz, Michael A., Smith, Scott K., Zink, Deborah L., Polishook, Jon, Onishi, Russell, Salowe, Scott, Wiltsie, Judyann, Allocco, John, Sigmund, Janet, Dorso, Karen, de la Cruz, Mercedes, Martín, Jesús, Vicente, Francisca, Genilloud, Olga, Donald, Robert G.K., Phillips, John W.

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In Vitro Assays for the Discovery of PCSK9 Autoprocessing Inhibitors von Salowe, Scott P., Zhang, Lei, Zokian, Hratch J., Gesell, Jennifer J., Zink, Deborah L., Wiltsie, Judyann, Ai, Xi, Kavana, Michael, Pinto, Shirly

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Anthelmintic constituents of Clonostachys candelabrum von Ayers, Sloan, Zink, Deborah L, Mohn, Kenneth, Powell, Joanne S, Brown, Christine M, Bills, Gerald, Grund, Alan, Thompson, Donald, Singh, Sheo B

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Isolation, Structure, and Antibacterial Activity of Philipimycin, A Thiazolyl Peptide Discovered from Actinoplanes philippinensis MA7347 von Zhang, Chaowei, Occi, James, Masurekar, Prakash, Barrett, John F, Zink, Deborah L, Smith, Scott, Onishi, Russell, Ha, Sookhee, Salazar, Oscar, Genilloud, Olga, Basilio, Angela, Vicente, Francisca, Gill, Charles, Hickey, Emily J, Dorso, Karen, Motyl, Mary, Singh, Sheo B

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Structure and Semisynthesis of Platensimide A, Produced by Streptomyces platensis von Herath, Kithsiri B, Zhang, Chaowei, Jayasuriya, Hiranthi, Ondeyka, John G, Zink, Deborah L, Burgess, Bruce, Wang, Jun, Singh, Sheo B

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Occurrence, distribution, dereplication and efficient discovery of thiazolyl peptides by sensitive-resistant pair screening von Singh, Sheo B, Zhang, Chaowei, Zink, Deborah L, Herath, Kithsiri, Ondeyka, John, Masurekar, Prakash, Jayasuriya, Hiranthi, Goetz, Michael A, Tormo, Jose Rubén, Vicente, Francisca, Martín, Jesús, González, Ignacio, Genilloud, Olga

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Discovery and antibacterial activity of glabramycin A–C from Neosartorya glabra by an antisense strategy von Jayasuriya, Hiranthi, Zink, Deborah, Basilio, Angela, Vicente, Francisca, Collado, Javier, Bills, Gerald, Goldman, Mary Lee, Motyl, Mary, Huber, Joann, Dezeny, Gabe, Byrne, Kevin, Singh, Sheo B

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Isolation, Structure, and Antibacterial Activities of Lucensimycins D−G, Discovered from Streptomyces lucensis MA7349 Using an Antisense Strategy von Singh, Sheo B, Zink, Deborah L, Dorso, Karen, Motyl, Mary, Salazar, Oscar, Basilio, Angela, Vicente, Francisca, Byrne, Kevin M, Ha, Sookhee, Genilloud, Olga

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Isolation, Structure, and Biological Activities of Fellutamides C and D from an Undescribed Metulocladosporiella (Chaetothyriales) Using the Genome-Wide Candida albicans Fitness Te... von Xu, Deming, Ondeyka, John, Harris, Guy H, Zink, Deborah, Kahn, Jennifer Nielsen, Wang, Hao, Bills, Gerald, Platas, Gonzalo, Wang, Wenxian, Szewczak, Alexander A, Liberator, Paul, Roemer, Terry, Singh, Sheo B

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Thiazomycins, Thiazolyl Peptide Antibiotics from Amycolatopsis fastidiosa von Zhang, Chaowei, Herath, Kithsiri, Jayasuriya, Hiranthi, Ondeyka, John G, Zink, Deborah L, Occi, James, Birdsall, Gwyneth, Venugopal, Jayashree, Ushio, Misti, Burgess, Bruce, Masurekar, Prakash, Barrett, John F, Singh, Sheo B

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Isolation, enzyme-bound structure and antibacterial activity of platencin from Streptomyces platensis von SINGH, Sheo B, ONDEYKA, John G, HERATH, Kithsiri B, CHAOWEI ZHANG, JAYASURIYA, Hiranthi, ZINK, Deborah L, PARTHASARATHY, Gopalakrishnan, BECKER, Joseph W, JUN WANG, SOISSON, Stephen M

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