Hematopoietic stem cell injury induced by ionizing radiation von Shao, Lijian, Luo, Yi, Zhou, Daohong

Volltext

Ionizing Radiation-Induced Endothelial Cell Senescence and Cardiovascular Diseases von Wang, Yingying, Boerma, Marjan, Zhou, Daohong

Volltext

PROteolysis TArgeting Chimeras (PROTACs) as emerging anticancer therapeutics von Khan, Sajid, He, Yonghan, Zhang, Xuan, Yuan, Yaxia, Pu, Shaoyan, Kong, Qingpeng, Zheng, Guangrong, Zhou, Daohong

Volltext

Targeting KRAS in pancreatic cancer: Emerging therapeutic strategies von Khan, Sajid, Budamagunta, Vivekananda, Zhou, Daohong

Volltext

Cellular Senescence Promotes Adverse Effects of Chemotherapy and Cancer Relapse von Demaria, Marco, O'Leary, Monique N, Chang, Jianhui, Shao, Lijian, Liu, Su, Alimirah, Fatouma, Koenig, Kristin, Le, Catherine, Mitin, Natalia, Deal, Allison M, Alston, Shani, Academia, Emmeline C, Kilmarx, Sumner, Valdovinos, Alexis, Wang, Boshi, de Bruin, Alain, Kennedy, Brian K, Melov, Simon, Zhou, Daohong, Sharpless, Norman E, Muss, Hyman, Campisi, Judith

Volltext

Therapy-Induced Senescence: Opportunities to Improve Anticancer Therapy von Prasanna, Pataje G, Citrin, Deborah E, Hildesheim, Jeffrey, Ahmed, Mansoor M, Venkatachalam, Sundar, Riscuta, Gabriela, Xi, Dan, Zheng, Guangrong, Deursen, Jan van, Goronzy, Jorg, Kron, Stephen J, Anscher, Mitchell S, Sharpless, Norman E, Campisi, Judith, Brown, Stephen L, Niedernhofer, Laura J, O’Loghlen, Ana, Georgakilas, Alexandros G, Paris, Francois, Gius, David, Gewirtz, David A, Schmitt, Clemens A, Abazeed, Mohamed E, Kirkland, James L, Richmond, Ann, Romesser, Paul B, Lowe, Scott W, Gil, Jesus, Mendonca, Marc S, Burma, Sandeep, Zhou, Daohong, Coleman, C Norman

Volltext

Discovery of piperlongumine as a potential novel lead for the development of senolytic agents von Wang, Yingying, Chang, Jianhui, Liu, Xingui, Zhang, Xuan, Zhang, Suping, Zhang, Xin, Zhou, Daohong, Zheng, Guangrong

Volltext

IL-17 and immunologically induced senescence regulate response to injury in osteoarthritis von Faust, Heather J., Zhang, Hong, Han, Jin, Wolf, Matthew T., Jeon, Ok Hee, Sadtler, Kaitlyn, Pena, Alexis N., Chung, Liam, Maestas, David R., Tam, Ada J., Pardoll, Drew M., Campisi, Judith, Housseau, Franck, Zhou, Daohong, Bingham, Clifton O., Elisseeff, Jennifer H.

Volltext

Using proteolysis-targeting chimera technology to reduce navitoclax platelet toxicity and improve its senolytic activity von He, Yonghan, Zhang, Xuan, Chang, Jianhui, Kim, Ha-Neui, Zhang, Peiyi, Wang, Yingying, Khan, Sajid, Liu, Xingui, Zhang, Xin, Lv, Dongwen, Song, Lin, Li, Wen, Thummuri, Dinesh, Yuan, Yaxia, Wiegand, Janet S., Ortiz, Yuma T., Budamagunta, Vivekananda, Elisseeff, Jennifer H., Campisi, Judith, Almeida, Maria, Zheng, Guangrong, Zhou, Daohong

Volltext

MicroRNA Regulation of Ionizing Radiation-Induced Premature Senescence von Wang, Yong, M.D., Ph.D, Scheiber, Melissa N., B.S, Neumann, Carola, Ph.D, Calin, George A., Ph.D, Zhou, Daohong, M.D

Volltext

Inhibition of Bcl-2/xl with ABT-263 selectively kills senescent Type II pneumocytes and reverses persistent pulmonary fibrosis induced by ionizing radiation in mice von Pan, Jin, PhD, Li, Deguan, PhD, Xu, Yanfeng, PhD, Zhang, Junling, PhD, Wang, Yueying, BS, Chen, Mengyi, MS, Lin, Shuai, MS, Huang, Lan, BS, Chung, Eun Joo, PhD, Citrin, Deborah E., MD, Wang, Yingying, PhD, Hauer-Jensen, Martin, MD & PhD, Zhou, Daohong, MD, Meng, Aimin, MD

Volltext

Development of a BCL-xL and BCL-2 dual degrader with improved anti-leukemic activity von Lv, Dongwen, Pal, Pratik, Liu, Xingui, Jia, Yannan, Thummuri, Dinesh, Zhang, Peiyi, Hu, Wanyi, Pei, Jing, Zhang, Qi, Zhou, Shuo, Khan, Sajid, Zhang, Xuan, Hua, Nan, Yang, Qingping, Arango, Sebastian, Zhang, Weizhou, Nayak, Digant, Olsen, Shaun K., Weintraub, Susan T., Hromas, Robert, Konopleva, Marina, Yuan, Yaxia, Zheng, Guangrong, Zhou, Daohong

Volltext

Inhibition of USP7 activity selectively eliminates senescent cells in part via restoration of p53 activity von He, Yonghan, Li, Wen, Lv, Dongwen, Zhang, Xin, Zhang, Xuan, Ortiz, Yuma T., Budamagunta, Vivekananda, Campisi, Judith, Zheng, Guangrong, Zhou, Daohong

Volltext

Oxidation resistance 1 is a novel senolytic target von Zhang, Xin, Zhang, Suping, Liu, Xingui, Wang, Yingying, Chang, Jianhui, Zhang, Xuan, Mackintosh, Samuel G., Tackett, Alan J., He, Yonghan, Lv, Dongwen, Laberge, Remi‐Martin, Campisi, Judith, Wang, Jianrong, Zheng, Guangrong, Zhou, Daohong

Volltext

Metformin ameliorates ionizing irradiation-induced long-term hematopoietic stem cell injury in mice von Xu, Guoshun, Wu, Hongying, Zhang, Junling, Li, Deguan, Wang, Yueying, Wang, Yingying, Zhang, Heng, Lu, Lu, Li, Chengcheng, Huang, Song, Xing, Yonghua, Zhou, Daohong, Meng, Aimin

Volltext

Proteolysis targeting chimeras (PROTACs) are emerging therapeutics for hematologic malignancies von He, Yonghan, Khan, Sajid, Huo, Zhiguang, Lv, Dongwen, Zhang, Xuan, Liu, Xingui, Yuan, Yaxia, Hromas, Robert, Xu, Mingjiang, Zheng, Guangrong, Zhou, Daohong

Volltext

Total body irradiation causes residual bone marrow injury by induction of persistent oxidative stress in murine hematopoietic stem cells von Wang, Yong, Liu, Lingbo, Pazhanisamy, Senthil K., Li, Hongliang, Meng, Aimin, Zhou, Daohong

Volltext

Inter-Strain Differences in LINE-1 DNA Methylation in the Mouse Hematopoietic System in Response to Exposure to Ionizing Radiation von Miousse, Isabelle R, Chang, Jianhui, Shao, Lijian, Pathak, Rupak, Nzabarushimana, Étienne, Kutanzi, Kristy R, Landes, Reid D, Tackett, Alan J, Hauer-Jensen, Martin, Zhou, Daohong, Koturbash, Igor

Volltext

Total body irradiation causes long-term mouse BM injury via induction of HSC premature senescence in an Ink4a- and Arf-independent manner von Shao, Lijian, Feng, Wei, Li, Hongliang, Gardner, David, Luo, Yi, Wang, Yong, Liu, Lingbo, Meng, Aimin, Sharpless, Norman E., Zhou, Daohong

Volltext

CD177 modulates the function and homeostasis of tumor-infiltrating regulatory T cells von Kim, Myung-Chul, Borcherding, Nicholas, Ahmed, Kawther K., Voigt, Andrew P., Vishwakarma, Ajaykumar, Kolb, Ryan, Kluz, Paige N., Pandey, Gaurav, De, Umasankar, Drashansky, Theodore, Helm, Eric Y., Zhang, Xin, Gibson-Corley, Katherine N., Klesney-Tait, Julia, Zhu, Yuwen, Lu, Jinglu, Lu, Jinsong, Huang, Xian, Xiang, Hongrui, Cheng, Jinke, Wang, Dongyang, Wang, Zheng, Tang, Jian, Hu, Jiajia, Wang, Zhengting, Liu, Hua, Li, Mingjia, Zhuang, Haoyang, Avram, Dorina, Zhou, Daohong, Bacher, Rhonda, Zheng, Song Guo, Wu, Xuefeng, Zakharia, Yousef, Zhang, Weizhou

Volltext