Therapeutic Targeting of Oncogenic Tyrosine Phosphatases von Frankson, Rochelle, Yu, Zhi-Hong, Bai, Yunpeng, Li, Qinglin, Zhang, Ruo-Yu, Zhang, Zhong-Yin

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Regulatory Mechanisms and Novel Therapeutic Targeting Strategies for Protein Tyrosine Phosphatases von Yu, Zhi-Hong, Zhang, Zhong-Yin

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Protein tyrosine phosphatases as potential therapeutic targets von He, Rong-jun, Yu, Zhi-hong, Zhang, Ruo-yu, Zhang, Zhong-yin

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Drugging Protein Tyrosine Phosphatases through Targeted Protein Degradation von Miao, Jinmin, Zhang, Zhong-Yin

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PTPN2 phosphatase deletion in T cells promotes anti‐tumour immunity and CAR T‐cell efficacy in solid tumours von Wiede, Florian, Lu, Kun‐Hui, Du, Xin, Liang, Shuwei, Hochheiser, Katharina, Dodd, Garron T, Goh, Pei K, Kearney, Conor, Meyran, Deborah, Beavis, Paul A, Henderson, Melissa A, Park, Simone L, Waithman, Jason, Zhang, Sheng, Zhang, Zhong‐Yin, Oliaro, Jane, Gebhardt, Thomas, Darcy, Phillip K, Tiganis, Tony

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Protein Tyrosine Phosphatases in Hypothalamic Insulin and Leptin Signaling von Zhang, Zhong-Yin, Dodd, Garron T, Tiganis, Tony

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Protein tyrosine phosphatases as emerging targets for cancer immunotherapy von Qu, Zihan, Dong, Jiajun, Zhang, Zhong-Yin

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Small Molecule Degraders of Protein Tyrosine Phosphatase 1B and T‐Cell Protein Tyrosine Phosphatase for Cancer Immunotherapy von Dong, Jiajun, Miao, Jinmin, Miao, Yiming, Qu, Zihan, Zhang, Sheng, Zhu, Peipei, Wiede, Florian, Jassim, Brenson A., Bai, Yunpeng, Nguyen, Quyen, Lin, Jianping, Chen, Lan, Tiganis, Tony, Tao, W. Andy, Zhang, Zhong‐Yin

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SHP2 is a multifunctional therapeutic target in drug resistant metastatic breast cancer von Chen, Hao, Libring, Sarah, Ruddraraju, Kasi Viswanatharaju, Miao, Jinmin, Solorio, Luis, Zhang, Zhong-Yin, Wendt, Michael K.

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Phase Separation of Disease-Associated SHP2 Mutants Underlies MAPK Hyperactivation von Zhu, Guangya, Xie, Jingjing, Kong, Wenna, Xie, Jingfei, Li, Yichen, Du, Lin, Zheng, Qiangang, Sun, Lin, Guan, Mingfeng, Li, Huan, Zhu, Tianxin, He, Hao, Liu, Zhenying, Xia, Xi, Kan, Chen, Tao, Youqi, Shen, Hong C., Li, Dan, Wang, Siying, Yu, Yongguo, Yu, Zhi-Hong, Zhang, Zhong-Yin, Liu, Cong, Zhu, Jidong

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Small molecule tools for functional interrogation of protein tyrosine phosphatases von He, Rongjun, Zeng, Li‐Fan, He, Yantao, Zhang, Sheng, Zhang, Zhong‐Yin

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Negative regulation of TLR signaling in myeloid cells-implications for autoimmune diseases von Hamerman, Jessica A., Pottle, Jessica, Ni, Minjian, He, Yantao, Zhang, Zhong-Yin, Buckner, Jane H.

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Drugging the Undruggable: Therapeutic Potential of Targeting Protein Tyrosine Phosphatases von Zhang, Zhong-Yin

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The tyrosine phosphatase SHP2 controls TGFβ-induced STAT3 signaling to regulate fibroblast activation and fibrosis von Zehender, Ariella, Huang, Jingang, Györfi, Andrea-Hermina, Matei, Alexandru-Emil, Trinh-Minh, Thuong, Xu, Xiaohan, Li, Yi-Nan, Chen, Chih-Wei, Lin, Jianping, Dees, Clara, Beyer, Christian, Gelse, Kolja, Zhang, Zhong-Yin, Bergmann, Christina, Ramming, Andreas, Birchmeier, Walter, Distler, Oliver, Schett, Georg, Distler, Jörg H. W.

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Inhibition of SHP2-mediated dephosphorylation of Ras suppresses oncogenesis von Bunda, Severa, Burrell, Kelly, Heir, Pardeep, Zeng, Lifan, Alamsahebpour, Amir, Kano, Yoshihito, Raught, Brian, Zhang, Zhong-Yin, Zadeh, Gelareh, Ohh, Michael

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Quinic Acid‐Conjugated Nanoparticles Enhance Drug Delivery to Solid Tumors via Interactions with Endothelial Selectins von Xu, Jun, Lee, Steve Seung‐Young, Seo, Howon, Pang, Liang, Jun, Yearin, Zhang, Ruo‐Yu, Zhang, Zhong‐Yin, Kim, Pilhan, Lee, Wooin, Kron, Stephen J., Yeo, Yoon

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Tyrosyl phosphorylation of KRAS stalls GTPase cycle via alteration of switch I and II conformation von Kano, Yoshihito, Gebregiworgis, Teklab, Marshall, Christopher B., Radulovich, Nikolina, Poon, Betty P. K., St-Germain, Jonathan, Cook, Jonathan D., Valencia-Sama, Ivette, Grant, Benjamin M. M., Herrera, Silvia Gabriela, Miao, Jinmin, Raught, Brian, Irwin, Meredith S., Lee, Jeffrey E., Yeh, Jen Jen, Zhang, Zhong-Yin, Tsao, Ming-Sound, Ikura, Mitsuhiko, Ohh, Michael

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Discovery of a SHP2 Degrader with In Vivo Anti-Tumor Activity von Miao, Jinmin, Bai, Yunpeng, Miao, Yiming, Qu, Zihan, Dong, Jiajun, Zhang, Ruo-Yu, Aggarwal, Devesh, Jassim, Brenson A, Nguyen, Quyen, Zhang, Zhong-Yin

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Insulin regulates POMC neuronal plasticity to control glucose metabolism von Dodd, Garron T, Michael, Natalie J, Lee-Young, Robert S, Mangiafico, Salvatore P, Pryor, Jack T, Munder, Astrid C, Simonds, Stephanie E, Brüning, Jens Claus, Zhang, Zhong-Yin, Cowley, Michael A, Andrikopoulos, Sofianos, Horvath, Tamas L, Spanswick, David, Tiganis, Tony

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Protein tyrosine phosphatases: structure and function, substrate specificity, and inhibitor development von Zhang, Zhong-Yin

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