Targeted protein degradation: mechanisms, strategies and application von Zhao, Lin, Zhao, Jia, Zhong, Kunhong, Tong, Aiping, Jia, Da

Volltext

Tumor-associated microglia and macrophages in glioblastoma: From basic insights to therapeutic opportunities von Wang, Guoqing, Zhong, Kunhong, Wang, Zeng, Zhang, Zongliang, Tang, Xin, Tong, Aiping, Zhou, Liangxue

Volltext

Development of multivalent nanobodies blocking SARS-CoV-2 infection by targeting RBD of spike protein von Lu, Qizhong, Zhang, Zongliang, Li, Hexian, Zhong, Kunhong, Zhao, Qin, Wang, Zeng, Wu, Zhiguo, Yang, Donghui, Sun, Shuang, Yang, Nian, Zheng, Meijun, Chen, Qiang, Long, Cheng, Guo, Wenhao, Yang, Hui, Nie, Chunlai, Tong, Aiping

Volltext

Long non-coding RNA SPRY4-IT1 promotes cell proliferation and invasion by regulation of Cdc20 in pancreatic cancer cells von Guo, Wenhao, Zhong, Kunhong, Wei, Heng, Nie, Chunlai, Yuan, Zhu

Volltext

An Anti-CD7 Antibody-Drug Conjugate Target Showing Potent Antitumor Activity for T-Lymphoblastic Leukemia (T-ALL) von Wang, Shiqi, Zhang, Ruyuan, Zhong, Kunhong, Guo, Wenhao, Tong, Aiping

Volltext

B7-H3-Targeted CAR-T Cells Exhibit Potent Antitumor Effects on Hematologic and Solid Tumors von Zhang, Zongliang, Jiang, Caiying, Liu, Zhiyong, Yang, Meijia, Tang, Xin, Wang, Yuelong, Zheng, Meijun, Huang, Jianhan, Zhong, Kunhong, Zhao, Shasha, Tang, Mei, Zhou, Tingyue, Yang, Hui, Guo, Gang, Zhou, Liangxue, Xu, Jianguo, Tong, Aiping

Volltext

Lipid Nanoparticle Delivery System for mRNA Encoding B7H3‐redirected Bispecific Antibody Displays Potent Antitumor Effects on Malignant Tumors von Huang, Cheng, Duan, Xing, Wang, Jichao, Tian, Qingqing, Ren, Yangmei, Chen, Kepan, Zhang, Zongliang, Li, Yuanyou, Feng, Yunyu, Zhong, Kunhong, Wang, Yuelong, Zhou, Liangxue, Guo, Gang, Song, Xiangrong, Tong, Aiping

Volltext

A drug screening to identify novel combinatorial strategies for boosting cancer immunotherapy efficacy von Zhang, Zongliang, Wang, Guoqing, Zhong, Kunhong, Chen, Yongdong, Yang, Nian, Lu, Qizhong, Yuan, Boyang, Wang, Zeng, Li, Hexian, Guo, Liping, Zhang, Ruyuan, Wu, Zhiguo, Zheng, Meijun, Zhao, Shasha, Tang, Xin, Shao, Bin, Tong, Aiping

Volltext

Evaluating the predictive value of genetic risk score in colorectal cancer among Chinese Han population von Ye, Ding, Jiang, Danjie, Gu, Simeng, Mao, Yingying, Qian, Sangni, Lin, Shujuan, Li, Qilong, Yang, Jinhua, Zhong, Kunhong, Jin, Mingjuan, Chen, Kun

Volltext

SARS‐CoV‐2 spike protein harnesses SNX27‐mediated endocytic recycling pathway von Zhao, Lin, Zhong, Kunhong, Zhao, Jia, Yong, Xin, Tong, Aiping, Jia, Da

Volltext

Histones released by NETosis enhance the infectivity of SARS-CoV-2 by bridging the spike protein subunit 2 and sialic acid on host cells von Hong, Weiqi, Yang, Jingyun, Zou, Jun, Bi, Zhenfei, He, Cai, Lei, Hong, He, Xuemei, Li, Xue, Alu, Aqu, Ren, Wenyan, Wang, Zeng, Jiang, Xiaohua, Zhong, Kunhong, Jia, Guowen, Yang, Yun, Yu, Wenhai, Huang, Qing, Yang, Mengli, Zhou, Yanan, Zhao, Yuan, Kuang, Dexuan, Wang, Junbin, Wang, Haixuan, Chen, Siyuan, Luo, Min, Zhang, Ziqi, Lu, Tianqi, Chen, Li, Que, Haiying, He, Zhiyao, Sun, Qiu, Wang, Wei, Shen, Guobo, Lu, Guangwen, Zhao, Zhiwei, Yang, Li, Yang, Jinliang, Wang, Zhenling, Li, Jiong, Song, Xiangrong, Dai, Lunzhi, Chen, Chong, Geng, Jia, Gou, Maling, Chen, Lu, Dong, Haohao, Peng, Yong, Huang, Canhua, Qian, Zhiyong, Cheng, Wei, Fan, Changfa, Wei, Yuquan, Su, Zhaoming, Tong, Aiping, Lu, Shuaiyao, Peng, Xiaozhong, Wei, Xiawei

Volltext

Efficacy of B7-H3-Redirected BiTE and CAR-T Immunotherapies Against Extranodal Nasal Natural Killer/T Cell Lymphoma von Zheng, Meijun, Yu, Lingyu, Hu, Juanjuan, Zhang, Zongliang, Wang, Haiyang, Lu, Dan, Tang, Xin, Huang, Jianhan, Zhong, Kunhong, Wang, Zeng, Li, Yisong, Guo, Gang, Liu, Shixi, Tong, Aiping, Yang, Hui

Volltext

Fn14-targeted BiTE and CAR-T cells demonstrate potent preclinical activity against glioblastoma von Li, Gaowei, Zhang, Zongliang, Cai, Linjun, Tang, Xin, Huang, Jianhan, Yu, Lingyu, Wang, Guoqing, Zhong, Kunhong, Cao, Yi, Liu, Chang, Wang, Yuelong, Tong, Aiping, Zhou, Liangxue

Volltext

MEK Inhibitor Augments Antitumor Activity of B7-H3-Redirected Bispecific Antibody von Li, Hongjian, Huang, Cheng, Zhang, Zongliang, Feng, Yunyu, Wang, Zeng, Tang, Xin, Zhong, Kunhong, Hu, Yating, Guo, Gang, Zhou, Liangxue, Guo, Wenhao, Xu, Jianguo, Yang, Hui, Tong, Aiping

Volltext

Evaluation of B7-H3 Targeted Immunotherapy in a 3D Organoid Model of Craniopharyngioma von Tang, Mei, Chen, Caili, Wang, Guoqing, Wang, Yuelong, Zhang, Zongliang, Li, Hexian, Lu, Qizhong, Wang, Zeng, Zhao, Shasha, Yang, Chen, Zhong, Kunhong, Zhang, Ruyuan, Guo, Liping, Yuan, Zhu, Nie, Chunlai, Tong, Aiping

Volltext

Genome-scale CRISPR–Cas9 screen reveals novel regulators of B7-H3 in tumor cells von Zhao, Shasha, Wang, Yuelong, Yang, Nian, Mu, Min, Wu, Zhiguo, Li, Hexian, Tang, Xin, Zhong, Kunhong, Zhang, Zongliang, Huang, Cheng, Cao, Ting, Zheng, Meijun, Wang, Guoqing, Nie, Chunlai, Yang, Hui, Guo, Gang, Zhou, Liangxue, Zheng, Xi, Tong, Aiping

Volltext

AP-64, Encoded by C5orf46 , Exhibits Antimicrobial Activity against Gram-Negative Bacteria von Zhong, Kunhong, Wang, Yuelong, Wang, Zeng, Zhang, Zongliang, Zhao, Shasha, Li, Hexian, Huang, Jianhan, Guo, Wenhao, Zheng, Xi, Guo, Gang, Zhou, Liangxue, Yang, Hui, Tong, Aiping

Volltext

CXCL11-armed oncolytic adenoviruses enhance CAR-T cell therapeutic efficacy and reprogram tumor microenvironment in glioblastoma von Wang, Guoqing, Zhang, Zongliang, Zhong, Kunhong, Wang, Zeng, Yang, Nian, Tang, Xin, Li, Hexian, Lu, Qizhong, Wu, Zhiguo, Yuan, Boyang, Zheng, Meijun, Cheng, Ping, Tong, Aiping, Zhou, Liangxue

Volltext

Tandem CAR-T cells targeting CD70 and B7-H3 exhibit potent preclinical activity against multiple solid tumors von Yang, Meijia, Tang, Xin, Zhang, Zongliang, Gu, Lei, Wei, Heng, Zhao, Shasha, Zhong, Kunhong, Mu, Min, Huang, Cheng, Jiang, Caiying, Xu, Jianguo, Guo, Gang, Zhou, Liangxue, Tong, Aiping

Volltext

Systemic delivery of tannic acid-ferric-masked oncolytic adenovirus reprograms tumor microenvironment for improved therapeutic efficacy in glioblastoma von Wang, Guoqing, Mu, Min, Zhang, Zongliang, Chen, Yongdong, Yang, Nian, Zhong, Kunhong, Li, Yanfang, Lu, Fang, Guo, Gang, Tong, Aiping

Volltext