Rapid screening and characterization of glutathione-trapped reactive metabolites using a polarity switch-based approach on a high-resolution quadrupole orbitrap mass spectrometer von Wang, Zhican, Fang, Ying, Rock, Dan, Ma, Ji

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Development of a microphysiological model of human kidney proximal tubule function von Weber, Elijah J., Chapron, Alenka, Chapron, Brian D., Voellinger, Jenna L., Lidberg, Kevin A., Yeung, Catherine K., Wang, Zhican, Yamaura, Yoshiyuki, Hailey, Dale W., Neumann, Thomas, Shen, Danny D., Thummel, Kenneth E., Muczynski, Kimberly A., Himmelfarb, Jonathan, Kelly, Edward J.

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Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growth von Lee, Bianca J., Boyer, Jacob A., Burnett, G. Leslie, Thottumkara, Arun P., Tibrewal, Nidhi, Wilson, Stacy L., Hsieh, Tientien, Marquez, Abby, Lorenzana, Edward G., Evans, James W., Hulea, Laura, Kiss, Gert, Liu, Hui, Lee, Dong, Larsson, Ola, McLaughlan, Shannon, Topisirovic, Ivan, Wang, Zhengping, Wang, Zhican, Zhao, Yongyuan, Wildes, David, Aggen, James B., Singh, Mallika, Gill, Adrian L., Smith, Jacqueline A. M., Rosen, Neal

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Polymorphic Human Sulfotransferase 2A1 Mediates the Formation of 25-Hydroxyvitamin D3-3-O-Sulfate, a Major Circulating Vitamin D Metabolite in Humans von Wong, Timothy, Wang, Zhican, Chapron, Brian D., Suzuki, Mizuki, Claw, Katrina G., Gao, Chunying, Foti, Robert S., Prasad, Bhagwat, Chapron, Alenka, Calamia, Justina, Chaudhry, Amarjit, Schuetz, Erin G., Horst, Ronald L., Mao, Qingcheng, de Boer, Ian H., Thornton, Timothy A., Thummel, Kenneth E.

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Human UGT1A4 and UGT1A3 Conjugate 25-Hydroxyvitamin D3: Metabolite Structure, Kinetics, Inducibility, and Interindividual Variability von Wang, Zhican, Wong, Timothy, Hashizume, Takanori, Dickmann, Leslie Z, Scian, Michele, Koszewski, Nicholas J, Goff, Jesse P, Horst, Ronald L, Chaudhry, Amarjit S, Schuetz, Erin G, Thummel, Kenneth E

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Characterizing Antibody Cross-reactivity for Immunoaffinity Purification of Analytes prior to Multiplexed Liquid Chromatography― Tandem Mass Spectrometry von LAHA, Thomas J, STRATHMANN, Frederick G, ZHICAN WANG, DE BOER, Ian H, THUMMEL, Kenneth E, HOOFNAGLE, Andrew N

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Author Correction: Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growth von Lee, Bianca J., Boyer, Jacob A., Burnett, G. Leslie, Thottumkara, Arun P., Tibrewal, Nidhi, Wilson, Stacy L., Hsieh, Tientien, Marquez, Abby, Lorenzana, Edward G., Evans, James W., Hulea, Laura, Kiss, Gert, Liu, Hui, Lee, Dong, Larsson, Ola, McLaughlan, Shannon, Topisirovic, Ivan, Wang, Zhengping, Wang, Zhican, Zhao, Yongyuan, Wildes, David, Aggen, James B., Singh, Mallika, Gill, Adrian L., Smith, Jacqueline A. M., Rosen, Neal

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Author Correction: Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growth von Lee, Bianca J., Boyer, Jacob A., Burnett, G. Leslie, Thottumkara, Arun P., Tibrewal, Nidhi, Wilson, Stacy L., Hsieh, Tientien, Marquez, Abby, Lorenzana, Edward G., Evans, James W., Hulea, Laura, Kiss, Gert, Liu, Hui, Lee, Dong, Larsson, Ola, McLaughlan, Shannon, Topisirovic, Ivan, Wang, Zhengping, Wang, Zhican, Zhao, Yongyuan, Wildes, David, Aggen, James B., Singh, Mallika, Gill, Adrian L., Smith, Jacqueline A. M., Rosen, Neal

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An Inducible Cytochrome P450 3A4-Dependent Vitamin D Catabolic Pathway von Wang, Zhican, Lin, Yvonne S., Zheng, Xi Emily, Senn, Tauri, Hashizume, Takanori, Scian, Michele, Dickmann, Leslie J., Nelson, Sidney D., Baillie, Thomas A., Hebert, Mary F., Blough, David, Davis, Connie L., Thummel, Kenneth E.

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Enhancement of hepatic 4‐hydroxylation of 25‐hydroxyvitamin D3 through CYP3A4 induction in vitro and in vivo: Implications for drug‐induced osteomalacia von Wang, Zhican, Lin, Yvonne S, Dickmann, Leslie J, Poulton, Emma‐Jane, Eaton, David L, Lampe, Johanna W, Shen, Danny D, Davis, Connie L, Shuhart, Margaret C, Thummel, Kenneth E

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Estimated GFR and Circulating 24,25-Dihydroxyvitamin D3  Concentration: A Participant-Level Analysis of 5 Cohort Studies and Clinical Trials von de Boer, Ian H., MD, MS, Sachs, Michael C., PhD, Chonchol, Michel, MD, Himmelfarb, Jonathan, MD, Hoofnagle, Andrew N., MD, PhD, Ix, Joachim H., MD, MAS, Kremsdorf, Robin A., MD, MS, Lin, Yvonne S., PhD, Mehrotra, Rajnish, MD, Robinson-Cohen, Cassianne, PhD, Siscovick, David S., MD, MPH, Steffes, Michael W., MD, PhD, Thummel, Kenneth E., PhD, Tracy, Russell P., PhD, Wang, Zhican, PhD, Kestenbaum, Bryan, MD, MS

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COSA Plus: Enhanced Co-Operative Systolic Arrays for Attention Mechanism in Transformers von Wang, Zhican, Wang, Gang, He, Guanghui

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Redox Cycling of Catechol Estrogens Generating Apurinic/Apyrimidinic Sites and 8-oxo-Deoxyguanosine via Reactive Oxygen Species Differentiates Equine and Human Estrogens von Wang, Zhican, Chandrasena, Esala R, Yuan, Yang, Peng, Kuan-wei, van Breemen, Richard B, Thatcher, Gregory R. J, Bolton, Judy L

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An Energy Efficient Accelerator for Bidirectional Recurrent Neural Networks (BiRNNs) Using Hybrid-Iterative Compression With Error Sensitivity von Nan, Guocai, Wang, Zhengkuan, Wang, Chenghua, Wu, Bi, Wang, Zhican, Liu, Weiqiang, Lombardi, Fabrizio

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Interplay between vitamin D and the drug metabolizing enzyme CYP3A4 von Wang, Zhican, Schuetz, Erin G., Xu, Yang, Thummel, Kenneth E.

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Chemical remodeling of a cellular chaperone to target the active state of mutant KRAS von Schulze, Christopher J, Seamon, Kyle J, Zhao, Yulei, Yang, Yu C, Cregg, Jim, Kim, Dongsung, Tomlinson, Aidan, Choy, Tiffany J, Wang, Zhican, Sang, Ben, Pourfarjam, Yasin, Lucas, Jessica, Cuevas-Navarro, Antonio, Ayala-Santos, Carlos, Vides, Alberto, Li, Chuanchuan, Marquez, Abby, Zhong, Mengqi, Vemulapalli, Vidyasiri, Weller, Caroline, Gould, Andrea, Whalen, Daniel M, Salvador, Anthony, Milin, Anthony, Saldajeno-Concar, Mae, Dinglasan, Nuntana, Chen, Anqi, Evans, Jim, Knox, John E, Koltun, Elena S, Singh, Mallika, Nichols, Robert, Wildes, David, Gill, Adrian L, Smith, Jacqueline A M, Lito, Piro

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Vitamin D Metabolism Is Dysregulated in Asthma and Chronic Obstructive Pulmonary Disease von Jolliffe, David A, Stefanidis, Christos, Wang, Zhican, Kermani, Nazanin Z, Dimitrov, Vassil, White, John H, McDonough, John E, Janssens, Wim, Pfeffer, Paul, Griffiths, Christopher J, Bush, Andrew, Guo, Yike, Christenson, Stephanie, Adcock, Ian M, Chung, Kian Fan, Thummel, Kenneth E, Martineau, Adrian R

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Differential Effects of Oral Boluses of Vitamin D2 vs Vitamin D3 on Vitamin D Metabolism: A Randomized Controlled Trial von Martineau, Adrian R, Thummel, Kenneth E, Wang, Zhican, Jolliffe, David A, Boucher, Barbara J, Griffin, Simon J, Forouhi, Nita G, Hitman, Graham A

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Discovery of RMC-5552, a Selective Bi-Steric Inhibitor of mTORC1, for the Treatment of mTORC1-Activated Tumors von Burnett, G. Leslie, Yang, Yu C., Aggen, James B., Pitzen, Jennifer, Gliedt, Micah K., Semko, Chris M., Marquez, Abby, Evans, James W., Wang, Gang, Won, Walter S., Tomlinson, Aidan C. A., Kiss, Gert, Tzitzilonis, Christos, Thottumkara, Arun P., Cregg, James, Mellem, Kevin T., Choi, Jong S., Lee, Julie C., Zhao, Yongyuan, Lee, Bianca J., Meyerowitz, Justin G., Knox, John E., Jiang, Jingjing, Wang, Zhican, Wildes, David, Wang, Zhengping, Singh, Mallika, Smith, Jacqueline A. M., Gill, Adrian L.

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Functional Comparison of Human Colonic Carcinoma Cell Lines and Primary Small Intestinal Epithelial Cells for Investigations of Intestinal Drug Permeability and First-Pass Metaboli... von Yamaura, Yoshiyuki, Chapron, Brian D, Wang, Zhican, Himmelfarb, Jonathan, Thummel, Kenneth E

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