A Systematic Survey of Loss-of-Function Variants in Human Protein-Coding Genes von MacArthur, Daniel G., Balasubramanian, Suganthi, Frankish, Adam, Huang, Ni, Morris, James, Walter, Klaudia, Jostins, Luke, Habegger, Lukas, Pickrell, Joseph K., Montgomery, Stephen B., Albers, Cornelis A., Zhang, Zhengdong D., Conrad, Donald F., Lunter, Gerton, Zheng, Hancheng, Ayub, Qasim, DePristo, Mark A., Banks, Eric, Hu, Min, Handsaker, Robert E., Rosenfeld, Jeffrey A., Fromer, Menachem, Jin, Mike, Mu, Xinmeng Jasmine, Khurana, Ekta, Ye, Kai, Kay, Mike, Saunders, Gary Ian, Suner, Marie-Marthe, Hunt, Toby, Barnes, H. A., Amid, Clara, Carvalho-Silva, Denise R., Bignell, Alexandra H., Snow, Catherine, Yngvadottir, Bryndis, Bumpstead, Suzannah, Cooper, David N., Xue, Yali, Romero, Irene Gallego, Wang, Jun, Li, Yingrui, Gibbs, Richard A., McCarroll, Steven A., Dermitzakis, Emmanouil T., Pritchard, Jonathan K., Barrett, Jeffrey C., Harrow, Jennifer, Hurles, Matthew E., Gerstein, Mark B., Tyler-Smith, Chris

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Sequencing of 50 Human Exomes Reveals Adaptation to High Altitude von Yi, Xin, Liang, Yu, Huerta-Sanchez, Emilia, Jin, Xin, Cuo, Zha Xi Ping, Pool, John E, Xu, Xun, Jiang, Hui, Vinckenbosch, Nicolas, Korneliussen, Thorfinn Sand, Zheng, Hancheng, Liu, Tao, He, Weiming, Li, Kui, Luo, Ruibang, Nie, Xifang, Wu, Honglong, Zhao, Meiru, Cao, Hongzhi, Zou, Jing, Shan, Ying, Li, Shuzheng, Yang, Qi, Asan, Ni, Peixiang, Tian, Geng, Xu, Junming, Liu, Xiao, Jiang, Tao, Wu, Renhua, Zhou, Guangyu, Tang, Meifang, Qin, Junjie, Wang, Tong, Feng, Shuijian, Li, Guohong, Huasang, Luosang, Jiangbai, Wang, Wei, Chen, Fang, Wang, Yading, Zheng, Xiaoguang, Li, Zhuo, Bianba, Zhuoma, Yang, Ge, Wang, Xinping, Tang, Shuhui, Gao, Guoyi, Chen, Yong, Luo, Zhen, Gusang, Lamu, Cao, Zheng, Zhang, Qinghui, Ouyang, Weihan, Ren, Xiaoli, Liang, Huiqing, Zheng, Huisong, Huang, Yebo, Li, Jingxiang, Bolund, Lars, Kristiansen, Karsten, Li, Yingrui, Zhang, Yong, Zhang, Xiuqing, Li, Ruiqiang, Li, Songgang, Yang, Huanming, Nielsen, Rasmus, Wang, Jun, Wang, Jian

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Whole-Genome Sequencing in Autism Identifies Hot Spots for De Novo Germline Mutation von Michaelson, Jacob J., Shi, Yujian, Gujral, Madhusudan, Zheng, Hancheng, Malhotra, Dheeraj, Jin, Xin, Jian, Minghan, Liu, Guangming, Greer, Douglas, Bhandari, Abhishek, Wu, Wenting, Corominas, Roser, Peoples, Áine, Koren, Amnon, Gore, Athurva, Kang, Shuli, Lin, Guan Ning, Estabillo, Jasper, Gadomski, Therese, Singh, Balvindar, Zhang, Kun, Akshoomoff, Natacha, Corsello, Christina, McCarroll, Steven, Iakoucheva, Lilia M., Li, Yingrui, Wang, Jun, Sebat, Jonathan

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Whole-genome sequencing identifies recurrent mutations in hepatocellular carcinoma von Kan, Zhengyan, Zheng, Hancheng, Liu, Xiao, Li, Shuyu, Barber, Thomas D, Gong, Zhuolin, Gao, Huan, Hao, Ke, Willard, Melinda D, Xu, Jiangchun, Hauptschein, Robert, Rejto, Paul A, Fernandez, Julio, Wang, Guan, Zhang, Qinghui, Wang, Bo, Chen, Ronghua, Wang, Jian, Lee, Nikki P, Zhou, Wei, Lin, Zhao, Peng, Zhiyu, Yi, Kang, Chen, Shengpei, Li, Lin, Fan, Xiaomei, Yang, Jie, Ye, Rui, Ju, Jia, Wang, Kai, Estrella, Heather, Deng, Shibing, Wei, Ping, Qiu, Ming, Wulur, Isabella H, Liu, Jiangang, Ehsani, Mariam E, Zhang, Chunsheng, Loboda, Andrey, Sung, Wing Kin, Aggarwal, Amit, Poon, Ronnie T, Fan, Sheung Tat, Wang, Jun, Hardwick, James, Reinhard, Christoph, Dai, Hongyue, Li, Yingrui, Luk, John M, Mao, Mao

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Single-Cell Exome Sequencing and Monoclonal Evolution of a JAK2-Negative Myeloproliferative Neoplasm von Hou, Yong, Song, Luting, Zhu, Ping, Zhang, Bo, Tao, Ye, Xu, Xun, Li, Fuqiang, Wu, Kui, Liang, Jie, Shao, Di, Wu, Hanjie, Ye, Xiaofei, Ye, Chen, Wu, Renhua, Jian, Min, Chen, Yan, Xie, Wei, Zhang, Ruren, Chen, Lei, Liu, Xin, Yao, Xiaotian, Zheng, Hancheng, Yu, Chang, Li, Qibin, Gong, Zhuolin, Mao, Mao, Yang, Xu, Yang, Lin, Li, Jingxiang, Wang, Wen, Lu, Zuhong, Gu, Ning, Laurie, Goodman, Bolund, Lars, Kristiansen, Karsten, Wang, Jian, Yang, Huanming, Li, Yingrui, Zhang, Xiuqing, Wang, Jun

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Historical variations in mutation rate in an epidemic pathogen, Yersinia pestis von Cui, Yujun, Yu, Chang, Yan, Yanfeng, Li, Dongfang, Li, Yanjun, Jombart, Thibaut, Weinert, Lucy A., Wang, Zuyun, Guo, Zhaobiao, Xu, Lizhi, Zhang, Yujiang, Zheng, Hancheng, Qin, Nan, Xiao, Xiao, Wu, Mingshou, Wang, Xiaoyi, Zhou, Dongsheng, Qi, Zhizhen, Du, Zongmin, Wu, Honglong, Yang, Xianwei, Cao, Hongzhi, Wang, Hu, Wang, Jing, Yao, Shusen, Rakin, Alexander, Li, Yingrui, Falush, Daniel, Balloux, Francois, Achtman, Mark, Song, Yajun, Wang, Jun, Yang, Ruifu

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Whole-genome and Transcriptome Sequencing of Prostate Cancer Identify New Genetic Alterations Driving Disease Progression von Ren, Shancheng, Wei, Gong-Hong, Liu, Dongbing, Wang, Liguo, Hou, Yong, Zhu, Shida, Peng, Lihua, Zhang, Qin, Cheng, Yanbing, Su, Hong, Zhou, Xiuqing, Zhang, Jibin, Li, Fuqiang, Zheng, Hancheng, Zhao, Zhikun, Yin, Changjun, He, Zengquan, Gao, Xin, Zhau, Haiyen E., Chu, Chia-Yi, Wu, Jason Boyang, Collins, Colin, Volik, Stanislav V., Bell, Robert, Huang, Jiaoti, Wu, Kui, Xu, Danfeng, Ye, Dingwei, Yu, Yongwei, Zhu, Lianhui, Qiao, Meng, Lee, Hang-Mao, Yang, Yuehong, Zhu, Yasheng, Shi, Xiaolei, Chen, Rui, Wang, Yang, Xu, Weidong, Cheng, Yanqiong, Xu, Chuanliang, Gao, Xu, Zhou, Tie, Yang, Bo, Hou, Jianguo, Liu, Li, Zhang, Zhensheng, Zhu, Yao, Qin, Chao, Shao, Pengfei, Pang, Jun, Chung, Leland W.K., Xu, Jianfeng, Wu, Chin-Lee, Zhong, Weide, Xu, Xun, Li, Yingrui, Zhang, Xiuqing, Wang, Jian, Yang, Huanming, Wang, Jun, Huang, Haojie, Sun, Yinghao

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Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder von Yang, Huanming, Wang, Jun, Cai, Zhiming, Gui, Yaoting, Guo, Guangwu, Huang, Yi, Hu, Xueda, Tang, Aifa, Gao, Shengjie, Wu, Renhua, Chen, Chao, Li, Xianxin, Zhou, Liang, He, Minghui, Li, Zesong, Sun, Xiaojuan, Jia, Wenlong, Chen, Jinnong, Yang, Shangming, Zhou, Fangjian, Zhao, Xiaokun, Wan, Shengqing, Ye, Rui, Liang, Chaozhao, Liu, Zhisheng, Huang, Peide, Liu, Chunxiao, Jiang, Hui, Wang, Yong, Zheng, Hancheng, Sun, Liang, Liu, Xingwang, Jiang, Zhimao, Feng, Dafei, Chen, Jing, Wu, Song, Zou, Jing, Zhang, Zhongfu, Yang, Ruilin, Zhao, Jun, Xu, Congjie, Yin, Weihua, Guan, Zhichen, Ye, Jiongxian, Zhang, Hong, Li, Jingxiang, Kristiansen, Karsten, Nickerson, Michael L, Theodorescu, Dan, Li, Yingrui, Zhang, Xiuqing, Li, Songgang, Wang, Jian

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The DNA methylome of human peripheral blood mononuclear cells von Li, Yingrui, Zhu, Jingde, Tian, Geng, Li, Ning, Li, Qibin, Ye, Mingzhi, Zheng, Hancheng, Yu, Jian, Wu, Honglong, Sun, Jihua, Zhang, Hongyu, Chen, Quan, Luo, Ruibang, Chen, Minfeng, He, Yinghua, Jin, Xin, Zhang, Qinghui, Yu, Chang, Zhou, Guangyu, Sun, Jinfeng, Huang, Yebo, Zheng, Huisong, Cao, Hongzhi, Zhou, Xiaoyu, Guo, Shicheng, Hu, Xueda, Li, Xin, Kristiansen, Karsten, Bolund, Lars, Xu, Jiujin, Wang, Wen, Yang, Huanming, Wang, Jian, Li, Ruiqiang, Beck, Stephan, Wang, Jun, Zhang, Xiuqing

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Comprehensive Characterization of Oncogenic Drivers in Asian Lung Adenocarcinoma von Li, Shiyong, Choi, Yoon-La, Gong, Zhuolin, Liu, Xiao, Lira, Maruja, Kan, Zhengyan, Oh, Ensel, Wang, Jian, Ting, Jason C., Ye, Xiangsheng, Reinhart, Christoph, Liu, Xiaoqiao, Pei, Yunfei, Zhou, Wei, Chen, Ronghua, Fu, Shijun, Jin, Gang, Jiang, Awei, Fernandez, Julio, Hardwick, James, Kang, Min Woong, I, Hoseok, Zheng, Hancheng, Kim, Jhingook, Mao, Mao

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Exome sequencing identifies ZNF644 mutations in high myopia von Shi, Yi, Li, Yingrui, Zhang, Dingding, Zhang, Hao, Li, Yuanfeng, Lu, Fang, Liu, Xiaoqi, He, Fei, Gong, Bo, Cai, Li, Li, Ruiqiang, Liao, Shihuang, Ma, Shi, Lin, He, Cheng, Jing, Zheng, Hancheng, Shan, Ying, Chen, Bin, Hu, Jianbin, Jin, Xin, Zhao, Peiquan, Chen, Yiye, Zhang, Yong, Lin, Ying, Li, Xi, Fan, Yingchuan, Yang, Huanming, Wang, Jun, Yang, Zhenglin

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Discovery of biclonal origin and a novel oncogene SLC12A5 in colon cancer by single-cell sequencing von Yu, Chang, Yu, Jun, Yao, Xiaotian, Wu, William KK, Lu, Youyong, Tang, Senwei, Li, Xiangchun, Bao, Li, Li, Xiaoxing, Hou, Yong, Wu, Renhua, Jian, Min, Chen, Ruoyan, Zhang, Fan, Xu, Lixia, Fan, Fan, He, Jun, Liang, Qiaoyi, Wang, Hongyi, Hu, Xueda, He, Minghui, Zhang, Xiang, Zheng, Hancheng, Li, Qibin, Wu, Hanjie, Chen, Yan, Yang, Xu, Zhu, Shida, Xu, Xun, Yang, Huanming, Wang, Jian, Zhang, Xiuqing, Sung, Joseph JY, Li, Yingrui, Wang, Jun

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Building the sequence map of the human pan-genome von Zhu, Hongmei, Tian, Geng, Hu, Xueda, Li, Qibin, Cao, Hongzhi, Wang, Jian, Qian, Wubin, Bolund, Lars, Wu, Honglong, Li, Songgang, Li, Ruiqiang, Qin, Junjie, Kristiansen, Karsten, Li, Yingrui, Cann, Howard, Yang, Huanming, Wang, Jun, Zhu, Xuan, Zhang, Xiuqing, Jin, Xin, Blanche, Hélène, Luo, Ruibang, Ren, Yuanyuan, Li, Jinxiang, Zheng, Hancheng, Li, Dongfang, Zhou, Guangyu

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Sequence investigation of 34 forensic autosomal STRs with massively parallel sequencing von Zhang, Suhua, Niu, Yong, Bian, Yingnan, Dong, Rixia, Liu, Xiling, Bao, Yun, Jin, Chao, Zheng, Hancheng, Li, Chengtao

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Structural variation in two human genomes mapped at single-nucleotide resolution by whole genome de novo assembly von Wang, Jun, Li, Yingrui, Zheng, Hancheng, Luo, Ruibang, Wu, Honglong, Zhu, Hongmei, Li, Ruiqiang, Cao, Hongzhi, Wu, Boxin, Huang, Shujia, Shao, Haojing, Ma, Hanzhou, Zhang, Fan, Feng, Shuijian, Zhang, Wei, Du, Hongli, Tian, Geng, Li, Jingxiang, Zhang, Xiuqing, Li, Songgang, Bolund, Lars, Kristiansen, Karsten, de Smith, Adam J, Blakemore, Alexandra I F, Coin, Lachlan J M, Yang, Huanming, Wang, Jian

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Extensive X-linked adaptive evolution in central chimpanzees von Hvilsom, Christina, Qian, Yu, Bataillon, Thomas, Li, Yingrui, Mailund, Thomas, Sallé, Bettina, Carlsen, Frands, Li, Ruiqiang, Zheng, Hancheng, Jiang, Tao, Jiang, Hui, Jin, Xin, Munch, Kasper, Hobolth, Asger, Siegismund, Hans R, Wang, Jun, Schierup, Mikkel Heide

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Performance comparison between rapid sequencing platforms for ultra-low coverage sequencing strategy von Chen, Shengpei, Li, Sheng, Xie, Weiwei, Li, Xuchao, Zhang, Chunlei, Jiang, Haojun, Zheng, Jing, Pan, Xiaoyu, Zheng, Hancheng, Liu, Jia Sophie, Deng, Yongqiang, Chen, Fang, Jiang, Hui

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Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants von Pedersen, Oluf, Nielsen, Rasmus, Wang, Jun, Li, Yingrui, Vinckenbosch, Nicolas, Tian, Geng, Huerta-Sanchez, Emilia, Jiang, Tao, Jiang, Hui, Albrechtsen, Anders, Andersen, Gitte, Cao, Hongzhi, Korneliussen, Thorfinn, Grarup, Niels, Guo, Yiran, Hellman, Ines, Jin, Xin, Li, Qibin, Liu, Jiangtao, Liu, Xiao, Sparsø, Thomas, Tang, Meifang, Wu, Honglong, Wu, Renhua, Yu, Chang, Zheng, Hancheng, Astrup, Arne, Bolund, Lars, Holmkvist, Johan, Jørgensen, Torben, Kristiansen, Karsten, Schmitz, Ole, Schwartz, Thue W, Zhang, Xiuqing, Li, Ruiqiang, Yang, Huanming, Wang, Jian, Hansen, Torben

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Whole-genome sequencing of matched primary and metastatic hepatocellular carcinomas von Ouyang, Limei, Lee, Jeeyun, Park, Cheol-Keun, Mao, Mao, Shi, Yujian, Gong, Zhuolin, Zheng, Hancheng, Li, Yingrui, Zhao, Yonggang, Wang, Guangbiao, Fu, Huiling, Kim, Jhingook, Lim, Ho Yeong

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Single-cell sequencing analysis characterizes common and cell-lineage-specific mutations in a muscle-invasive bladder cancer von Li, Yingrui, Xu, Xun, Song, Luting, Hou, Yong, Li, Zesong, Tsang, Shirley, Li, Fuqiang, Im, Kate McGee, Wu, Kui, Wu, Hanjie, Ye, Xiaofei, Li, Guibo, Wang, Linlin, Zhang, Bo, Liang, Jie, Xie, Wei, Wu, Renhua, Jiang, Hui, Liu, Xiao, Yu, Chang, Zheng, Hancheng, Jian, Min, Nie, Liping, Wan, Lei, Shi, Min, Sun, Xiaojuan, Tang, Aifa, Guo, Guangwu, Gui, Yaoting, Cai, Zhiming, Li, Jingxiang, Wang, Wen, Lu, Zuhong, Zhang, Xiuqing, Bolund, Lars, Kristiansen, Karsten, Wang, Jian, Yang, Huanming, Dean, Michael, Wang, Jun

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