Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy von Wang, Chao, Fan, Li, Khawaja, Rabia R., Liu, Bangyan, Zhan, Lihong, Kodama, Lay, Chin, Marcus, Li, Yaqiao, Le, David, Zhou, Yungui, Condello, Carlo, Grinberg, Lea T., Seeley, William W., Miller, Bruce L., Mok, Sue-Ann, Gestwicki, Jason E., Cuervo, Ana Maria, Luo, Wenjie, Gan, Li

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Microglial microRNAs mediate sex-specific responses to tau pathology von Kodama, Lay, Guzman, Elmer, Etchegaray, Jon I., Li, Yaqiao, Sayed, Faten A., Zhou, Lu, Zhou, Yungui, Zhan, Lihong, Le, David, Udeochu, Joe C., Clelland, Claire D., Cheng, Zuolin, Yu, Guoqiang, Li, Qingyun, Kosik, Kenneth S., Gan, Li

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A CRISPRi/a platform in human iPSC-derived microglia uncovers regulators of disease states von Dräger, Nina M., Sattler, Sydney M., Huang, Cindy Tzu-Ling, Teter, Olivia M., Leng, Kun, Hashemi, Sayed Hadi, Hong, Jason, Aviles, Giovanni, Clelland, Claire D., Zhan, Lihong, Udeochu, Joe C., Kodama, Lay, Singleton, Andrew B., Nalls, Mike A., Ichida, Justin, Ward, Michael E., Faghri, Faraz, Gan, Li, Kampmann, Martin

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Differential effects of partial and complete loss of TREM2 on microglial injury response and tauopathy von Sayed, Faten A., Telpoukhovskaia, Maria, Kodama, Lay, Li, Yaqiao, Zhou, Yungui, Le, David, Hauduc, Axel, Ludwig, Connor, Gao, Fuying, Clelland, Claire, Zhan, Lihong, Cooper, Yonatan A., Davalos, Dimitrios, Akassoglou, Katerina, Coppola, Giovanni, Gan, Li

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Proximal recolonization by self-renewing microglia re-establishes microglial homeostasis in the adult mouse brain von Zhan, Lihong, Krabbe, Grietje, Du, Fei, Jones, Ian, Reichert, Meredith C, Telpoukhovskaia, Maria, Kodama, Lay, Wang, Chao, Cho, Seo-Hyun, Sayed, Faten, Li, Yaqiao, Le, David, Zhou, Yungui, Shen, Yin, West, Brian, Gan, Li

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A MAC2-positive progenitor-like microglial population is resistant to CSF1R inhibition in adult mouse brain von Zhan, Lihong, Fan, Li, Kodama, Lay, Sohn, Peter Dongmin, Wong, Man Ying, Mousa, Gergey Alzaem, Zhou, Yungui, Li, Yaqiao, Gan, Li

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Discovery of small molecules that normalize the transcriptome and enhance cysteine cathepsin activity in progranulin-deficient microglia von Telpoukhovskaia, Maria A., Liu, Kai, Sayed, Faten A., Etchegaray, Jon Iker, Xie, Min, Zhan, Lihong, Li, Yaqiao, Zhou, Yungui, Le, David, Bahr, Ben A., Bogyo, Matthew, Ding, Sheng, Gan, Li

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Mutation-dependent aggregation and toxicity in a Drosophila model for UBQLN2-associated ALS von Kim, Sang Hwa, Stiles, Shannon G, Feichtmeier, Joseph M, Ramesh, Nandini, Zhan, Lihong, Scalf, Mark A, Smith, Lloyd M, Pandey, Udai Bhan, Tibbetts, Randal S

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High-content RNAi screening identifies the Type 1 inositol triphosphate receptor as a modifier of TDP-43 localization and neurotoxicity von SANG HWA KIM, LIHONG ZHAN, HANSON, Keith A, TIBBETTS, Randal S

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Casein Kinase 1-dependent Phosphorylation of Familial Advanced Sleep Phase Syndrome-associated Residues Controls PERIOD 2 Stability von Shanware, Naval P., Hutchinson, John A., Kim, Sang Hwa, Zhan, Lihong, Bowler, Michael J., Tibbetts, Randal S.

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Identification of genetic modifiers of TDP-43 neurotoxicity in Drosophila von Zhan, Lihong, Hanson, Keith A, Kim, Sang Hwa, Tare, Apeksha, Tibbetts, Randal S

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Opposing roles of p38 and JNK in a Drosophila model of TDP-43 proteinopathy reveal oxidative stress and innate immunity as pathogenic components of neurodegeneration von Zhan, Lihong, Xie, Qijing, Tibbetts, Randal S

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Klotho controls the brain–immune system interface in the choroid plexus von Zhu, Lei, Stein, Liana R., Kim, Daniel, Ho, Kaitlyn, Yu, Gui-Qiu, Zhan, Lihong, Larsson, Tobias E., Mucke, Lennart

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A TREM2-activating antibody with a blood–brain barrier transport vehicle enhances microglial metabolism in Alzheimer’s disease models von van Lengerich, Bettina, Zhan, Lihong, Xia, Dan, Chan, Darren, Joy, David, Park, Joshua I., Tatarakis, David, Calvert, Meredith, Hummel, Selina, Lianoglou, Steve, Pizzo, Michelle E., Prorok, Rachel, Thomsen, Elliot, Bartos, Laura M., Beumers, Philipp, Capell, Anja, Davis, Sonnet S., de Weerd, Lis, Dugas, Jason C., Duque, Joseph, Earr, Timothy, Gadkar, Kapil, Giese, Tina, Gill, Audrey, Gnörich, Johannes, Ha, Connie, Kannuswamy, Malavika, Kim, Do Jin, Kunte, Sebastian T., Kunze, Lea H., Lac, Diana, Lechtenberg, Kendra, Leung, Amy Wing-Sze, Liang, Chun-Chi, Lopez, Isabel, McQuade, Paul, Modi, Anuja, Torres, Vanessa O., Nguyen, Hoang N., Pesämaa, Ida, Propson, Nicholas, Reich, Marvin, Robles-Colmenares, Yaneth, Schlepckow, Kai, Slemann, Luna, Solanoy, Hilda, Suh, Jung H., Thorne, Robert G., Vieira, Chandler, Wind-Mark, Karin, Xiong, Ken, Zuchero, Y. Joy Yu, Diaz, Dolo, Dennis, Mark S., Huang, Fen, Scearce-Levie, Kimberly, Watts, Ryan J., Haass, Christian, Lewcock, Joseph W., Di Paolo, Gilbert, Brendel, Matthias, Sanchez, Pascal E., Monroe, Kathryn M.

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Microglial NFκB-TNFα hyperactivation induces obsessive–compulsive behavior in mouse models of progranulin-deficient frontotemporal dementia von Krabbe, Grietje, Minami, S. Sakura, Etchegaray, Jon I., Taneja, Praveen, Djukic, Biljana, Davalos, Dimitrios, Le, David, Lo, Iris, Zhan, Lihong, Reichert, Meredith C., Sayed, Faten, Merlini, Mario, Ward, Michael E., Perry, David C., Lee, Suzee E., Sias, Ana, Parkhurst, Christopher N., Gan, Wen-biao, Akassoglou, Katerina, Miller, Bruce L., Farese, Robert V., Gan, Li

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Crystal structure of GnsA from Escherichia coli von Wei, Yong, Zhan, Lihong, Gao, Zengqiang, Privé, Gilbert G., Dong, Yuhui

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HMGA2 exhibits dRP/AP site cleavage activity and protects cancer cells from DNA-damage-induced cytotoxicity during chemotherapy von Summer, Heike, Li, Ou, Bao, Qiuye, Zhan, Lihong, Peter, Sabrina, Sathiyanathan, Padmapriya, Henderson, Dana, Klonisch, Thomas, Goodman, Steven D, Dröge, Peter

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A NOVEL ROLE FOR THE FTD-CAUSING PROTEIN PROGRANULIN IN APOPTOSIS SIGNALING von Clelland, Claire, Etchegaray, J. Iker, Kodama, Lay, Sayed, Faten, Sachdev, Aradhana, Li, Yaqiao, Le, David, Zhan, Lihong, Zhou, Yungui, Duong, Duc, Seyfried, Nicholas T., Kukar, Thomas G., Tan, Li Xuan, Lakkaraju, Aparna, Conklin, Bruce, Gan, Li

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P4‐511: A NOVEL ROLE FOR THE FTD‐CAUSING PROTEIN PROGRANULIN IN APOPTOSIS SIGNALING von Clelland, Claire, Etchegaray, J. Iker, Kodama, Lay, Sayed, Faten, Sachdev, Aradhana, Li, Yaqiao, Le, David, Zhan, Lihong, Zhou, Yungui, Duong, Duc, Seyfried, Nicholas T., Kukar, Thomas G., Tan, Li Xuan, Lakkaraju, Aparna, Conklin, Bruce, Gan, Li

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Conserved and distinct modes of CREB/ATF transcription factor regulation by PP2A/B56gamma and genotoxic stress von Shanware, Naval P, Zhan, Lihong, Hutchinson, John A, Kim, Sang Hwa, Williams, Leah M, Tibbetts, Randal S

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